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    Procedimiento de agitación de una solución
    2.
    发明专利
    Procedimiento de agitación de una solución 未知

    公开(公告)号：ES2382475T3

    公开(公告)日：2012-06-08

    申请号：ES05720981

    申请日：2005-03-17

    Applicant: TORAY INDUSTRIES

    Inventor： TAKII YUKI ,  NAGINO KUNIHISA ,  NAKAMURA FUMIO ,  NOBUMASA HITOSHI

    IPC: G01N35/02 ,  B01F33/40 ,  C12M1/02 ,  C12N15/09 ,  C12Q1/68 ,  G01N1/36 ,  G01N33/53 ,  G01N35/00 ,  G01N37/00

    Abstract: Procedimiento de agitación de una solución, que comprende poner en contacto una sustancia de enlace selectivo (1) inmovilizada sobre la superficie de un portador (3) con una solución contenida en un recipiente (4) que contiene un analito que reacciona con dicha sustancia de enlace selectivo (1), y mezclar partículas finas (2) en la solución que contiene dicho analito, y mover dichas partículas finas (2) sin permitir el contacto de las mismas con la superficie sobre la que se ha inmovilizado la sustancia de enlace selectivo, caracterizado porque el portador (3) o el recipiente para la solución (4) tiene una estructura tal que las partículas finas (2) no se ponen en contacto con la superficie sobre la que se ha inmovilizado la sustancia de enlace selectivo y la anchura mínima de las partículas finas (2) es mayor que la distancia mínima entre la superficie sobre la que se ha inmovilizado la sustancia de enlace selectivo y el recipiente para la solución (4).

    3.
    发明专利
    未知

    公开(公告)号：AT546738T

    公开(公告)日：2012-03-15

    申请号：AT05720981

    申请日：2005-03-17

    Applicant: TORAY INDUSTRIES

    Inventor： TAKII YUKI ,  NAGINO KUNIHISA ,  NAKAMURA FUMIO ,  NOBUMASA HITOSHI

    IPC: G01N35/02 ,  B01F33/40 ,  C12M1/02 ,  C12N15/09 ,  C12Q1/68 ,  G01N1/36 ,  G01N33/53 ,  G01N35/00 ,  G01N37/00

    Abstract: The method of stirring a solution according to the present invention is a method of stirring a solution comprising contacting a selective binding substance immobilized on the surface of a carrier with a solution containing an analyte substance reactive with the selective binding substance, and mixing the fme particles or air bubbles into the solution containing an analyte substance, and moving the fine particles or air bubbles without allowing contact thereof with the selective binding substance-immobilized surface. The present invention provides a stirring method that accelerates the reaction of a carrier-immobilized selective binding substance with an analyte substance and detects a trace amount of analyte at high signal intensity and high S/N ratio. The present invention enables diagnosis and examination in the clinical setting by using a selective binding substance-immobilized carrier such as DNA chip.

    METHOD OF STIRRING SOLUTION
    4.
    发明专利
    METHOD OF STIRRING SOLUTION 未知

    公开(公告)号：CA2559768C

    公开(公告)日：2014-01-07

    申请号：CA2559768

    申请日：2005-03-17

    Applicant: TORAY INDUSTRIES

    Inventor： TAKII YUKI ,  NAGINO KUNIHISA ,  NAKAMURA FUMIO ,  NOBUMASA HITOSHI

    IPC: G01N35/02 ,  B01F33/40 ,  C12M1/02 ,  C12N15/09 ,  C12Q1/68 ,  G01N1/36 ,  G01N33/53 ,  G01N35/00 ,  G01N37/00

    Abstract: The method of stirring a solution according to the present invention is a method of stirring a solution comprising contacting a selective binding substance immobilized on the surface of a carrier with a solution containing an analyte substance reactive with the selective binding substance, and mixing the fine particles or air bubbles into the solution containing an analyte substance, and moving the fine particles or air bubbles without allowing contact thereof with the selective binding substance-immobilized surface. The present invention provides a stirring method that accelerates the reaction of a carrier-immobilized selective binding substance with an analyte substance and detects a trace amount of analyte at high signal intensity and high S/N ratio. The present invention enables diagnosis and examination in the clinical setting by using a selective binding substance-immobilized carrier such as DNA chip.

