-
公开(公告)号：CA2757291C
公开(公告)日：2017-05-23
申请号：CA2757291
申请日：2010-03-30
Applicant: UBE INDUSTRIES
Inventor： HAGIHARA MASAHIKO , YONEDA KENJI , OKANARI EIJI , SHIGETOMI MANABU
IPC: A61K31/4427 , A61P27/06 , C07D213/72 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14
Abstract: Provided is a pharmaceutical composition for treating or preventing glaucoma, comprising a pyridylamino acetic acid compound represented by general formula (1) or a pharmacologically acceptable salt thereof as an active ingredient. In formula (1), R1, R2, and R3 each independently represent a hydrogen atom or the like; Y represents a group: -Q1-Q2 (wherein Q1 represents an arylene group or the like; and Q2 represents a group such as an aromatic ring group which may be substituted by a halogen atom or the like) or a dicyclic heteroaromatic ring which may be substituted by a halogen atom or the like; and Z represents a group such as an aromatic ring group which may be substituted by a halogen atom or the like.
-
公开(公告)号：HRP20160104T1
公开(公告)日：2016-03-25
申请号：HRP20160104
申请日：2016-01-29
Applicant: UBE INDUSTRIES
Inventor： HAGIHARA MASAHIKO , YONEDA KENJI , OKANARI EIJI , SHIGETOMI MANABU
IPC: C07D213/83 , A61K31/44 , A61K31/443 , A61K31/4439 , A61K31/444 , A61K31/501 , A61K31/506 , A61P27/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14
-
公开(公告)号：SG11201507976YA
公开(公告)日：2015-10-29
申请号：SG11201507976Y
申请日：2014-03-28
Applicant: UBE INDUSTRIES
Inventor： SHIBAKAWA NOBUHIKO , YONEDA KENJI , KATSUBE TETSUSHI , KANDA TOMOKO , ITO KOJI , YAMAMOTO KIYOSHI , IWASE NORIAKI , USHIYAMA SHIGERU
IPC: C07D213/74 , A61K31/4436 , A61K31/444 , A61P11/00 , A61P43/00 , C07D409/12
-
公开(公告)号：CO6670582A2
公开(公告)日：2013-05-15
申请号：CO13024408
申请日：2013-02-06
Applicant: DAIICHI SANKYO CO LTD , UBE INDUSTRIES
Inventor： NAKAMURA TSUYOSHI , NAMIKI HIDENORI , TERASAKA NAOKI , SHIMA AKIKO , HAGIHARA MASAHIKO , IWASE NORIAK , TAKATA KATSUNORI , KIKUCHI OSAMU , TSUBOIKE KAZUNARI , SETOGUCHI HIROYUKI , YONEDA KENJI , SUNAMOTO HIDETOSHI , ITO KOJI
IPC: A61K31/506 , A61K31/5377 , A61K31/541 , A61P3/04 , A61P3/06 , A61P9/10 , A61P43/00 , C07D401/14
Abstract: La presente invención proporciona un compuesto de piridina sustituida o una sal farmacológicamente aceptable del mismo que tiene excelente actividad de inhibición de CETP y es útil como un medicamento; la presente invención proporciona un compuesto representado por una fórmula general (I),
-
公开(公告)号：CZ300295B6
公开(公告)日：2009-04-15
申请号：CZ63099
申请日：1997-08-28
Applicant: SANKYO CO , UBE INDUSTRIES
Inventor： ASAI FUMITOSHI , SUGIDACHI ATSUHIRO , IKEDA TOSHIHIKO , KOIKE HIROYUKI , INOUE TERUHIKO , TAKATA KATSUNORI , IWAMURA RYO , KITA JUN-ICHIRO , YONEDA KENJI
IPC: C07D205/04 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/46 , A61P7/02 , A61P9/10 , C07D205/08 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D211/72 , C07D213/70 , C07D451/02 , C07D451/04
Abstract: Cyklický aminoderivát obecného vzorce I, kde R.sup.1.n. je substituovaný nebo nesubstituovaný fenyl R.sup.2.n. je substituovaný nebo nesubstituovaný alifatický C.sub.1-8.n.acyl, substituovaný nebo nesubstituovaný benzoyl nebo (C.sub.1-4.n.alkoxy)karbonyl a R.sup.3.n. je substituovaná 3- až 7clenná nasycená cyklická aminoskupina, která muže vytváret kondenzovaný kruh, nebo jeho farmaceuticky prijatelná sul, mají vynikající inhibicní úcinky na agregaci krevních desticek apod. a proto jsou použitelné jako terapeutické nebo preventivní lécivo proti embolii, trombóze nebo arteroskleróze.
