-
公开(公告)号：WO0032629A3
公开(公告)日：2000-08-17
申请号：PCT/NL9900732
申请日：1999-12-01
Applicant: STICHTING TECH WETENSCHAPP , NIEUW AMERONGEN ARIE VAN , VEERMAN ENGELMUNDUS CORNELIS I , T HOF WILLEM VAN , NIBBERING PETER HENDRICUS
Inventor： VAN NIEUW AMERONGEN ARIE , VEERMAN ENGELMUNDUS CORNELIS I , VAN T HOF WILLEM , NIBBERING PETER HENDRICUS
CPC classification number: C07K7/08 , A61K38/00 , C07K14/4723
Abstract: The invention relates to peptides for use as antiviral agent, consisting of an amino acid chain which contains a domain of 10 to 25 amino acids, wherein the majority of the amino acids of the one half of the domain are positively charged amino acids and the majority of the amino acids of the other half of the domain are uncharged amino acids. The invention further relates to oligomers of these peptides consisting of at least two such peptides which are coupled to each other, optionally via a spacer, for use as antiviral agent, in addition to the use of the peptides and/or oligomers for the manufacture of a medicine for treating viral infections.
Abstract translation: 本发明涉及用作抗病毒剂的肽，其由包含10至25个氨基酸的结构域的氨基酸链组成，其中该域的一半的大部分氨基酸是带正电荷的氨基酸，并且多数 的另一半结构域的氨基酸是不带电荷的氨基酸。 本发明还涉及由至少两种这样的肽组成的这些肽的寡聚体，除了使用肽和/或低聚物以外，还可以任选经由间隔物彼此偶联，用作抗病毒剂。 用于治疗病毒感染的药物。
-
公开(公告)号：WO9937678A3
公开(公告)日：1999-10-14
申请号：PCT/NL9900045
申请日：1999-01-26
Applicant: STICHTING TECH WETENSCHAPP , NIEUW AMERONGEN ARIE VAN , VEERMAN ENGELMUNDUS CORNELIS I , T HOF WILLEM VAN , HELMERHORST EVA JOSEPHINE
Inventor： VAN NIEUW AMERONGEN ARIE , VEERMAN ENGELMUNDUS CORNELIS I , VAN T HOF WILLEM , HELMERHORST EVA JOSEPHINE
IPC: A61K9/06 , A61K9/12 , A61K38/00 , A61P31/04 , A61P31/10 , C07K7/08 , C07K14/47 , A61K38/10 , A61K38/17
CPC classification number: C07K7/08 , A61K38/00 , C07K14/4723
Abstract: The invention relates to peptides with antimicrobial activity, consisting of an amino acid chain which contains a domain of 10 to 25 amino acids, wherein the majority of the amino acids of the one half of the domain are positively charged amino acids and the majority of the amino acids of the other half of the domain are uncharged amino acids.
Abstract translation: 本发明涉及具有抗微生物活性的肽，其由含有10至25个氨基酸的结构域的氨基酸链组成，其中结构域的一半的大部分氨基酸为带正电荷的氨基酸，并且大部分 另一半结构域的氨基酸是不带电荷的氨基酸。
-
公开(公告)号：CA2319094A1
公开(公告)日：1999-07-29
申请号：CA2319094
申请日：1999-01-26
Applicant: STICHTING TECH WETENSCHAPP
Inventor： HELMERHORST EVA JOSEPHINE , VAN T HOF WILLEM , VEERMAN ENGELMUNDUS CORNELIS I , VAN NIEUW AMERONGEN ARIE
IPC: A61K9/06 , A61K9/12 , A61K38/00 , A61P31/04 , A61P31/10 , C07K7/08 , C07K14/47 , A61K38/10 , A61K38/17
Abstract: The invention relates to peptides with antimicrobial activity, consisting of an amino acid chain which contains a domain of 10 to 25 amino acids, wherein the majority of the amino acids of the one half of the domain are positively charged amino acids and the majority of the amino acids of the other half of the domain are uncharged amino acids.
-
公开(公告)号：AU1545495A
公开(公告)日：1995-08-21
申请号：AU1545495
申请日：1995-02-02
Applicant: STICHTING TECH WETENSCHAPP
Inventor： AMERONGEN ARIE VAN NIEUW , VEERMAN ENGELMUNDUS CORNELIS I , REIJDEN WILLY ALEXANDER VAN DE
IPC: A61K8/00 , A61K8/20 , A61K8/21 , A61K8/24 , A61K8/33 , A61K8/40 , A61K8/64 , A61K8/73 , A61K31/06 , A61K31/14 , A61K31/16 , A61K31/19 , A61K31/20 , A61K31/42 , A61K31/425 , A61K31/715 , A61K31/765 , A61K31/78 , A61K33/14 , A61K33/16 , A61K33/24 , A61K33/42 , A61K38/17 , A61K45/06 , A61P1/02 , A61P27/02 , A61Q11/00
Abstract: PCT No. PCT/NL95/00046 Sec. 371 Date Sep. 23, 1996 Sec. 102(e) Date Sep. 23, 1996 PCT Filed Feb. 2, 1995 PCT Pub. No. WO95/20971 PCT Pub. Date Aug. 10, 1995The present invention relates to a therapeutic composition comprising an aqueous solution of at least one polymer and at least one electrolyte, wherein the aqueous solution is preferably buffered and optionally contains at least one mucin. The polymer can be chosen for instance from the group which consists of scleroglucan, guar gum, xanthane gum, sodium carboxymethyl cellulose, hydroxyethyl cellulose, polyacrylic acid and polyvinyl alcohol. The therapeutic composition according to the invention can serve as saliva substitution agent, artificial tear water, in a mouth rinse or in a toothpaste.
