公开(公告)号：US20070102364A1

公开(公告)日：2007-05-10

申请号：US11594238

申请日：2006-11-08

Applicant: Kenji Okada ,  Noriaki Seko ,  Masao Tamada

Inventor： Kenji Okada ,  Noriaki Seko ,  Masao Tamada

IPC: B01J39/00

CPC classification number: B01J45/00 ,  B01J20/26 ,  B01J20/265 ,  B01J20/28023

Abstract: To produce a bifunctional adsorbent capable of adsorption in the acidic region, a polymeric substrate is first exposed to a radiation and then a phosphonic acid group suitable for metal adsorption and a sulfonic acid group are introduced into the substrate by graft polymerization.

Abstract translation: 为了生产能够在酸性区域吸附的双官能吸附剂，首先将聚合物基材暴露于辐射下，然后通过接枝聚合将适合于金属吸附的膦酸基团和磺酸基团引入到基材中。

公开(公告)号：US20070093654A1

公开(公告)日：2007-04-26

申请号：US10576468

申请日：2004-10-20

Applicant: Katsumi Yabusaki

Inventor： Katsumi Yabusaki

IPC: C08B7/00

CPC classification number: C08B1/08 ,  B01J20/24 ,  B01J20/265 ,  B01J20/28023 ,  B01J20/28033 ,  B01J20/3078 ,  B01J20/3085 ,  B01J20/3092 ,  B01J20/3212 ,  B01J20/3242 ,  B01J20/3246 ,  B01J20/3248 ,  B01J2220/4825 ,  B01J2220/58 ,  C02F1/288 ,  C02F2101/20 ,  C08B5/00 ,  C08B15/06

Abstract: This invention relates to cellulose II phosphate which may be partly carbamidated, and also to a metal-adsorbing material making use of the same. This cellulose II phosphate efficiently adsorbs metal ions in a solution, and can be used as a metal-adsorbing material and in a metal-adsorbing system.

Abstract translation: 本发明涉及可部分为氨基甲酸酯化的纤维素II磷酸酯，也涉及利用其的金属吸附材料。 该纤维素II磷酸盐能有效地吸附溶液中的金属离子，并且可以用作金属吸附材料和金属吸附体系。

公开(公告)号：US07205361B2

公开(公告)日：2007-04-17

申请号：US10491144

申请日：2002-09-27

Applicant: Keisuke Mano ,  Kuniaki Shimbo

Inventor： Keisuke Mano ,  Kuniaki Shimbo

IPC: C08F16/12 ,  C08F265/02

CPC classification number: G01N30/482 ,  B01D15/325 ,  B01J20/261 ,  B01J20/265 ,  B01J20/267 ,  B01J20/285 ,  B01J20/287 ,  B01J2220/54 ,  C08G59/04 ,  C08G59/1427 ,  C08G2650/34 ,  C08L71/02 ,  C08L2205/05 ,  C08L2666/04

Abstract: A particulate hydrophobic polymer produced by reacting (A) a particulate crosslinked polymer having a hydroxyl group with (B) a crosslinkable epoxy compound, hydrolyzing the epoxy bonds, and then reacting the obtained compound having a hydroxyl group with (C) an epoxy compound having from 6 to 40 carbon atoms in total, a production process therefor, a column for reversed-phase liquid chromatography, and an analysis method using the column.By using the particulate hydrophobic polymer of the present invention having a remarkably high acid/alkali resistance, a sharp chromatogram for polycyclic aromatic compounds is obtainable with the swelling and shrinkage of the particulate polymer itself reduced and without reducing the column efficiency among various solvents even when the eluent in the column is variously exchanged.

Abstract translation: 通过使（A）具有羟基的颗粒状交联聚合物与（B）可交联环氧化合物反应，水解环氧键，然后使得到的具有羟基的化合物与（C）具有 总共6至40个碳原子，其制备方法，用于反相液相色谱的柱和使用该柱的分析方法。

公开(公告)号：US20060201883A1

公开(公告)日：2006-09-14

申请号：US10545875

申请日：2004-02-18

Applicant: William Hofmeister ,  David Wright

Inventor： William Hofmeister ,  David Wright

IPC: B29C67/20 ,  B01D61/00

CPC classification number: B29C67/202 ,  B01D15/34 ,  B01D39/1676 ,  B01D2239/10 ,  B01J20/26 ,  B01J20/265 ,  B01J20/28026 ,  B01J20/28095 ,  B01L3/06 ,  B01L3/502707 ,  B01L3/502761 ,  B01L7/54 ,  B01L2200/12 ,  B01L2300/0819 ,  B01L2300/0877 ,  B01L2300/0896 ,  B01L2300/1827 ,  B01L2300/185 ,  B81C1/00071 ,  B81C2201/034 ,  B82Y15/00 ,  B82Y30/00 ,  Y10T436/255

Abstract: Disclosed herein are polymer matrixes having nanoscale channels dispersed therein and to methods for preparing such matrixes. Also disclosed are uses of such polymer matrixes, such as for separating and analyzing materials. Still further, disclosed are devices that include such polymer matrixes.

