-
公开(公告)号：EP0886637A1
公开(公告)日：1998-12-30
申请号：EP96903604
申请日：1996-02-01
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU JOHN R II , SHARP DARU YOUNG , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN A , LAWRENCE R MICHAEL , MAGNIN DAVID R , POSS MICHAEL A , ROBL JEFFREY A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A
IPC: A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/4468 , A61K31/47 , A61K31/495 , A61K31/505 , A61K31/52 , A61K31/535 , A61P3/06 , A61P9/10 , A61P43/00 , C07D211/00 , C07D211/56 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/98 , C07D215/38 , C07D217/00 , C07D217/22 , C07D221/16 , C07D241/04 , C07D401/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , C07D401/06 , C07D405/04 , C07D409/04
CPC classification number: C07D401/04 , C07D211/58 , C07D211/60 , C07D211/94 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , G01N2800/044
Abstract: Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure (a, b, c or d) wherein R1 to R6, Q, and X are as defined herein.
-
2.发明专利
公开(公告)号：SK113597A3
公开(公告)日：1998-09-09
申请号：SK113597
申请日：1996-02-01
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU II JOHN R , SHARP DARU YOUNG , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN K , LAWRENCE MICHAEL R , MAGNIN DAVID R , POSS MICHAEL A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A , ROBL JEFFREY A
IPC: A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/4468 , A61K31/47 , A61K31/495 , A61K31/505 , A61K31/52 , A61K31/535 , A61P3/06 , A61P9/10 , A61P43/00 , C07D211/00 , C07D211/56 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/98 , C07D215/38 , C07D217/00 , C07D217/22 , C07D221/16 , C07D241/04 , C07D401/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , C07D401/06 , C07D405/04 , C07D409/04
Abstract: Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure defined herein.
-
公开(公告)号：LT4367B
公开(公告)日：1998-08-25
申请号：LT97152
申请日：1997-09-19
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU-II JOHN R , SHARP DARU YOUNG , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN K , LAWRENCE R MICHAEL , MAGNIN DAVID R , POSS MICHAEL A , ROBL JEFFREY A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A
IPC: A61K20060101 , A61K31/445 , C07D20060101 , C07D211/58 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12
Abstract: Invention describes compounds that inhibit an albumen carrying microsome triglyceride and therefore they are suitable for reduction of lipid amount in a serum and for treatment of atherosclerosis and diseases related to the same. There are following structural formulas of compounds: where R -R , Q and X have meanings given in description of the invention.
-
公开(公告)号：BG101717A
公开(公告)日：1998-02-27
申请号：BG10171797
申请日：1997-07-01
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU II JOHN R , SHARP DARU Y , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN K , LAWRENCE MICHAEL R , MAGNIN DAVID R , POSS MICHAEL A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A , ROBL JEFFREY A
IPC: A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/4468 , A61K31/47 , A61K31/495 , A61K31/505 , A61K31/52 , A61K31/535 , A61P3/06 , A61P9/10 , A61P43/00 , C07D211/00 , C07D211/56 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/98 , C07D215/38 , C07D217/00 , C07D217/22 , C07D221/16 , C07D241/04 , C07D401/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12
Abstract: Compounds are provided which inhibit microsomal triglyceridetransfer protein and thus are useful for lowering serum lipids andtreating atherosclerosis and related diseases. The compounds areof formulasorwherein R1 to R6, Q, and X are as defined in the description
-
公开(公告)号：CZ261797A3
公开(公告)日：1998-01-14
申请号：CZ261797
申请日：1996-02-01
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU II JOHN R , SHARP DARU YOUNG , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN K , LAWRENCE R MICHAEL , MAGNIN DAVID R , POSS MICHAEL A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A , ROBL JEFFREY A
IPC: A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/4468 , A61K31/47 , A61K31/495 , A61K31/505 , A61K31/52 , A61K31/535 , A61P3/06 , A61P9/10 , A61P43/00 , C07D211/00 , C07D211/56 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/98 , C07D215/38 , C07D217/00 , C07D217/22 , C07D221/16 , C07D241/04 , C07D401/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , C07D401/06 , C07D405/04
Abstract: Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure defined herein.
