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公开(公告)号：AU2018329887A1
公开(公告)日：2020-02-20
申请号：AU2018329887
申请日：2018-09-07
Inventor： UENO YOSHIYUKI , KASUYA JUNICHI , ARAKANE TORU , MATSUNAGA RYO , SEKIYA YUMIKO , UEDA YUJI , TERAMOTO KAZUO , OGASAWARA KAZUMASA
Abstract: An objective of the present disclosure is to provide an adsorption material that can selectively adsorb immunosuppressive leukocyte. The present disclosure provides an adsorption material for immunosuppressive leukocyte. The adsorption material includes a water-insoluble carrier to which at least one nitrogen-containing compound selected from a polyamine represented by a predetermined formula and aliphatic amines represented by predetermined formulae are bound. A form of the water-insoluble carrier is a fiber or a particle, a diameter of the fiber or the particle is 15 to 50 µm, and an arithmetic mean roughness of a surface of the water-insoluble carrier is 0.1 to 3.0 µm.
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公开(公告)号：CA3072044A1
公开(公告)日：2019-03-14
申请号：CA3072044
申请日：2018-09-07
Inventor： UENO YOSHIYUKI , KASUYA JUNICHI , ARAKANE TORU , MATSUNAGA RYO , SEKIYA YUMIKO , UEDA YUJI , TERAMOTO KAZUO , OGASAWARA KAZUMASA
Abstract: The purpose of the present invention is to provide an adsorption material capable of selectively adsorbing immunosuppressive leukocytes. The present disclosure provides an immunosuppressive leukocyte adsorption material containing a water-insoluble carrier to which is bonded one or more nitrogen-containing compounds selected from polyamines represented by a prescribed formula and aliphatic amines represented by a prescribed formula, the water-insoluble carrier having the form of fibers or particles, the diameter of the fibers or the particles being 15-50 µm, and the arithmetic mean roughness of the surface of the water-insoluble carrier being 0.1-3.0 µm.
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公开(公告)号：CA2487600C
公开(公告)日：2011-07-05
申请号：CA2487600
申请日：2003-04-03
Applicant: TORAY INDUSTRIES
Inventor： TERAMOTO KAZUO , YOSHIOKA TOSHIO , SHIMAGAKI MASAAKI , MATSUNASE TAKEO , WATANABE KOJI , UEDA YUJI , YAMAMOTO YOSHIKI
Abstract: An object of this invention is to provide an adsorbent for immunosuppressive substance, which adsorbent can highly efficiently and selectively adsorb an excessive immunosuppressive substance directly from the body fluid, can carry out extracorporeal perfusion safely and can be utilized in treatment of cancer. Such an excessive immunosuppressive substance may be involved in growth of cancer cells. An adsorbent for immunosuppressive substance of the invention includes a water-insoluble carrier and a hydrophilic amino group immobilized to the water-insoluble carrier. An extracorporeal perfusion column of the invention contains the adsorbent of the invention. A method for treating cancer of the invention carries out extracorporeal perfusion using the extracorporeal perfusion column of the invention.
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Patent Agency Ranking
公开(公告)号：CA2487600A1
公开(公告)日：2003-12-11
申请号：CA2487600
申请日：2003-04-03
Applicant: TORAY INDUSTRIES
Inventor： YOSHIOKA TOSHIO , MATSUNASE TAKEO , YAMAMOTO YOSHIKI , SHIMAGAKI MASAAKI , TERAMOTO KAZUO , WATANABE KOJI , UEDA YUJI
Abstract: An immunosuppressive substance adsorbent capable of selectively adsorbing excess immunosuppressive substances considered to be associated with the multiplication of carcinoma cells directly from humor at high efficiency and capable of safe extracorporeal circulation, which immunosuppressive substanc e adsorbent is useful for the treatment of cancer. In particular, an immunosuppressive substance adsorbent characterized by comprising a water insoluble carrier and, fixed thereto, hydrophilic amino groups. Further, the re is provided an extracorporeal circulation column characterized by being pack ed with the above adsorbent. Still further, there is provided a method of treating cancer characterized in that extracorporeal circulation is performe d by the use of the above extracorporeal circulation column.