Abstract translation: 本文公开了具有分散在其中的纳米级通道的聚合物基质和用于制备这种基质的方法。 还公开了这种聚合物基质的用途，例如用于分离和分析材料。 更进一步地，公开了包括这种聚合物基质的装置。

公开(公告)号：US20060175260A1

公开(公告)日：2006-08-10

申请号：US11053810

申请日：2005-02-09

Applicant: Henry Kolesinski ,  Robert Cooley

Inventor： Henry Kolesinski ,  Robert Cooley

IPC: B01D15/08

CPC classification number: B01J20/28033 ,  B01J20/26 ,  B01J20/265 ,  B01J20/28004 ,  B01J20/28023 ,  B01J20/28038 ,  B01J20/285 ,  B01J20/286 ,  B01J20/328 ,  B01J47/12

Abstract: There is described a chromatographic separation member including a substrate carrying on at least one surface a thin layer of a chromatographically active capture material. Also described is a chromatographic separation method for separating a component of interest from a fluid utilizing the chromatographic separation member.

Abstract translation: 描述了一种色谱分离构件，其包括在至少一个表面上承载有层析色谱活性捕获材料的薄层。 还描述了使用色谱分离构件从流体中分离感兴趣组分的色谱分离方法。

公开(公告)号：US20060118483A1

公开(公告)日：2006-06-08

申请号：US11332033

申请日：2006-01-13

Applicant: David Sherrington ,  Hanna Mouaziz ,  Karol Lacki

Inventor： David Sherrington ,  Hanna Mouaziz ,  Karol Lacki

IPC: B01D71/06

CPC classification number: B01D39/1653 ,  B01D67/0004 ,  B01D2325/08 ,  B01D2325/12 ,  B01J2/06 ,  B01J20/26 ,  B01J20/261 ,  B01J20/265 ,  B01J20/28004 ,  B01J20/28019 ,  B01J20/2803 ,  B01J20/28033 ,  B01J20/285

Abstract: The present invention relates to a method of preparing a separation medium starting with an aqueous solution of spherical and preferably functionalised primary particles of defined size, comprising the following steps: a) inverse suspension dispersing said aqueous solution of primary particles as droplets in oil; b) evaporation to remove said aqueous solution and fusion between particles to form spherical aggregates; c) size fractionation of aggregates from step b); and optionally d) repeating steps a) to c) an optional number of times to form progressively larger spherical aggregates. The invention also relates to a separation medium produced by this method. The present separation medium can be used in chromatography in the form of essentially spherical aggregates in packed or expanded bed columns or in the form of assembled aggregates on a support for filtration purposes.

Abstract translation: 本发明涉及一种由具有规定尺寸的球形和优选官能化的初级颗粒的水溶液制备分离介质的方法，包括以下步骤：a）将所述初级颗粒水溶液作为液滴分散在油中的反相悬浮液; b）蒸发以除去所述水溶液和颗粒之间的熔合物以形成球形聚集体; c）来自步骤b）的聚集体的尺寸分级; 和任选地d）重复步骤a）至c）任选次数以形成逐渐变大的球形聚集体。 本发明还涉及通过该方法制备的分离介质。 本发明的分离介质可以在填充或膨胀床柱中以基本上为球形的聚集体形式的层析中使用，或者在用于过滤目的的载体上以组装的聚集体的形式使用。

公开(公告)号：US07056858B2

公开(公告)日：2006-06-06

申请号：US11154214

申请日：2005-06-16

Applicant: Krishna M. R. Kallury ,  David C. Jones ,  Vipul J. Shah

Inventor： Krishna M. R. Kallury ,  David C. Jones ,  Vipul J. Shah

IPC: B01J20/26

CPC classification number: B01J20/3248 ,  B01J20/26 ,  B01J20/261 ,  B01J20/265 ,  B01J20/267 ,  B01J20/28033 ,  B01J20/285 ,  B01J20/3202 ,  B01J20/3242 ,  B01J2220/62 ,  B01J2220/64 ,  C08F8/30 ,  G01N1/405 ,  Y10T428/31855 ,  C08F12/00

Abstract: A polymeric sorbent that can be employed in the extraction and purification of polar and nonpolar molecules from a complex media (e.g. pharmaceuticals from biological matrices) by solid phase extraction (SPE). The sorbent exhibits a strong capacity for the retention of polar molecules and can facilitate the recovery of compounds possessing a range of polarities while furnishing clean extracts showing low ion suppression. The polymer is wettable and remains wetted over long periods of time.