    ANALYSIS CHIP, ANALYSIS METHOD AND METHOD FOR STIRRING SOLUTION
    5.
    发明专利
    ANALYSIS CHIP, ANALYSIS METHOD AND METHOD FOR STIRRING SOLUTION 未知

    公开(公告)号：CA2755709A1

    公开(公告)日：2010-09-23

    申请号：CA2755709

    申请日：2010-03-15

    Applicant: TORAY INDUSTRIES

    Inventor： BABA TOMO ,  TAKII YUKI

    IPC: G01N35/02 ,  C12M1/00 ,  C12N15/09 ,  G01N33/53 ,  G01N37/00

    Abstract: Provided is an analysis chip by which, in stirring a solution of a test substance with microparticles, the stirring efficiency of the test substance solution can be increased by using large-sized microparticles, without impairing a part of a support, on which a selectively bonding substance is fixed, by the migrating microparticles, to thereby increase the reaction efficiency with the selectively bonding substance. An analysis chip comprising: a support to the surface of which a selectively bonding substance is fixed; a container holding a solution containing a test substance capable of reacting with the selectively bonding substance; and microparticles for stirring the solution enclosed in a space formed by the support and the container, characterized in that a partition wall, which allows the permeation of the solution containing the test substance but not the microparticles, is provided in the space in such a manner as to separate the microparticles from the face on the support to which the selectively bonding substance is fixed; an analysis method using the analysis chip; and a method for stirring a solution.

    ANALYSIS CHIP, ANALYSIS METHOD AND METHOD FOR STIRRING SOLUTION
    6.
    发明专利
    ANALYSIS CHIP, ANALYSIS METHOD AND METHOD FOR STIRRING SOLUTION 未知

    公开(公告)号：SG174429A1

    公开(公告)日：2011-10-28

    申请号：SG2011066800

    申请日：2010-03-15

    Applicant: TORAY INDUSTRIES

    Inventor： BABA TOMO ,  TAKII YUKI

    Abstract: [Object] The invention provides an analysis chip by which the efficiency ofreaction with a selective binding substance is promoted by using particles having a large size to promote the efficiency of stirring of the test substance solution without5 damaging the portion of the carrier on which the selective binding substance is immobilized, by the moving particles when stirring the test substance solution with the particles.[Means of Solution] An analysis chip including a carrier having a surface on which a selective binding substance(s) is(are) immobilized; a vessel holding a solution1 0 containing a test substance(s) which react(s) with the selective binding substance(s); and particles for stirring the solution, the particles being sealed within a space formedbetween the carrier and the vessel; wherein a separator which allows passage therethrough of the solution containing the test substance(s) but does not allow passage therethrough of the particles is arranged in the space so as to separate the surface of the carrier on which the selective binding substance(s) is(are) immobilized and the particles; a method of analysis using the analysis chip; and a method of stirring a solution using the analysis chip.

    METHOD OF STIRRING SOLUTION
    7.
    发明专利
    METHOD OF STIRRING SOLUTION 未知

    公开(公告)号：CA2559768A1

    公开(公告)日：2005-09-29

    申请号：CA2559768

    申请日：2005-03-17

    Applicant: TORAY INDUSTRIES

    Inventor： TAKII YUKI ,  NAGINO KUNIHISA ,  NOBUMASA HITOSHI ,  NAKAMURA FUMIO

    IPC: G01N35/02 ,  B01F33/40 ,  C12M1/02 ,  C12N15/09 ,  C12Q1/68 ,  G01N1/36 ,  G01N33/53 ,  G01N35/00 ,  G01N37/00

    Abstract: The method of stirring a solution according to the present invention is a method of stirring a solution comprising contacting a selective binding substance immobilized on the surface of a carrier with a solution containing an analyte substance reactive with the selective binding substance, and mixing the fme particles or air bubbles into the solution containing an analyte substance, and moving the fine particles or air bubbles without allowing contact thereof with the selective binding substance-immobilized surface. The present invention provides a stirring method that accelerates the reaction of a carrier-immobilized selective binding substance with an analyte substance and detects a trace amount of analyte at high signal intensity and high S/N ratio. The present invention enables diagnosis and examination in the clinical setting by using a selective binding substance-immobilized carrier such as DNA chip.

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