公开(公告)号：US20210088504A1

公开(公告)日：2021-03-25

申请号：US17109187

申请日：2020-12-02

Applicant: Tokyo University of Science Foundation

Inventor： Etsuko MIYAMOTO ,  Masaaki OZAWA

IPC: G01N33/50 ,  C07D239/49 ,  C07K5/00 ,  C12Q1/02 ,  A61K38/00 ,  C12N9/00 ,  C07K14/47 ,  C12N9/76 ,  C12P21/06

Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.

公开(公告)号：US20210040218A1

公开(公告)日：2021-02-11

申请号：US16991528

申请日：2020-08-12

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Yoichiro IWAKURA ,  Noriyuki Fujikado ,  Guangyu Ma

IPC: C07K16/28 ,  A61K31/737 ,  G01N33/50

Abstract: An object of the present invention is to find a ligand for a DCIR and to search for an agonist and an antagonist for the DCIR.
Specifically, disclosed are: a dendritic cell immunoreceptor agonist containing keratan sulfate-II (KS-II) as an active ingredient; an antibody against dendritic cell immunoreceptor, having a keratan sulfate-II-like dendritic cell immunoreceptor agonism; and an antibody against a dendritic cell immunoreceptor, having a keratan sulfate-II inhibitory dendritic cell immunoreceptor antagonism.

公开(公告)号：US10862127B2

公开(公告)日：2020-12-08

申请号：US15819452

申请日：2017-11-21

Applicant: FUJIFILM WAKO PURE CHEMICAL CORPORATION ,  TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Shinichi Komaba ,  Naoaki Yabuuchi ,  Zhen-ji Han ,  Takeo Sasaki ,  Shota Hashimoto ,  Kuniaki Okamoto ,  Tsuneaki Maesawa

IPC: H01M4/62 ,  C08G59/40 ,  C08L63/00 ,  H01M4/134 ,  H01M4/38 ,  C08G18/02 ,  H01B1/12 ,  C08F122/02 ,  H01M10/0525 ,  C08L33/02 ,  C08L79/00 ,  H01M10/052 ,  C08K5/00 ,  H01M4/02

Abstract: It is an object of the present invention to provide an electrode capable of maintaining superior capacity retention without destruction of an electrode structure, even in the case of using an active material including silicon.The present invention relates to “a binder for a lithium cell, the binder comprising polyacrylic acid cross-linked by a cross-linking agent selected from the compounds described in the general formulae [1] to [13] and the polymer described in the general formula [14] (provided that the one which includes a functional group-containing vinylidene fluoride-based polymer is excluded)”; a “composition for producing an electrode of a lithium cell, the composition comprising 1) an active material containing silicon, 2) a conductive assistant and 3) a cross-linked-type polyacrylic acid (provided that the one containing a functional group-containing vinylidene fluoride-based polymer is excluded)”; and an “electrode for a lithium cell, the electrode comprising 1) an active material containing silicon, 2) a conductive assistant, 3) a cross-linked-type polyacrylic acid, and 4) a current collector (provided that the one containing a functional group-containing vinylidene fluoride-based polymer is excluded)”.

公开(公告)号：US20200179901A1

公开(公告)日：2020-06-11

申请号：US16631595

申请日：2017-07-20

Applicant: Japan Blue Energy Co., Ltd. ,  Tokyo University of Science Foundation

Inventor： Naoki Dowaki ,  Mitsuo Kameyama ,  Kiyoshi Dowaki

IPC: B01J20/04 ,  B01J20/12 ,  B01D53/68 ,  C10K1/00

Abstract: The present invention provides a new hydrogen chloride removing agent that exhibits a good hydrogen chloride removal effect at a relatively low temperature. The present invention preferably provides a new hydrogen chloride removing agent for removing hydrogen chloride contained in a hydrogen-chloride-containing gas, such as a pyrolysis gas, a combustion exhaust gas, a dry distillation gas, etc., especially hydrogen chloride contained in a biomass pyrolysis gas. The present invention relates to a hydrogen chloride removing agent characterized by containing a mixture of a calcium carbonate and an imogolite and/or a synthetic imogolite, and relates to a method for removing, by using said hydrogen chloride removing agent, hydrogen chloride contained in a hydrogen-chloride-containing gas, especially hydrogen chloride contained in a biomass pyrolysis gas.

