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1.发明申请PEPTIDE DERIVED FROM AN ANTIGEN RECOGNIZED BY AUTOANTIBODIES FROM PATIENTS WITH RHEUMATOID ARTHRITIS, ANTIBODY DIRECTED AGAINST SAID PEPTIDE, A COMBINATORIAL ANTIGEN, AND A METHOD OF DETECTING AUTO-IMMUNE ANTIBODIES 审中-公开由抗自身抗体鉴定的抗生素衍生自患有炎症性角膜炎的患者的抗原，针对抗原肽的抗体，组合抗原以及检测自身免疫抗体的方法
公开(公告)号：WO9822503A3
公开(公告)日：1998-08-27
申请号：PCT/NL9700624
申请日：1997-11-14
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP , VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
IPC: C07K7/08 , C07K14/47 , C07K16/18 , C12P21/08 , G01N33/564
CPC classification number: G01N33/6893 , C07K14/47 , C07K14/4713 , C07K16/18 , G01N33/564 , G01N2333/46 , G01N2800/10 , G01N2800/102 , G01N2800/24
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：DK0941244T3
公开(公告)日：2007-04-30
申请号：DK97912577
申请日：1997-11-14
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , SCHELLEKENS GERARDUS ANTONIUS , HOET RENE MICHAEL ANTONIUS , RAATS JOZEF MARIA HENDRIK
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：AT352560T
公开(公告)日：2007-02-15
申请号：AT97912577
申请日：1997-11-14
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：AU4970797A
公开(公告)日：1998-06-10
申请号：AU4970797
申请日：1997-11-14
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
IPC: C07K7/08 , C07K14/47 , C07K16/18 , C12P21/08 , G01N33/564
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：NL1004539C2
公开(公告)日：1998-05-20
申请号：NL1004539
申请日：1996-11-15
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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Patent Agency Ranking
公开(公告)号：CA2272573C
公开(公告)日：2010-02-02
申请号：CA2272573
申请日：1997-11-14
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：ES2281095T3
公开(公告)日：2007-09-16
申请号：ES97912577
申请日：1997-11-14
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
Abstract: LA PRESENTE INVENCION SE REFIERE A UN PEPTIDO DERIVADO DE UN ANTIGENO RECONOCIDO POR AUTOANTICUERPOS; DICHO PEPTIDO REACCIONA CON ANTICUERPOS AUTOINMUNES QUE PROCEDEN DE UN PACIENTE QUE PADECE DE POLIARTRITIS REUMATOIDE. EL PEPTIDO DE ESTA INVENCION TIENE UN RESTO ARGININO MODIFICADO. ESTA INVENCION SE REFIERE TAMBIEN A UNOS ANTICUERPOS DIRIGIDOS CONTRA ESTE PEPTIDO, ASI COMO A UN PROCEDIMIENTO DE DETECCION DE ANTICUERPOS AUTOINMUNES.
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公开(公告)号：PT941244E
公开(公告)日：2007-02-28
申请号：PT97912577
申请日：1997-11-14
Applicant: STICHTING TECH WETENSCHAPP
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公开(公告)号：AU741850B2
公开(公告)日：2001-12-13
申请号：AU4970797
申请日：1997-11-14
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
IPC: C07K7/08 , C07K14/47 , C07K16/18 , C12P21/08 , G01N33/564
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：CA2272573A1
公开(公告)日：1998-05-28
申请号：CA2272573
申请日：1997-11-14
Applicant: STICHTING TECH WETENSCHAPP , STICHTING SCHEIKUNDIG ONDERZOE
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , HOET RENE MICHAEL ANTONIUS , RAATS JOZEF MARIA HENDRIK , SCHELLEKENS GERARDUS ANTONIUS
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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