公开(公告)号：DE69905524T2

公开(公告)日：2003-12-11

申请号：DE69905524

申请日：1999-07-26

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN ,  CAIGNARD DANIEL-HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：DE69905524D1

公开(公告)日：2003-04-03

申请号：DE69905524

申请日：1999-07-26

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN ,  CAIGNARD DANIEL-HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：HK1024244A1

公开(公告)日：2000-10-05

申请号：HK00103590

申请日：2000-06-15

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIIN ,  CAIGNARD DANIEL-HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14 ,  C07D ,  A61K ,  A61P

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：ES2192827T3

公开(公告)日：2003-10-16

申请号：ES99401892

申请日：1999-07-26

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：AU752505B2

公开(公告)日：2002-09-19

申请号：AU4117199

申请日：1999-07-27

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CELCILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN ,  CAIGNARD DANIEL HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14 ,  C07D513/04

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：HU226377B1

公开(公告)日：2008-10-28

申请号：HU9902546

申请日：1999-07-27

Applicant: SERVIER LAB

Inventor： ATASSI GHANEM ,  CAIGNARD DANIEL-HENRI ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  PIERRE ALAIN ,  RAULT SYLVAIN ,  RENARD PIERRE ,  ROBBA MAX

IPC: A61K31/00 ,  C07D495/14 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：DK0982308T3

公开(公告)日：2003-05-12

申请号：DK99401892

申请日：1999-07-26

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN ,  CAIGNARD DANIEL-HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：AT233266T

公开(公告)日：2003-03-15

申请号：AT99401892

申请日：1999-07-26

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN ,  CAIGNARD DANIEL-HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14 ,  C07D333/00 ,  C07D209/00

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：NO313521B1

公开(公告)日：2002-10-14

申请号：NO993608

申请日：1999-07-23

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  ENGUEHARD CECILE ,  LANCELOT JEAN-CHARLES ,  ROBBA MAX ,  ATASSI GHANEM ,  PIERRE ALAIN ,  CAIGNARD DANIEL-HENRI ,  RENARD PIERRE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.

公开(公告)号：AU4117199A

公开(公告)日：2000-02-17

申请号：AU4117199

申请日：1999-07-27

Applicant: SERVIER LAB

Inventor： RAULT SYLVAIN ,  RENARD PIERRE ,  CAIGNARD DANIEL HENRI ,  PIERRE ALAIN ,  ATASSI GHANEM ,  ROBBA MAX ,  LANCELOT JEAN-CHARLES ,  ENGUEHARD CECILE

IPC: A61K31/00 ,  A61K31/40 ,  A61K31/407 ,  A61P35/00 ,  C07D495/14 ,  C07D513/04

Abstract: A compound selected from those of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, R2 represents optionally substituted aryl or heteroaryl, R3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino, their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.