-
Patent Agency Ranking
公开(公告)号：ZA961340B
公开(公告)日：1997-09-11
申请号：ZA961340
申请日：1996-02-20
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU JOHN R II , GREGG RICHARD E , DICKSON JOHN K , MAGNIN DAVID R , SULSKY RICHARD B , LAWSON JOHN E , PARTYKA RICHARD A , SHARP DARU YOUNG , BILLER SCOTT A , LAWRENCE R MICHAEL , POSS MICHAEL A , TINO JOSEPH A , HOLAVA HENRY M , ROBL JEFFREY A
IPC: A61K20060101 , A61K31/445 , C07D20060101 , C07D211/58 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D , A61K
-
公开(公告)号：ZA9601340B
公开(公告)日：1997-09-11
申请号：ZA9601340
申请日：1996-02-20
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU JOHN R II , GREGG RICHARD E , DICKSON JOHN K , MAGNIN DAVID R , SULSKY RICHARD B , LAWSON JOHN E , PARTYKA RICHARD A , SHARP DARU YOUNG , BILLER SCOTT A , LAWRENCE R MICHAEL , POSS MICHAEL A , TINO JOSEPH A , HOLAVA HENRY M , ROBL JEFFREY A
IPC: A61K20060101 , A61K31/445 , C07D20060101 , C07D211/58 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D , A61K
-
公开(公告)号：FI973416A0
公开(公告)日：1997-08-20
申请号：FI973416
申请日：1997-08-20
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU II JOHN R , SHARP DARU YOUNG , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN A , LAWRENCE R MICHAEL , MAGNIN DAVID R , POSS MICHAEL A , ROBL JEFFREY A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A
IPC: A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/4468 , A61K31/47 , A61K31/495 , A61K31/505 , A61K31/52 , A61K31/535 , A61P3/06 , A61P9/10 , A61P43/00 , C07D211/00 , C07D211/56 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/98 , C07D215/38 , C07D217/00 , C07D217/22 , C07D221/16 , C07D241/04 , C07D401/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D419/12 , C07D
Abstract: Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure defined herein.
-
公开(公告)号：HK17590A
公开(公告)日：1990-03-16
申请号：HK17590
申请日：1990-03-08
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： LAWSON JOHN E , MATIER WILLIAM L , ROTH HERBERT R
IPC: A61K31/496 , A61K31/505 , A61P9/12 , C07D209/14 , C07D235/12 , C07D235/14 , C07D239/34 , C07D239/46 , C07D239/47 , C07D239/48 , C07D333/20 , C07D333/58 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D239/32 , C07D239/28
Abstract: 1-(4-Pyrimidinyloxy)-3-(hetarylalkylamino)-2-propanols are cardiovascular agents having a range of vasodilator and adrenergic beta-receptor blocking activities making these compounds useful anti-hypertensive agents. Preferred compounds bear a hydrazino or hydrazono substituent in the 2- position of the pyrimidine ring.
-
公开(公告)号：LT97152A
公开(公告)日：1998-04-27
申请号：LT97152
申请日：1997-09-19
Applicant: SQUIBB BRISTOL MYERS CO
Inventor： WETTERAU-II JOHN R , SHARP DARU YOUNG , GREGG RICHARD E , BILLER SCOTT A , DICKSON JOHN K , LAWRENCE R MICHAEL , MAGNIN DAVID R , POSS MICHAEL A , ROBL JEFFREY A , SULSKY RICHARD B , TINO JOSEPH A , LAWSON JOHN E , HOLAVA HENRY M , PARTYKA RICHARD A
IPC: A61K20060101 , A61K31/445 , C07D20060101 , C07D211/58 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12
-
-
-
-
-
-
-
-
-
Search Results
33
records
(took 0.026 seconds)