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公开(公告)号：CA3073500A1
公开(公告)日：2019-03-14
申请号：CA3073500
申请日：2018-09-07
Inventor： KASUYA JUNICHI , MATSUNAGA RYO , UENO YOSHIYUKI , UEDA YUJI , TERAMOTO KAZUO , OGASAWARA KAZUMASA
Abstract: The purpose of the present disclosure is to provide an adsorbing material in which the physical strength of a carrier material is maintained and immunosuppressive proteins are efficiently adsorbed. The present disclosure provides an immunosuppressive-protein-adsorbing material that includes a water-insoluble carrier to which is bonded one or more nitrogen-containing compounds selected from polyamines represented by a prescribed formula and aliphatic amines represented by a prescribed formula, the total amount of amino groups on the water-insoluble carrier being greater than 0 µmol and no greater than 2500 µmol per gram, and the amount of primary amino groups on the water-insoluble carrier being no greater than 450 µmol per gram.
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6.发明公开IMMUNOSUPPRESSIVE SUBSTANCE ADSORBENT, EXTRACORPOREAL CIRCULATION COLUMN AND METHOD OF TREATING CANCER 审中-公开吸收剂免疫抑制剂，体外循环柱和方法治疗癌症的
公开(公告)号：EP1532993A4
公开(公告)日：2010-09-29
申请号：EP03756106
申请日：2003-04-03
Applicant: TORAY INDUSTRIES
Inventor： TERAMOTO KAZUO , YOSHIOKA TOSHIO , SHIMAGAKI MASAAKI , MATSUNASE TAKEO , WATANABE KOJI , UEDA YUJI , YAMAMOTO YOSHIKI
CPC classification number: B01J20/26 , A61M1/3679 , B01J20/261 , B01J20/262 , B01J20/265 , B01J20/28014 , B01J20/28016 , B01J20/28023 , B01J20/2803 , B01J20/28033 , B01J20/28045 , B01J20/28057 , B01J20/3092 , B01J20/321 , B01J20/3212 , B01J20/3217 , B01J20/3242 , B01J20/3251 , B01J20/3272 , B01J20/3293 , B01J2220/58 , B01J2220/60
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公开(公告)号：JPS62289746A
公开(公告)日：1987-12-16
申请号：JP13263186
申请日：1986-06-10
Applicant: TORAY INDUSTRIES , TORAY ENG CO LTD
Inventor： HAYASHIDA SHINICHIRO , UEDA YUJI
Abstract: PURPOSE:To easily measure the viscosity of fluid even when a high vacuum is produced in a fluid passage by opening a fluid intake passage in a trumpet shape in a projection surface in level with the internal wall surface of the fluid passage. CONSTITUTION:The projection surface 5 of a viscosity measuring instrument 1 is in level with the internal wall surface 3a of the fluid passage 3 and the fluid intake passage 16 which is open in the projection surface 5 is open in the trumpet shape, so even if a high vacuum is produced in the fluid passage 3, for example, the high-viscosity fluid flowing along the internal wall surface 3a enters the fluid intake passage 16 naturally and smoothly and is guided inward along the trumpet-shaped wall surface. The fluid is sucked forcibly by a gear pump 6 through communicating passage parts 21a and 21b to form a continuous flow. Thus, the fluid is sent to a viscometer 7 continuously and then the viscosity is measured continuously.
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公开(公告)号：JPH0641903B2
公开(公告)日：1994-06-01
申请号：JP13263186
申请日：1986-06-10
Applicant: TORAY INDUSTRIES , TORAY ENG CO LTD
Inventor： HAYASHIDA SHINICHIRO , UEDA YUJI
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