-
Patent Agency Ranking
公开(公告)号：DE69731218D1
公开(公告)日：2004-11-18
申请号：DE69731218
申请日：1997-08-28
Applicant: SANKYO CO , UBE INDUSTRIES
Inventor： ASAI FUMITOSHI , SUGIDACHI ATSUHIRO , IKEDA TOSHIHIKO , KOIKE HIROYUKI , INOUE TERUHIKO , TAKATA KATSUNORI , IWAMURA RYO , KITA JUN-ICHIRO , YONEDA KENJI
IPC: A61K31/395 , A61K31/397 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/46 , A61P7/02 , A61P9/10 , C07D205/04 , C07D205/08 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D211/72 , C07D213/70 , C07D451/02 , C07D451/04
Abstract: Cyclic amine compounds of formula R1-R2CH-R3 (I) are new. R1 = phenyl optionally substituted by 1-4C alkyl, halo, fluoro-substituted 1-4C alkyl, 1-4C alkoxy, fluoro-substituted 1-4C alkoxy, cyano or nitro; R2 = 1-8C aliphatic acyl optionally substituted by halo, OH, 1-4C alkoxy or cyano; benzoyl optionally substituted by 1-4C alkyl, halo or 1-4C alkoxy; or (1-4C alkoxy)carbonyl; R3 = optionally condensed 3-7 membered cyclic saturated amino group substituted by optionally protected mercapto or 1-4C alkyl optionally substituted by optionally protected mercapto; CR4R5 (mercapto-protecting groups are 1-20C alkanoyl, 3-20C alkenoyl, benzoyl optionally substituted by 1-4C alkyl, halogen or 1-4C alkoxy); or (1-4C alkoxy)carbonyl; and R4, R5 = H, 1-4C alkyl, carboxy, (1-4C alkoxy) carbonyl, carbamoyl or mono- or di-(1-4C alkyl)carbamoyl.
-
公开(公告)号：NO312955B1
公开(公告)日：2002-07-22
申请号：NO990951
申请日：1999-02-26
Applicant: UBE INDUSTRIES
Inventor： ASAI FUMITOSHI , SUGIDACHI ATSUHIRO , IKEDA TOSHIHIKO , KOIKE HIROYUKI , INOUE TERUHIKO , TAKATA KATSUNORI , IWAMURA RYO , KITA JUN-ICHIRO , YONEDA KENJI
IPC: A61K31/395 , A61K31/397 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/46 , A61P7/02 , A61P9/10 , C07D205/04 , C07D205/08 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D211/72 , C07D213/70 , C07D451/02 , C07D451/04
Abstract: Cyclic amine compounds of formula R1-R2CH-R3 (I) are new. R1 = phenyl optionally substituted by 1-4C alkyl, halo, fluoro-substituted 1-4C alkyl, 1-4C alkoxy, fluoro-substituted 1-4C alkoxy, cyano or nitro; R2 = 1-8C aliphatic acyl optionally substituted by halo, OH, 1-4C alkoxy or cyano; benzoyl optionally substituted by 1-4C alkyl, halo or 1-4C alkoxy; or (1-4C alkoxy)carbonyl; R3 = optionally condensed 3-7 membered cyclic saturated amino group substituted by optionally protected mercapto or 1-4C alkyl optionally substituted by optionally protected mercapto; CR4R5 (mercapto-protecting groups are 1-20C alkanoyl, 3-20C alkenoyl, benzoyl optionally substituted by 1-4C alkyl, halogen or 1-4C alkoxy); or (1-4C alkoxy)carbonyl; and R4, R5 = H, 1-4C alkyl, carboxy, (1-4C alkoxy) carbonyl, carbamoyl or mono- or di-(1-4C alkyl)carbamoyl.
