公开(公告)号：AU2005219861B2

公开(公告)日：2011-08-11

申请号：AU2005219861

申请日：2005-02-28

Applicant: VERTEX PHARMA

Inventor： STUDLEY JOHN R ,  MICHAEL MORTIMORE ,  JEAN-DAMIEN CHARRIER ,  ALISTAIR RUTHERFORD ,  ADAM LOOKER ,  MICHAEL O'DONNELL ,  MARTIN TRUDEAU ,  SHARN RAMAYA ,  STEVEN DURRANT

IPC: C07D207/16 ,  A61K38/04 ,  A61K38/06 ,  C07D209/52 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D417/06 ,  C07D417/12 ,  C07K5/02 ,  C07K5/04

Abstract: The present invention provides a compound of formula (I): wherein the variables are as defined herein. The present invention also provides processes for preparing the compounds of formula (I), and intermediates thereof, pharmaceutical compositions comprising those compounds, and methods of using the compounds and compositions.

公开(公告)号：ZA200704971B

公开(公告)日：2008-09-25

申请号：ZA200704971

申请日：2005-12-15

Applicant: VERTEX PHARMA

Inventor： JEAN-DAMIEN CHARRIER ,  STEVEN DURRANT ,  SHARN RAMAYA ,  JUAN-MIGUEL JIMENEZ ,  ALISTAIR RUTHERFORD

IPC: A61K20090101 ,  A61P20090101 ,  C07D20090101