ESTIMATING APPARATUS AND ESTIMATING METHOD

    公开(公告)号:SG183946A1

    公开(公告)日:2012-10-30

    申请号:SG2012066239

    申请日:2011-03-07

    Abstract: ESTIMATING APPARATUS AND ESTIMATING METHOD Abstract[Abstract][Object] To provide an estimating apparatus and anestimating method capable of estimating process of therapy using a laser the catheter 300 accurately in real time.[Solving Means]A photodynamic therapy apparatus 1 as an estimating apparatus is an apparatus for irradiating atissue having absorbed photo-sensitive pharmaceutical,the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser the catheter 300, including a connector 210, a lightsource 110, and a light detection unit 130. The laser the catheter 300 is capable of being attached/detached to/from the connector 210. The light source 110 outputs the excitation light to the laser the catheter 300 via the connector 210. The light detection unit 130 detectsintensity or a spectrum of the fluorescence, the fluorescence being entered from the laser the catheter 300 via the connector 210, to estimate whether the tissue has changed because of reaction between the excitation light emitted from the tip portion of thelaser the catheter 300 and the photo-sensitive pharmaceutical absorbed in the tissue.Fig. 3

    CALCULATION APPARATUS AND CALCULATION METHOD

    公开(公告)号:SG183935A1

    公开(公告)日:2012-10-30

    申请号:SG2012065967

    申请日:2011-03-07

    Abstract: CALCULATION APPARATUS AND CALCULATION METHODAbstract[Abstract][Object] To provide a calculation apparatus and acalculation method capable of calculatingpharmaceutical concentration in a tissue in real time. [Solving Means] A photodynamic therapy apparatus 1 as a calculation apparatus is an apparatus forirradiating a tissue having absorbed photo-sensitivepharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, with the excitation light emitted from a tip portion ofa laser catheter 300, including a connector 210, alight source 110, and a light detection unit 130. The laser catheter 300 is capable of beingattached/detached to/from the connector 210. The light source 110 outputs the excitation light to the laser catheter 300 via the connector 210. The light detectionunit 130 detects intensity of the fluorescence, the fluorescence being entered from the laser catheter 300 via the connector 210, to calculate concentration of the photo-sensitive pharmaceutical in a tissue, the tipportion of the laser catheter 300 contacting the tissue.Fig. 3

    EVALUATION DEVICE AND EVALUATION METHOD
    8.
    发明公开
    EVALUATION DEVICE AND EVALUATION METHOD 有权
    评估设备和评估程序

    公开(公告)号:EP2548616A4

    公开(公告)日:2013-08-28

    申请号:EP11755846

    申请日:2011-03-07

    Abstract: [Object] To provide an estimating apparatus and an estimating method capable of estimating process of therapy using a laser the catheter 300 accurately in real time. [Solving Means] A photodynamic therapy apparatus 1 as an estimating apparatus is an apparatus for irradiating a tissue having absorbed photo-sensitive pharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser the catheter 300, including a connector 210, a light source 110, and a light detection unit 130. The laser the catheter 300 is capable of being attached/detached to/from the connector 210. The light source 110 outputs the excitation light to the laser the catheter 300 via the connector 210. The light detection unit 130 detects intensity or a spectrum of the fluorescence, the fluorescence being entered from the laser the catheter 300 via the connector 210, to estimate whether the tissue has changed because of reaction between the excitation light emitted from the tip portion of the laser the catheter 300 and the photo-sensitive pharmaceutical absorbed in the tissue.

    9.
    发明专利
    未知

    公开(公告)号:DE60331042D1

    公开(公告)日:2010-03-11

    申请号:DE60331042

    申请日:2003-10-23

    Abstract: Nitride semiconductor wafers which are produced by epitaxially grown nitride films on a foreign undersubstrate in vapor phase have strong inner stress due to misfit between the nitride and the undersubstrate material. A GaN wafer which has made by piling GaN films upon a GaAs undersubstrate in vapor phase and eliminating the GaAs undersubstrate bends upward due to the inner stress owing to the misfit of lattice constants between GaN and GaAs. Ordinary one-surface polishing having the steps of gluing a wafer with a surface on a flat disc, bringing another surface in contact with a lower turntable, pressing the disc, rotating the disc, revolving the turntable and whetting the lower surface, cannot remedy the inherent distortion. The Distortion worsens morphology of epitaxial wafers, lowers yield of via-mask exposure and invites cracks on surfaces. Nitride crystals are rigid but fragile. Chemical/mechanical polishing has been requested in vain. Current GaN wafers have roughened bottom surfaces, which induce contamination of particles and fluctuation of thickness. Circular nitride wafers having a diameter larger than 45mm are made and polished. Gross-polishing polishes the nitride wafers in a pressureless state with pressure less than 60g/cm by lifting up the upper turntable for remedying distortion. Distortion height H at a center is reduced to H≤12 mu m. Minute-polishing is a newly-contrived CMP which polishes the nitride wafers with a liquid including potassium hydroxide, potassium peroxodisulfate and powder, irradiates the potassium peroxodisulfate with ultraviolet rays. The CMP-polished top surface has roughness RMS of 0.1nm≤RMS≤5nm or more favorably 0.1nm≤RMS≤0.5nm. The CMP-polished bottom surface has roughness RMS of 0.1nm≤RMS≤5000nm or more favorably 0.1nm≤RMS≤2nm. TTV is less than 10 mu m.

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