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1.发明申请METHOD OF DETECTING AUTOANTIBODIES FROM PATIENTS SUFFERING FROM RHEUMATOID ARTHRITIS, A PEPTIDE AND AN ASSAYKIT 审中-公开从患有炎热性疾病的患者中检测自身抗体的方法，肽和测定试剂
公开(公告)号：WO03050542A2
公开(公告)日：2003-06-19
申请号：PCT/NL0200815
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP , VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
CPC classification number: G01N33/564 , C07K7/08 , C07K7/52 , C07K7/64 , C07K14/4713 , G01N2410/00 , G01N2800/102 , Y10S435/973 , Y10S435/975 , Y10S530/806
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
Abstract translation: 本发明涉及从患有类风湿性关节炎的患者中检测自身抗体的方法。 为此，根据本发明，使用至少两个肽单元，其中至少一个肽单元包含不衍生自（pro）填充蛋白，纤维蛋白，纤维蛋白原，波形蛋白，细胞角蛋白1和细胞角蛋白9的部分，哪个肽单元 包含基序XG和包含基序XnonG的肽单元，其中X是瓜氨酸或其类似物，而nonG是除甘氨酸以外的氨基酸。
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公开(公告)号：DK1456662T3
公开(公告)日：2006-09-18
申请号：DK02786237
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：BR0214872A
公开(公告)日：2004-10-26
申请号：BRPI0214872
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：AU2002354397A1
公开(公告)日：2003-06-23
申请号：AU2002354397
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： PRUIJN GERARDUS JOZEF MARIA , VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：CA2708463A1
公开(公告)日：2003-06-19
申请号：CA2708463
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
IPC: C07K7/08 , C07K7/06 , C07K7/54 , C07K7/64 , C07K14/47 , C40B30/04 , G01N33/53 , G01N33/564 , G01N33/68
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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Patent Agency Ranking
公开(公告)号：HK1128329A1
公开(公告)日：2009-10-23
申请号：HK09105983
申请日：2009-07-03
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WILHELMUS VAN , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA VAN , PRUIJN GERARDUS JOZEF MARIA
IPC: G01N20060101 , C07K20060101 , C07K7/06 , C07K7/08 , C07K7/54 , C07K14/47 , G01N33/53 , G01N33/564
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：AU2010200648A1
公开(公告)日：2010-03-11
申请号：AU2010200648
申请日：2010-02-22
Applicant: STICHTING TECH WETENSCHAPP
Inventor： DRIJFHOUT JAN WOUTER , PRUIJIN GERARDUS JOZEF MARIA , BOEKEL MARTINUS ADRIANUS MARIA VAN , VENROOIJ WALTHERUS JACOBUS WILHELMUS VAN
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：HK1072805A1
公开(公告)日：2005-09-09
申请号：HK05102287
申请日：2005-03-15
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
IPC: G01N20060101 , C07K20060101 , C07K7/06 , C07K7/08 , C07K7/54 , C07K14/47 , G01N33/53 , G01N33/564
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：CA2489167A1
公开(公告)日：2003-06-19
申请号：CA2489167
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： PRUIJN GERARDUS JOZEF MARIA , VAN VENROOIJ WALTHERUS JACOBUS , VAN BOEKEL MARTINUS ADRIANUS M , DRIJFHOUT JAN WOUTER
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention , at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glyci ne.
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公开(公告)号：CA2793087A1
公开(公告)日：2011-09-22
申请号：CA2793087
申请日：2011-03-15
Applicant: ACADEMISCH ZIEKENHUIS LEIDEN , STICHTING TECH WETENSCHAPP
IPC: A61K39/395 , C07K14/33 , C07K16/12
Abstract: The present invention relates to conjugates comprising a peptide of at least 10 amino acid residues comprising the amino acid sequence GITELKKL for induction of potent humoral and cellular immune responses when administered to subjects having antibodies against tetanus toxoid. In one embodiment the invention relates to a prophylactic and therapeutic vaccine and in a further embodiment the invention relates to the treatment or prevention of cancer or an infectious disease.
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