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29 records (took 0.026 seconds)

    1.
    发明专利
    未知

    公开(公告)号：DE69230125T2

    公开(公告)日：2000-02-03

    申请号：DE69230125

    申请日：1992-04-23

    Applicant: TORAY INDUSTRIES

    Inventor： SHIBAYAMA KATSUHIRO ,  MAKINO TETSUYA ,  IMAOKA TAKAYUKI ,  KATOU TETSUYA ,  KANEKO MASAYUKI

    IPC: A61K31/41 ,  A61K31/495 ,  A61K31/55 ,  C07D487/04 ,  C07D519/00

    Abstract: A novel tricyclic triazole derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, useful as an antiinflammatory, antiallergic and anti-PAF drug, and a process for the production thereof. In formula (I), R represents hydrogen, lower alkyl or C to C psi cycloalkyl; R and R represent each hydrogen, lower alkyl, lower alkoxy or halogen; W represents C = O or CR4R5 wherein R4 and R5 represent each hydrogen or lower alkyl; A represents C to C psi saturated or unsaturated alkylene which may contain a heteroatom; 1 represents 0 to 2; n represents 1 to 3; symbol -- represents a single or double bond; Y represents N or C; and Z represents C(B)Ar Ar (wherein B represents hydrogen, hydroxy or methoxy, and Ar and Ar represent each hydrogen or (un)substituted aryl), CAr Ar (wherein Ar and Ar are each as defined above), O-CHAr Ar (wherein Ar and Ar are each as defined above) or a condensed aromatic ring.

    3.
    发明专利
    未知

    公开(公告)号：ES2139595T3

    公开(公告)日：2000-02-16

    申请号：ES92909493

    申请日：1992-04-23

    Applicant: TORAY INDUSTRIES

    Inventor： SHIBAYAMA KATSUHIRO ,  MAKINO TETSUYA ,  IMAOKA TAKAYUKI ,  KATOU TETSUYA ,  KANEKO MASAYUKI

    IPC: A61K31/41 ,  A61K31/495 ,  A61K31/55 ,  C07D487/04 ,  C07D519/00

    Abstract: A novel tricyclic triazole derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, useful as an antiinflammatory, antiallergic and anti-PAF drug, and a process for the production thereof. In formula (I), R represents hydrogen, lower alkyl or C to C psi cycloalkyl; R and R represent each hydrogen, lower alkyl, lower alkoxy or halogen; W represents C = O or CR4R5 wherein R4 and R5 represent each hydrogen or lower alkyl; A represents C to C psi saturated or unsaturated alkylene which may contain a heteroatom; 1 represents 0 to 2; n represents 1 to 3; symbol -- represents a single or double bond; Y represents N or C; and Z represents C(B)Ar Ar (wherein B represents hydrogen, hydroxy or methoxy, and Ar and Ar represent each hydrogen or (un)substituted aryl), CAr Ar (wherein Ar and Ar are each as defined above), O-CHAr Ar (wherein Ar and Ar are each as defined above) or a condensed aromatic ring.

    4.
    发明专利
    未知

    公开(公告)号：FI925833A

    公开(公告)日：1992-12-22

    申请号：FI925833

    申请日：1992-12-22

    Applicant: TORAY INDUSTRIES

    Inventor： SHIBAYAMA KATSUHIRO ,  MAKINO TETSUYA ,  IMAOKA TAKAYUKI ,  KATOU TETSUYA ,  KANEKO MASAUYKI

    IPC: A61K31/41 ,  A61K31/495 ,  A61K31/55 ,  C07D487/04 ,  C07D519/00

    Abstract: A novel tricyclic triazole derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, useful as an antiinflammatory, antiallergic and anti-PAF drug, and a process for the production thereof. In formula (I), R represents hydrogen, lower alkyl or C to C psi cycloalkyl; R and R represent each hydrogen, lower alkyl, lower alkoxy or halogen; W represents C = O or CR4R5 wherein R4 and R5 represent each hydrogen or lower alkyl; A represents C to C psi saturated or unsaturated alkylene which may contain a heteroatom; 1 represents 0 to 2; n represents 1 to 3; symbol -- represents a single or double bond; Y represents N or C; and Z represents C(B)Ar Ar (wherein B represents hydrogen, hydroxy or methoxy, and Ar and Ar represent each hydrogen or (un)substituted aryl), CAr Ar (wherein Ar and Ar are each as defined above), O-CHAr Ar (wherein Ar and Ar are each as defined above) or a condensed aromatic ring.

    METHOD OF PRODUCING PLATINUM (II) COMPLEX
    6.
    发明专利
    METHOD OF PRODUCING PLATINUM (II) COMPLEX 未知

    公开(公告)号：CA2193391A1

    公开(公告)日：1996-10-31

    申请号：CA2193391

    申请日：1996-04-25

    Applicant: TORAY INDUSTRIES

    Inventor： KAWAI HIDEKI ,  IMAOKA TAKAYUKI ,  HATA GO

    IPC: C07C209/84 ,  C07C209/88 ,  C07C211/36 ,  C07D307/60 ,  C07F15/00 ,  C07C209/82

    Abstract: A process for the production of a platinum (II) complex represented by general formula (A) which comprises reacting a dichloroplatinum (II) complex of general formula (B) with a tetronic acid derivative of general formula (C) in the coexistence of a silver salt and a barium salt. In the formulae (A) and (C), R1 represents lower (C1-3) hydrocarbon group; and R2 and R3 represent each hydrogen or lower (C1-3) hydrocarbon group. Another process for producing in a high yield trans-1,2-diaminocyclohexane having a high optical purity which comprises mixing trans-1,2-diaminocyclohexane, which is the starting material in the production of a platinum (II) complex, with an acid having no optically active site followed by the recrystallization from a water-soluble organic solvent optionally mixed with water.

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