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1.发明申请METHOD OF DETECTING AUTOANTIBODIES FROM PATIENTS SUFFERING FROM RHEUMATOID ARTHRITIS, A PEPTIDE AND AN ASSAYKIT 审中-公开从患有炎热性疾病的患者中检测自身抗体的方法，肽和测定试剂
公开(公告)号：WO03050542A2
公开(公告)日：2003-06-19
申请号：PCT/NL0200815
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP , VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
CPC classification number: G01N33/564 , C07K7/08 , C07K7/52 , C07K7/64 , C07K14/4713 , G01N2410/00 , G01N2800/102 , Y10S435/973 , Y10S435/975 , Y10S530/806
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
Abstract translation: 本发明涉及从患有类风湿性关节炎的患者中检测自身抗体的方法。 为此，根据本发明，使用至少两个肽单元，其中至少一个肽单元包含不衍生自（pro）填充蛋白，纤维蛋白，纤维蛋白原，波形蛋白，细胞角蛋白1和细胞角蛋白9的部分，哪个肽单元 包含基序XG和包含基序XnonG的肽单元，其中X是瓜氨酸或其类似物，而nonG是除甘氨酸以外的氨基酸。
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公开(公告)号：HK1072805A1
公开(公告)日：2005-09-09
申请号：HK05102287
申请日：2005-03-15
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VENROOIJ WALTHERUS JACOBUS WIL , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
IPC: G01N20060101 , C07K20060101 , C07K7/06 , C07K7/08 , C07K7/54 , C07K14/47 , G01N33/53 , G01N33/564
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：CA2489167A1
公开(公告)日：2003-06-19
申请号：CA2489167
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： PRUIJN GERARDUS JOZEF MARIA , VAN VENROOIJ WALTHERUS JACOBUS , VAN BOEKEL MARTINUS ADRIANUS M , DRIJFHOUT JAN WOUTER
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention , at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glyci ne.
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公开(公告)号：BRPI0214872B1
公开(公告)日：2016-12-13
申请号：BRPI0214872
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： PRUIJN GERARDUS JOZEF MARIA , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA VAN , VENROOIJ WALTHERUS JACOBUS WILHELMUS VAN
Abstract: "métodos de detectar auto-anticorpos de pacientes sofrendo de artrite rumatóide, peptídeo e kit de ensaio". a presente invenção refere-se ao método de detectar auto-anticorpos de pacientes sofrendo de artrite reumatóide. para esta finalidade, de acordo com a invenção, pelo menos duas unidades peptídicas são usadas, das quais pelo menos uma unidade peptídica compreende uma parte não derivada de (pro)filagrina, fibrina, fibrinogênio, vimentina, citoceratina 1 e citoceratina 9, e unidade peptídica esta que compreende o motivo xg, e uma unidade peptídica compreendendo o motivo xnong, em que x é uma citrulina ou um análogo da mesma, e nong é um aminoácido diferente da glicina.
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公开(公告)号：CA2708463C
公开(公告)日：2015-08-11
申请号：CA2708463
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
IPC: C07K7/08 , C07K7/06 , C07K7/54 , C07K7/64 , C07K14/47 , C40B30/04 , G01N33/53 , G01N33/564 , G01N33/68
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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Patent Agency Ranking
公开(公告)号：AT329267T
公开(公告)日：2006-06-15
申请号：AT02786237
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：NL1019540C2
公开(公告)日：2003-07-01
申请号：NL1019540
申请日：2001-12-11
Applicant: STICHTING TECH WETENSCHAPP
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公开(公告)号：CA2489167C
公开(公告)日：2010-08-10
申请号：CA2489167
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：ES2266603T3
公开(公告)日：2007-03-01
申请号：ES02786237
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Abstract: Una unidad peptídica que comprende una secuencia seleccionada del grupo que consiste en péptido 0002-27 HQKRGCitGWSRAA, péptido 0002-29 HQRRVCitGWSRAA, péptido 0002-31 HQRRTCitGGSRAA, péptido 0002-32 HQRKWCitGASRAA, péptido 0002- 36 HQFRFCitGCitSRAA, péptido 0002-37 HQKWRCitGRSCitAA y péptido 0002-63 HQFRFCitGWSRAA.
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公开(公告)号：SI1456662T1
公开(公告)日：2006-12-31
申请号：SI200230389
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
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