-
公开(公告)号：NO990951A
公开(公告)日：1999-04-27
申请号：NO990951
申请日：1999-02-26
Applicant: SANKYO CO , UBE INDUSTRIES
Inventor： ASAI FUMITOSHO , SUGIDACHI ATSUHIRO , IKEDA TOSHIHIKO , KOIKE HIROYUKI , INOUE TERUHIKO , TAKATA KATSUNORI , IWAMURA RYO , KITA JUN-ICHIRO , YONEDA KENJI
IPC: A61K31/395 , A61K31/397 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/46 , A61P7/02 , A61P9/10 , C07D205/04 , C07D205/08 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D211/72 , C07D213/70 , C07D451/02 , C07D451/04
CPC classification number: C07D213/70 , C07D205/04 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D451/02 , C07D451/04 , Y02P20/55
-
公开(公告)号：AU4031297A
公开(公告)日：1998-03-19
申请号：AU4031297
申请日：1997-08-28
Applicant: SANKYO CO , UBE INDUSTRIES
Inventor： ASAI FUMITOSHI , SUGIDACHI ATSUHIRO , IKEDA TOSHIHIKO , KOIKE HIROYUKI , INOUE TERUHIKO , TAKATA KATSUNORI , IWAMURA RYO , KITA JUN-ICHIRO , YONEDA KENJI
IPC: A61K31/395 , A61K31/397 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/46 , A61P7/02 , A61P9/10 , C07D205/04 , C07D205/08 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D211/72 , C07D213/70 , C07D451/02 , C07D451/04
Abstract: Cyclic amine compounds of formula R1-R2CH-R3 (I) are new. R1 = phenyl optionally substituted by 1-4C alkyl, halo, fluoro-substituted 1-4C alkyl, 1-4C alkoxy, fluoro-substituted 1-4C alkoxy, cyano or nitro; R2 = 1-8C aliphatic acyl optionally substituted by halo, OH, 1-4C alkoxy or cyano; benzoyl optionally substituted by 1-4C alkyl, halo or 1-4C alkoxy; or (1-4C alkoxy)carbonyl; R3 = optionally condensed 3-7 membered cyclic saturated amino group substituted by optionally protected mercapto or 1-4C alkyl optionally substituted by optionally protected mercapto; CR4R5 (mercapto-protecting groups are 1-20C alkanoyl, 3-20C alkenoyl, benzoyl optionally substituted by 1-4C alkyl, halogen or 1-4C alkoxy); or (1-4C alkoxy)carbonyl; and R4, R5 = H, 1-4C alkyl, carboxy, (1-4C alkoxy) carbonyl, carbamoyl or mono- or di-(1-4C alkyl)carbamoyl.
-
公开(公告)号：CA2263983A1
公开(公告)日：1998-03-05
申请号：CA2263983
申请日：1997-08-28
Applicant: UBE INDUSTRIES , SANKYO CO
Inventor： INOUE TERUHIKO , SUGIDACHI ATSUHIRO , KOIKE HIROYUKI , IKEDA TOSHIHIKO , TAKATA KATSUNORI , KITA JUN-ICHIRO , IWAMURA RYO , YONEDA KENJI , ASAI FUMITOSHI
IPC: A61K31/395 , A61K31/397 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/445 , A61K31/46 , A61P7/02 , A61P9/10 , C07D205/04 , C07D205/08 , C07D207/08 , C07D207/12 , C07D211/20 , C07D211/54 , C07D211/72 , C07D213/70 , C07D451/02 , C07D451/04
Abstract: Cyclic amine derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, excellent in the effect of inhibiting platelet aggregation and useful as a preventive or remedy for embolism, thrombosis or arteriosclerosis, wherein R1 represents optionally substituted phenyl; R2 represents optionally substituted C1-C8 acyl, optionally substituted benzoyl or C1-C4 alkoxycarbonyl; and R3 represents optionally fused, substituted three- to seven-membered cyclic saturated amino.
-
-
-
-
-
-
-
-
-
Search Results
56
records
(took 0.026 seconds)
