公开(公告)号：AU2010200648A1

公开(公告)日：2010-03-11

申请号：AU2010200648

申请日：2010-02-22

Applicant: STICHTING TECH WETENSCHAPP

Inventor： DRIJFHOUT JAN WOUTER ,  PRUIJIN GERARDUS JOZEF MARIA ,  BOEKEL MARTINUS ADRIANUS MARIA VAN ,  VENROOIJ WALTHERUS JACOBUS WILHELMUS VAN

IPC: G01N33/564 ,  C07K7/06 ,  C07K7/08 ,  C07K7/54 ,  C07K7/64 ,  C07K14/47 ,  G01N33/53

Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.