公开(公告)号：US20250067599A1

公开(公告)日：2025-02-27

申请号：US18721164

申请日：2022-12-19

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Ashwin PARTHASARATHY ,  Sadhu MOKA ,  Abdul Mohaimen SAFI

IPC: G01J3/433 ,  A61B5/026 ,  A61B5/145 ,  A61B5/1455 ,  G01J1/44 ,  G01J3/02 ,  G01J3/44

Abstract: Systems, methods, and apparatus for frequency domain diffuse correlation spectroscopy are provided. In some embodiments, the system comprises: an intensity modulated coherent light source; a photon counting detector; at least one hardware processor that is programmed to: cause the light source to emit light at a plurality of different intensity modulation frequencies toward a tissue sample; detect, for each of the plurality of different modulation frequencies, photon counts over a predetermined period of time; determine, for each of the plurality of modulation frequencies, a normalized intensity auto-correlation function; estimate a plurality of properties of the tissue sample using the plurality of intensity auto-correlation functions; and output at least one of the plurality of properties.