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公开(公告)号：DK0584082T3
公开(公告)日：2000-10-16
申请号：DK92906305
申请日：1992-01-28
Applicant: UNIV CALIFORNIA , COR THERAPEUTICS INC
Inventor： WOLF DAVID , WILLIAMS LEWIS T , FRETTO LARRY J , GIESE NEILL A , ESCOBEDO JAIME A , TOMLINSON JAMES E
IPC: A61K39/395 , A61K38/00 , C07K7/04 , C07K14/00 , C07K14/705 , C07K14/71 , C07K16/00 , C07K16/28 , C12N5/10 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12R1/91 , G01N33/53 , G01N33/566 , A01N1/02 , A61K37/02 , A61K38/18 , C07H15/12 , C07H17/00 , C07K3/00 , C07K13/00 , C07K14/475 , C07K15/00 , C07K17/00 , C12N5/00 , C12Q1/00 , C12Q1/68
Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.
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公开(公告)号：AT193553T
公开(公告)日：2000-06-15
申请号：AT92906305
申请日：1992-01-28
Applicant: COR THERAPEUTICS INC , UNIV CALIFORNIA
Inventor： ESCOBEDO JAIME A , WILLIAMS LEWIS T , WOLF DAVID , TOMLINSON JAMES E , FRETTO LARRY J , GIESE NEILL A
IPC: A61K39/395 , A61K38/00 , C07K7/04 , C07K14/00 , C07K14/705 , C07K14/71 , C07K16/00 , C07K16/28 , C12N5/10 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12R1/91 , G01N33/53 , G01N33/566 , C12Q1/68 , C07K14/475 , A61K38/18
Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.
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公开(公告)号：ES2147729T3
公开(公告)日：2000-10-01
申请号：ES92906305
申请日：1992-01-28
Applicant: COR THERAPEUTICS INC , UNIV CALIFORNIA
Inventor： ESCOBEDO JAIME A , WILLIAMS LEWIS T , WOLF DAVID , TOMLINSON JAMES E , FRETTO LARRY J , GIESE NEILL A
IPC: A61K39/395 , A61K38/00 , C07K7/04 , C07K14/00 , C07K14/705 , C07K14/71 , C07K16/00 , C07K16/28 , C12N5/10 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12R1/91 , G01N33/53 , G01N33/566 , C12Q1/68 , C07K14/475 , A61K38/18
Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.
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4.发明专利
公开(公告)号：AU709177B2
公开(公告)日：1999-08-26
申请号：AU5580496
申请日：1996-06-03
Applicant: UNIV CALIFORNIA , COR THERAPEUTICS INC
Inventor： ESCOBEDO JAIME A , WILLIAMS LEWIS T , WOLF DAVID , TOMLINSON JAMES E , FRETTO LARRY J , GIESE NEILL A
IPC: A61K39/395 , A61K38/00 , C07K7/04 , C07K14/00 , C07K14/705 , C07K14/71 , C07K16/00 , C07K16/28 , C12N5/10 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12R1/91 , G01N33/53 , G01N33/566
Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.
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公开(公告)号：WO02070707A2
公开(公告)日：2002-09-12
申请号：PCT/US0149168
申请日：2001-12-18
Applicant: CURAGEN CORP , COR THERAPEUTICS INC , PADIGARU MURALIDHARA , GERLACH VALERIE L , SMITHSON GLENNDA , STONE DAVID , BIN-YANG RUEY , CONLEY PAMELA , HART MATTHEW , TOMLINSON JAMES E , TOPPER JAMES N , KEKUDA RAMESH , CASMAN STACIE J , EDINGER SCHLOMIT , MACDOUGALL JOHN R
Inventor： PADIGARU MURALIDHARA , GERLACH VALERIE L , SMITHSON GLENNDA , STONE DAVID , BIN-YANG RUEY , CONLEY PAMELA , HART MATTHEW , TOMLINSON JAMES E , TOPPER JAMES N , KEKUDA RAMESH , CASMAN STACIE J , EDINGER SCHLOMIT , MACDOUGALL JOHN R
IPC: A61K38/00 , C07K14/705 , C12N15/12 , A61K31/7088 , A61K38/17 , A61K39/395 , C07K16/28 , C12N15/63 , C12Q1/68 , G01N33/50 , G01N33/53
CPC classification number: C07K14/705 , A61K38/00 , A61K2039/505
Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Abstract translation: 本文公开了编码G偶联蛋白 - 受体相关多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防与这些新型人核酸和蛋白质中的任一种相关的病症的治疗，诊断和研究方法。
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Patent Agency Ranking
公开(公告)号：WO0216599A2
公开(公告)日：2002-02-28
申请号：PCT/US0126510
申请日：2001-08-27
Applicant: CURAGEN CORP , COR THERAPEUTICS INC , BURGESS CATHERINE E , CONLEY PAMELA B , GROSSE WILLIAM M , HART MATTHEW , KEKUDA RAMESH , SHIMKETS RICHARD A , SPYTEK KIMBERLY A , SZEKERES EDWARD S JR , TOMLINSON JAMES E , TOPPER JAMES N , YANG RUEY BIN
Inventor： BURGESS CATHERINE E , CONLEY PAMELA B , GROSSE WILLIAM M , HART MATTHEW , KEKUDA RAMESH , SHIMKETS RICHARD A , SPYTEK KIMBERLY A , SZEKERES EDWARD S JR , TOMLINSON JAMES E , TOPPER JAMES N , YANG RUEY-BIN
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses tehrapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Abstract translation: 本文公开了编码新型多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体以及前述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防与这些新型人核酸和蛋白质中的任何一种相关的病症的治疗，诊断和研究方法。
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7.发明公开METHODS FOR PRODUCTION OF PURIFIED SOLUBLE TYPE B AND TYPE A HUMAN PLATELET-DERIVED GROWTH FACTOR RECEPTOR FRAGMENTS. 失效纯化溶剂型B和A型人类平板衍生生长因子受体片段的生产方法。
公开(公告)号：EP0619836A4
公开(公告)日：1996-12-04
申请号：EP93900825
申请日：1992-12-01
Applicant: COR THERAPEUTICS INC
Inventor： WOLF DAVID , TOMLINSON JAMES E
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8.发明公开
公开(公告)号：EP0584082A4
公开(公告)日：1994-08-24
申请号：EP92906305
申请日：1992-01-28
Applicant: COR THERAPEUTICS INC , ESCOBEDO JAIME A , WILLIAMS LEWIS T
Inventor： ESCOBEDO JAIME A , WILLIAMS LEWIS T , WOLF DAVID , TOMLINSON JAMES E , FRETTO LARRY J , GIESE NEILL A
IPC: A61K39/395 , A61K38/00 , C07K7/04 , C07K14/00 , C07K14/705 , C07K14/71 , C07K16/00 , C07K16/28 , C12N5/10 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12R1/91 , G01N33/53 , G01N33/566
CPC classification number: C07K16/2863 , A61K38/00 , C07K14/71 , C07K2319/00
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公开(公告)号：CA2294365A1
公开(公告)日：1999-01-14
申请号：CA2294365
申请日：1998-07-01
Applicant: COR THERAPEUTICS INC , UNIV WASHINGTON
Inventor： STROM DANIEL R , TOMLINSON JAMES E , HACKER BETH
Abstract: A DNA sequence encoding a human adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described.
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公开(公告)号：AU675924B2
公开(公告)日：1997-02-27
申请号：AU3236493
申请日：1992-12-01
Applicant: COR THERAPEUTICS INC
Inventor： WOLF DAVID , TOMLINSON JAMES E
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