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公开(公告)号：NL1019540C2
公开(公告)日：2003-07-01
申请号：NL1019540
申请日：2001-12-11
Applicant: STICHTING TECH WETENSCHAPP
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公开(公告)号：BR0214872A
公开(公告)日：2004-10-26
申请号：BRPI0214872
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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Patent Agency Ranking
公开(公告)号：AU2002354397A1
公开(公告)日：2003-06-23
申请号：AU2002354397
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： PRUIJN GERARDUS JOZEF MARIA , VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：AU741850B2
公开(公告)日：2001-12-13
申请号：AU4970797
申请日：1997-11-14
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
IPC: C07K7/08 , C07K14/47 , C07K16/18 , C12P21/08 , G01N33/564
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：HK1072805A1
公开(公告)日：2005-09-09
申请号：HK05102287
申请日：2005-03-15
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
IPC: G01N20060101 , C07K20060101 , C07K7/06 , C07K7/08 , C07K7/54 , C07K14/47 , G01N33/53 , G01N33/564
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：AU4970797A
公开(公告)日：1998-06-10
申请号：AU4970797
申请日：1997-11-14
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
IPC: C07K7/08 , C07K14/47 , C07K16/18 , C12P21/08 , G01N33/564
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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公开(公告)号：NL1004539C2
公开(公告)日：1998-05-20
申请号：NL1004539
申请日：1996-11-15
Applicant: STICHTING SCHEIKUNDIG ONDERZOE , STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , SCHELLEKENS GERARDUS ANTONIUS , RAATS JOZEF MARIA HENDRIK , HOET RENE MICHAEL ANTONIUS
Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
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