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    ANALYSIS CHIP AND ANALYSIS METHOD
    1.
    发明专利
    ANALYSIS CHIP AND ANALYSIS METHOD 未知

    公开(公告)号：CA2671866A1

    公开(公告)日：2008-07-31

    申请号：CA2671866

    申请日：2008-01-23

    Applicant: TORAY INDUSTRIES

    Inventor： NOMURA OSAMU ,  MURAO YASUO ,  NOBUMASA HITOSHI ,  KURODA TOSHIHIKO

    IPC: G01N33/53 ,  C12M1/00 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/543 ,  G01N37/00

    Abstract: An analysis chip which has a baseboard having a selectively binding subst ance immobilized on the surface thereof, a covering member bonded to this ba seboard and fine particles contained or injected in a movable state within a space that is formed between the baseboard and the covering member, wherein the surface of the fine particles is coated with a surfactant. Owing to thi s construction, it is possible to prevent the formation of bubbles inhibitin g a selective reaction between a test substance and the selectively binding substance having been immobilized so that data variation and lowering in the sensitivity can be regulated and the reproducibility of the measurement can be elevated.

    Analysis chip and analysis method
    2.
    发明专利
    Analysis chip and analysis method 未知

    公开(公告)号：AU2008208342A1

    公开(公告)日：2008-07-31

    申请号：AU2008208342

    申请日：2008-01-23

    Applicant: TORAY INDUSTRIES

    Inventor： KURODA TOSHIHIKO ,  NOBUMASA HITOSHI ,  MURAO YASUO ,  NOMURA OSAMU

    IPC: G01N33/53 ,  C12M1/00 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/543 ,  G01N37/00

    Abstract: This invention is directed to an analysis chip comprising a substrate having a surface on which a selective binding substance is immobilized; a cover member adhered to the substrate; and particles movably contained or injected in a void between the substrate and the cover member; wherein the surfaces of the particles are coated with a surfactant. By this invention, generation of bubbles which inhibit the selective reaction between the test substance and the immobilized selective binding substance is suppressed, thereby reducing the deviation of data, suppressing the lowering of sensitivity, and promoting the reproducibility of the measurement.

    ANALYSIS CHIP AND ANALYSIS METHOD
    3.
    发明专利
    ANALYSIS CHIP AND ANALYSIS METHOD 未知

    公开(公告)号：CA2671866C

    公开(公告)日：2014-03-25

    申请号：CA2671866

    申请日：2008-01-23

    Applicant: TORAY INDUSTRIES

    Inventor： NOMURA OSAMU ,  KURODA TOSHIHIKO ,  NOBUMASA HITOSHI ,  MURAO YASUO

    IPC: C40B60/12 ,  C12Q1/68 ,  C40B30/04 ,  C40B40/00 ,  G01N33/543

    Abstract: An analysis chip which has a baseboard having a selectively binding substance immobilized on the surface thereof, a covering member bonded to this baseboard and fine particles contained or injected in a movable state within a space that is formed between the baseboard and the covering member, wherein the surface of the fine particles is coated with a surfactant. Owing to this construction, it is possible to prevent the formation of bubbles inhibiting a selective reaction between a test substance and the selectively binding substance having been immobilized so that data variation and lowering in the sensitivity can be regulated and the reproducibility of the measurement can be elevated.

    6.
    发明专利
    未知

    公开(公告)号：DE3874901T2

    公开(公告)日：1993-04-22

    申请号：DE3874901

    申请日：1988-02-11

    Applicant: TORAY INDUSTRIES

    Inventor： MURAO YASUO ,  HOSAKA SHUNTARO

    IPC: G01N33/50 ,  C07H21/04 ,  C07K14/02 ,  C12N15/09 ,  C12N15/10 ,  C12Q1/68 ,  C12N15/11 ,  C12P19/34

    Abstract: Discolsed is a process of preparing a single-stranded DNA. In the first step of the process of the present invention, a single-stranded DNA containing a template DNA region is provided. Then a terminating structure which terminates the extension of DNA chain which is to be formed using the template DNA as a template in a later step is introduced at the 5' end portion of the template DNA. Then one or more primers are hybridized with one or more portion of the template DNA. Therafter, the primer is extended utilizing the template DNA as a template. Finally, the single-stranded DNA formed by the extension of the primer is separated and recovered.

    7.
    发明专利
    未知

    公开(公告)号：DE3874901D1

    公开(公告)日：1992-11-05

    申请号：DE3874901

    申请日：1988-02-11

    Applicant: TORAY INDUSTRIES

    Inventor： MURAO YASUO ,  HOSAKA SHUNTARO

    IPC: G01N33/50 ,  C07H21/04 ,  C07K14/02 ,  C12N15/09 ,  C12N15/10 ,  C12Q1/68 ,  C12N15/11 ,  C12P19/34

    Abstract: Discolsed is a process of preparing a single-stranded DNA. In the first step of the process of the present invention, a single-stranded DNA containing a template DNA region is provided. Then a terminating structure which terminates the extension of DNA chain which is to be formed using the template DNA as a template in a later step is introduced at the 5' end portion of the template DNA. Then one or more primers are hybridized with one or more portion of the template DNA. Therafter, the primer is extended utilizing the template DNA as a template. Finally, the single-stranded DNA formed by the extension of the primer is separated and recovered.

    Analysis chip and analysis method
    9.
    发明专利
    Analysis chip and analysis method 未知

    公开(公告)号：AU2008208342B2

    公开(公告)日：2013-02-07

    申请号：AU2008208342

    申请日：2008-01-23

    Applicant: TORAY INDUSTRIES

    Inventor： NOBUMASA HITOSHI ,  KURODA TOSHIHIKO ,  MURAO YASUO ,  NOMURA OSAMU

    IPC: G01N33/53 ,  C12M1/00 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/543 ,  G01N37/00

    Abstract: An analysis chip which has a baseboard having a selectively binding substance immobilized on the surface thereof, a covering member bonded to this baseboard and fine particles contained or injected in a movable state within a space that is formed between the baseboard and the covering member, wherein the surface of the fine particles is coated with a surfactant. Owing to this construction, it is possible to prevent the formation of bubbles inhibiting a selective reaction between a test substance and the selectively binding substance having been immobilized so that data variation and lowering in the sensitivity can be regulated and the reproducibility of the measurement can be elevated.

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