-
Patent Agency Ranking
公开(公告)号：AU1695900A
公开(公告)日：2000-06-19
申请号：AU1695900
申请日：1999-12-01
Applicant: STICHTING TECH WETENSCHAPP
Inventor： AMERONGEN ARIE VAN NIEUW , VEERMAN ENGELMUNDUS CORNELIS I , WILLEM T HOF VAN , NIBBERING PETER HENDRICUS
Abstract: The invention relates to peptides for use as antiviral agent, consisting of an amino acid chain which contains a domain of 10 to 25 amino acids, wherein the majority of the amino acids of the one half of the domain are positively charged amino acids and the majority of the amino acids of the other half of the domain are uncharged amino acids. The invention further relates to oligomers of these peptides consisting of at least two such peptides which are coupled to each other, optionally via a spacer, for use as antiviral agent, in addition to the use of the peptides and/or oligomers for the manufacture of a medicine for treating viral infections.
-
公开(公告)号：NL1008139C2
公开(公告)日：1999-07-28
申请号：NL1008139
申请日：1998-01-27
Applicant: STICHTING TECH WETENSCHAPP
-
公开(公告)号：NL1010692C2
公开(公告)日：2000-06-06
申请号：NL1010692
申请日：1998-12-01
Applicant: STICHTING TECH WETENSCHAPP
Inventor： AMERONGEN ARIE VAN NIEUW , VEERMAN ENGELMUNDUS CORNELIS I , HOF WILLEM VAN T , NIBBERING PETER HENDRICUS
Abstract: The invention relates to peptides for use as antiviral agent, consisting of an amino acid chain which contains a domain of 10 to 25 amino acids, wherein the majority of the amino acids of the one half of the domain are positively charged amino acids and the majority of the amino acids of the other half of the domain are uncharged amino acids. The invention further relates to oligomers of these peptides consisting of at least two such peptides which are coupled to each other, optionally via a spacer, for use as antiviral agent, in addition to the use of the peptides and/or oligomers for the manufacture of a medicine for treating viral infections.
-
8.发明专利
公开(公告)号：NL1008745C2
公开(公告)日：1999-10-01
申请号：NL1008745
申请日：1998-03-30
Applicant: STICHTING TECH WETENSCHAPP
Inventor： AMERONGEN ARIE VAN NIEUW , VEERMAN ENGELMUNDUS CORNELIS I , HOF WILLEM VAN T , REIJDEN WILLY ALEXANDER VAN DE , RUISSEN ANNETJE LENA ADRIANA
Abstract: Conjugates of an antifungal peptide and a mucoadhesive polymer are new. The peptide has a domain of 10 - 25 amino acids in which most of the amino acids in one half of the domain are positively charged amino acids and most of the amino acids in the other half of the domain are uncharged amino acids.
-
公开(公告)号：NL9400160A
公开(公告)日：1995-09-01
申请号：NL9400160
申请日：1994-02-02
Applicant: STICHTING TECH WETENSCHAPP
Inventor： AMERONGEN ARIE VAN NIEUW , VEERMAN ENGELMUNDUS CORNELIS I , REIJDEN WILLY ALEXANDER VAN DE
IPC: A61K8/00 , A61K8/20 , A61K8/21 , A61K8/24 , A61K8/33 , A61K8/40 , A61K8/64 , A61K8/73 , A61K31/06 , A61K31/14 , A61K31/16 , A61K31/19 , A61K31/20 , A61K31/42 , A61K31/425 , A61K31/715 , A61K31/765 , A61K31/78 , A61K33/14 , A61K33/16 , A61K33/24 , A61K33/42 , A61K38/17 , A61K45/06 , A61P1/02 , A61P27/02 , A61Q11/00 , A61K31/70 , A61K7/16
Abstract: PCT No. PCT/NL95/00046 Sec. 371 Date Sep. 23, 1996 Sec. 102(e) Date Sep. 23, 1996 PCT Filed Feb. 2, 1995 PCT Pub. No. WO95/20971 PCT Pub. Date Aug. 10, 1995The present invention relates to a therapeutic composition comprising an aqueous solution of at least one polymer and at least one electrolyte, wherein the aqueous solution is preferably buffered and optionally contains at least one mucin. The polymer can be chosen for instance from the group which consists of scleroglucan, guar gum, xanthane gum, sodium carboxymethyl cellulose, hydroxyethyl cellulose, polyacrylic acid and polyvinyl alcohol. The therapeutic composition according to the invention can serve as saliva substitution agent, artificial tear water, in a mouth rinse or in a toothpaste.
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.023 seconds)