公开(公告)号：US10590966B2

公开(公告)日：2020-03-17

申请号：US15552777

申请日：2016-02-22

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Toshihiko Yoshimura

IPC: F15D1/00 ,  B23P17/00 ,  G21B3/00 ,  B23P17/04 ,  B08B3/10 ,  B08B3/12

Abstract: Provided are a method for generating mechanical and electrochemical cavitation, a method for changing the geometric shape and the electrochemical properties of a surface of a substance, a method for peeling off a rare metal using the generated mechanical and electrochemical cavitation, a mechanical and electrochemical cavitation generator, and a method for generating a nuclear fusion reaction of deuterium. In the method for generating mechanical and electrochemical cavitation, a water jet is jetted from a jetting nozzle immersed in water, and flow cavitation generated by the jetting of the water jet is irradiated with an ultrasonic wave to generate cavitation MFC having both a functional effect and an electrochemical effect.

公开(公告)号：US20190382425A1

公开(公告)日：2019-12-19

申请号：US15519279

申请日：2015-10-28

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Isamu SHIINA ,  Takayuki TONOI

IPC: C07F9/655

Abstract: Provided are: eushearilides; a method for producing eushearilides; a production intermediate; and a pharmaceutical composition containing eushearilides. By having the Wittig reaction process, Mukaiyama Aldol reaction process and Macrolactonizaion process serve as key processes, eushearilides represented by formula (I) are efficiently produced.

公开(公告)号：US10468676B2

公开(公告)日：2019-11-05

申请号：US14780833

申请日：2014-03-17

Applicant: Sumitomo Chemical Company, Limited ,  Tokyo University of Science Foundation

Inventor： Shinichi Komaba ,  Naoaki Yabuuchi ,  Masaya Yano ,  Satoru Kuze

IPC: H01M4/505 ,  H01M4/525 ,  H01M10/054 ,  H01M10/0569 ,  H01M2/16 ,  H01M4/02

Abstract: A positive electrode-active material is provided for use in a positive electrode for a sodium secondary cell and a sodium secondary cell. Also provided is a positive electrode for a sodium secondary cell and a sodium secondary cell having a high energy density. The positive electrode-active material for a sodium secondary cell includes a composite metal oxide, which has an α-NaFeO2 type crystal structure and is denoted by Formula (1) described below: Naa(FewNixMny-zTiz)O2  (1), wherein a is greater than or equal to 0.6 and less than or equal to 1.0, w is greater than 0 and less than 0.5, x is greater than 0 and less than 0.5, y is greater than 0.03 and less than or equal to 0.5, z is greater than or equal to 0.03 and less than 0.5, and w+x+y=1.0, and y>z.

公开(公告)号：US10454108B2

公开(公告)日：2019-10-22

申请号：US15575462

申请日：2016-05-20

Applicant: Umicore ,  Tokyo University of Science Foundation

Inventor： Shinichi Kumakura ,  Shinichi Komaba ,  Kei Kubota ,  Yoshiyuki Tahara

IPC: H01B1/06 ,  H01M4/525 ,  H01M4/505 ,  C01G45/12 ,  C01G53/00 ,  H01M10/054 ,  H01M10/058 ,  H01M4/02

Abstract: A sodium transition metal based cathode material for a rechargeable sodium battery, having a P2 orthorhombic layered bronze crystal structure with space group Cmcm, and having a composition NaxMyMn1-yLiy′AzO2 with 0.60 0.

公开(公告)号：US20190280299A1

公开(公告)日：2019-09-12

申请号：US16463789

申请日：2017-11-20

Applicant: Tokyo University of Science Foundation

Inventor： Shinichi KOMABA ,  Kei KUBOTA ,  Kuniko CHIHARA ,  Akihiro KATOGI

IPC: H01M4/58 ,  H01M10/054 ,  C01G31/00

Abstract: Provided is the positive electrode active material for a potassium ion battery according to the embodiment comprises a compound represented by Formula (1), in which M represents at least one element selected from the group consisting of V, Fe, Co, Ni, and Mn, and x represents a number from 0 to 1; and is a positive electrode for a potassium ion battery comprising the positive electrode active material for a potassium ion battery according to the embodiment, or a potassium ion battery comprising the positive electrode for a potassium ion battery. KMOxPO4F1-x  [Formula (1)]

公开(公告)号：US20190270765A1

公开(公告)日：2019-09-05

申请号：US16349438

申请日：2017-11-09

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Takeshi Wada ,  Tatsuya Saito ,  Yuka Ishii ,  Yohei Nukaga

IPC: C07H19/173 ,  C07H19/073 ,  C07H21/00 ,  C12N15/113

Abstract: Provided a polymerizable compound represented by the following Formula A-1 or Formula A-2: In Formula A-1 or Formula A-2, R1 represents an electron-donating group; n represents an integer from 1 to 5; R2 represents a hydrogen atom, a halogen atom, or —ORO, wherein RO represents a hydrogen atom, an alkyl group, or a protecting group of a hydroxy group; R3 represents a hydrogen atom or a protecting group of a hydroxy group; and X represents a structure represented by any one of Formula B-1 to Formula B-5.