公开(公告)号：ITFI920146A1

公开(公告)日：1994-01-18

申请号：ITFI920146

申请日：1992-07-17

Applicant: SCLAVO SPA

Inventor： PRESENTINI RIVO ,  TERRANA BENEDETTO

IPC: C08G20060101 ,  C12N9/08 ,  G01N33/531 ,  G01N33/535 ,  G01N33/543

公开(公告)号：IT1226551B

公开(公告)日：1991-01-24

申请号：IT2155388

申请日：1988-07-29

Applicant: SCLAVO SPA

Inventor： TECCE MARIO FELICE ,  GIULIANI MARZIA MONICA ,  RICCI STEFANO ,  RATTI GIULIO ,  TERRANA BENEDETTO

IPC: G01N33/574 ,  C07K14/00 ,  C07K14/47 ,  C07K16/00 ,  C07K16/30 ,  C07K19/00 ,  C12N1/21 ,  C12N9/12 ,  C12N15/12 ,  C12P21/02 ,  C12P21/08 ,  C12R1/19 ,  G01N33/577 ,  A61K

Abstract: A synthetic peptide endowed with immunological activity is disclosed, which is capable of inducing in mammals the formation of anti-peptide antibodies capable of recognizing human alpha-fetoprotein and of reacting with it, and incapable of recognizing albumin or its degradation products, with said peptide being essentially constituted by the aminoacidic sequence of formula (I), corresponding to 38- 119 region of human alpha-fetoprotein. Furthermore, the methods and means for preparing said peptide by means of the recombinant DNA techniques are reported. The synthetic peptide (I), like the polyclonal and monoclonal antipeptide antibodies are particularly suitable for the early diagnosis of hepatocellular carcinoma and of teratocarcinoma.

公开(公告)号：IT8821553D0

公开(公告)日：1988-07-29

申请号：IT2155388

申请日：1988-07-29

Applicant: SCLAVO SPA

Inventor： TECCE MARIO FELICE ,  GIULIANI MARZIA MONICA ,  RICCI STEFANO ,  RATTI GIULIO ,  TERRANA BENEDETTO

IPC: G01N33/574 ,  C07K14/00 ,  C07K14/47 ,  C07K16/00 ,  C07K16/30 ,  C07K19/00 ,  C12N1/21 ,  C12N9/12 ,  C12N15/12 ,  C12P21/02 ,  C12P21/08 ,  C12R1/19 ,  G01N33/577 ,  A61K

Abstract: A synthetic peptide endowed with immunological activity is disclosed, which is capable of inducing in mammals the formation of anti-peptide antibodies capable of recognizing human alpha-fetoprotein and of reacting with it, and incapable of recognizing albumin or its degradation products, with said peptide being essentially constituted by the aminoacidic sequence of formula (I), corresponding to 38- 119 region of human alpha-fetoprotein. Furthermore, the methods and means for preparing said peptide by means of the recombinant DNA techniques are reported. The synthetic peptide (I), like the polyclonal and monoclonal antipeptide antibodies are particularly suitable for the early diagnosis of hepatocellular carcinoma and of teratocarcinoma.

公开(公告)号：ITFI920146D0

公开(公告)日：1992-07-17

申请号：ITFI920146

申请日：1992-07-17

Applicant: SCLAVO SPA

Inventor： PRESENTINI RIVO ,  TERRANA BENEDETTO

IPC: C12N9/08 ,  G01N33/531 ,  G01N33/535 ,  G01N33/543

公开(公告)号：IT1202573B

公开(公告)日：1989-02-09

申请号：IT1943387

申请日：1987-02-20

Applicant: SCLAVO SPA

Inventor： TECCE MARIO FELICE ,  TERRANA BENEDETTO

IPC: C12P20060101 ,  C12P

Abstract: It is feasible with the aid of an indicator-cartridge to determine even trace quantities of carbon monoxide in air and in various gas mixts.. Determination is based on easily discernible colour reactions on the charge of the cartridge. The charge contains chlorine and chloride

公开(公告)号：IT8719433D0

公开(公告)日：1987-02-20

申请号：IT1943387

申请日：1987-02-20

Applicant: SCLAVO SPA

Inventor： TECCE MARIO FELICE ,  TERRANA BENEDETTO

IPC: C12P20060101 ,  C12P