FLEXIBLE PENETRATING CORTICAL MULTIELECTRODE ARRAYS, SENSOR DEVICES AND MANUFACTURING METHODS
    3.
    发明申请
    FLEXIBLE PENETRATING CORTICAL MULTIELECTRODE ARRAYS, SENSOR DEVICES AND MANUFACTURING METHODS 审中-公开
    柔性穿透多孔电极阵列,传感器装置和制造方法

    公开(公告)号:WO2016022906A1

    公开(公告)日:2016-02-11

    申请号:PCT/US2015/044185

    申请日:2015-08-07

    Abstract: A preferred conformal penetrating multi electrode array includes a plastic substrate that is flexible enough to conform to cortical tissue. A plurality of penetrating semiconductor micro electrodes extend away from a surface of the flexible substrate and are stiff enough to penetrate cortical tissue. Electrode lines are encapsulated at least partially within the flexible substrate and electrically connected to the plurality of penetrating semiconductor microelectrodes. The penetrating semiconductor electrodes preferably include pointed metal tips. A preferred method of fabrication permits forming stiff penetrating electrodes on a substrate that is very flexible, and providing electrical connection to electrode lines within the substrate.

    Abstract translation: 优选的共形穿透性多电极阵列包括足够柔性以符合皮质组织的塑料基底。 多个穿透半导体微电极远离柔性基底的表面延伸并且足够硬以穿透皮质组织。 电极线至少部分地封装在柔性基板内并电连接到多个穿透半导体微电极。 穿透半导体电极优选地包括尖锐的金属尖端。 优选的制造方法允许在非常柔性的基底上形成刚性穿透电极,并且提供与衬底内的电极线的电连接。

    MULTI-HUNDRED OR THOUSAND CHANNEL ELECTRODE ELECTROPHYSIOLOGICAL ARRAY AND FABRICATION METHOD

    公开(公告)号:WO2022192560A1

    公开(公告)日:2022-09-15

    申请号:PCT/US2022/019778

    申请日:2022-03-10

    Abstract: A flexible electrode array with hundreds or thousands channels for clinical use includes an array of at least hundreds of electrodes on a flexible biocompatible polymer substrate. Perfusion through holes are provided through the substrate. Individual elongate leads connect to each of the electrodes, the elongate lead connections being supported by the flexible biocompatible polymer substrate and extending away from the array. Flexible biocompatible polymer insulates the individual elongate lead connections and supporting the array. An interposer with individual channel connections is conductively bonded to the individual elongate lead connections. Sterile bag packaging encloses a portion of the interposer, where the outer side of the package including the array and individual elongate lead is sterile while the inner side of the packaging is non-sterile. The portion interposer inside the package is configured to connect to a circuit board within the packaging.

    TACTILE SENSOR ARRAY ON FLEXIBLE SUBSTRATE WITH PIEZOELECTRIC TFT TACTILE SENSOR

    公开(公告)号:WO2022035659A1

    公开(公告)日:2022-02-17

    申请号:PCT/US2021/044520

    申请日:2021-08-04

    Abstract: A flexible thin film transistor tactile sensor includes a piezoelectric semiconductor thin film channel of material whose conductivity can be electrostatically controlled connected with source and drain metals and sandwiched between bottom and top thin film insulators and at least one of a bottom and top gate metal, the sensor being supported on a flexible substrate. The piezoelectric property of the used material transduces pressure to electronic charge. The semiconductor property of the used material permits electrostatic modulation of the conductivity in TFT device architecture such that the device can be switched on and off. Transistor action provides gain for input signals, i.e., a modulation of the gate voltage induces strong current change between the source and drain, which can be leveraged to amplify the response to input pressure. The transistor forms the basis for sensor arrays, which are readily scalable to large size.

    ADDRESSABLE VERTICAL NANOWIRE PROBE ARRAYS AND FABRICATION METHODS
    7.
    发明申请
    ADDRESSABLE VERTICAL NANOWIRE PROBE ARRAYS AND FABRICATION METHODS 审中-公开
    可寻址的垂直纳米探针阵列和制造方法

    公开(公告)号:WO2017127551A1

    公开(公告)日:2017-07-27

    申请号:PCT/US2017/014143

    申请日:2017-01-19

    Abstract: A nanowire probe sensor array including a substrate with a metal pattern thereon. An array of semiconductor vertical nanowire probes extends away from the substrate, and at least some of probes, and preferably all, are individually electrically addressed through the metal pattern. The metal pattern is insulated with dielectric, and base and stem portions of the nanowires are also preferably insulated. A fabrication process patterns metal connections on a substrate. A semiconductor substrate is bonded to the metal pattern. The semiconductor substrate is etched to form the neural nanowire probes that are bonded to the metal pattern. Dielectric is then deposited to insulate the metal pattern.

    Abstract translation: 纳米线探针传感器阵列,包括其上具有金属图案的衬底。 半导体垂直纳米线探针的阵列从衬底延伸出来,并且探针中的至少一些,并且优选地全部通过金属图案单独电寻址。 金属图案用电介质绝缘,并且纳米线的基部和杆部也优选地绝缘。 制造工艺在衬底上图案化金属连接。 半导体衬底结合到金属图案。 蚀刻半导体衬底以形成结合到金属图案的神经纳米线探针。 然后沉积电介质以绝缘金属图案。

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