公开(公告)号：US07056507B2

公开(公告)日：2006-06-06

申请号：US10458297

申请日：2003-06-11

Applicant: Eiji Ogino ,  Michio Nomura ,  Takashi Asahi ,  Shuichi Kaneko ,  Akito Sakai

Inventor： Eiji Ogino ,  Michio Nomura ,  Takashi Asahi ,  Shuichi Kaneko ,  Akito Sakai

IPC: A61K39/42 ,  C07K1/22 ,  B01D15/08

CPC classification number: A61M1/3633 ,  A61M1/3679 ,  A61M2205/7509 ,  B01J20/262 ,  B01J20/265 ,  B01J20/28078 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3219 ,  B01J20/3255 ,  B01J20/3274 ,  B01J2220/58 ,  Y10S530/81

Abstract: An adsorbent for removing hepatitis C virus which has the ability to adsorb HCV particles, particularly immune-complex HCV particles, from a patient's body blood safely and with high efficiency and high selectivity for enhancing the efficacy of interferon therapy, an HCV adsorption apparatus including said adsorbent, and a adsorbing method for removing HCV are provided.An adsorbent for removing hepatitis C virus which comprises a compound capable of adsorbing hepatitis C virus as immobilized on a water-insoluble carrier, an adsorption apparatus including said adsorbent, and an adsorbing method for removing HCV.

Abstract translation: 一种用于除去丙型肝炎病毒的吸附剂，其具有从患者身体血液中安全地并以高效率和高选择性安全地吸收HCV颗粒，特别是免疫复合物HCV颗粒的能力，以提高干扰素疗法的功效，HCV吸附装置包括所述 吸附剂和用于除去HCV的吸附方法。 一种用于除去丙型肝炎病毒的吸附剂，其包含能够吸附固定在水不溶性载体上的丙型肝炎病毒的化合物，包括所述吸附剂的吸附装置和用于除去HCV的吸附方法。

公开(公告)号：US20050222279A1

公开(公告)日：2005-10-06

申请号：US10517293

申请日：2003-06-18

Applicant: Anders Larsson ,  Ulrika Meyer ,  Kajsa Stridsberg Friden ,  Eva Von Heijne

Inventor： Anders Larsson ,  Ulrika Meyer ,  Kajsa Stridsberg Friden ,  Eva Von Heijne

IPC: B01J20/281 ,  B01D15/32 ,  B01D15/36 ,  B01D15/38 ,  B01J20/26 ,  B01J20/285 ,  B01J39/26 ,  B01J41/20 ,  C08B37/00 ,  C08G81/00 ,  C08J7/12 ,  G01N30/88 ,  C08J9/00

CPC classification number: B01J20/286 ,  B01D15/327 ,  B01D15/361 ,  B01D15/3804 ,  B01J20/26 ,  B01J20/265 ,  B01J20/285 ,  B01J20/3272 ,  B01J20/3274 ,  B01J39/26 ,  B01J41/20 ,  C08B37/00 ,  C08G81/00 ,  C08J7/12

Abstract: The present invention is a surface-modified base matrix comprised of a porous polymeric base matrix onto which branched hydrophilic polyhydroxy-functional polymers have been covalently attached, wherein the polyhydroxy-functional polymers are hyperbranched polymers presenting a degree of branching (DB) of at least about 0.2 and each polymer is tethered to the base matrix at two or more points. The present matrix can for example be a cross-linked carbohydrate material, such as agarose, and the hyperbranched hydrophilic polymer can e.g. be a copolymer of epichlorohydrin and a sugar. The invention also relates to a method of surface-modification of a porous base matrix by activating functional hydroxy groups thereon and contacting the activated matrix with a hydrophilic hyperbranched hydroxy-functional polymer.

Abstract translation: 本发明是由多孔聚合物基质基质组成的表面改性的基质基质，其上分支的亲水性多羟基官能聚合物已共价连接到其上，其中多羟基官能聚合物是具有至少一种支化度（DB）的超支化聚合物 约0.2，并且每个聚合物在两个或更多个点处连接到基础基质上。 本发明的基质可以例如是交联的碳水化合物材料，例如琼脂糖，并且超支化亲水性聚合物可以例如。 是表氯醇和糖的共聚物。 本发明还涉及通过在其上活化官能羟基并使活化的基质与亲水性超支化羟基官能聚合物接触来表面改性多孔基质基质的方法。

公开(公告)号：US20050211616A1

公开(公告)日：2005-09-29

申请号：US11050004

申请日：2005-02-03

Applicant: Anthony DiLeo ,  Justin McCue ,  Wilson Moya ,  Igor Quinones-Garcia ,  Neil Soice ,  Volkmar Thom ,  Sarah Yuan

Inventor： Anthony DiLeo ,  Justin McCue ,  Wilson Moya ,  Igor Quinones-Garcia ,  Neil Soice ,  Volkmar Thom ,  Sarah Yuan

IPC: B01D15/08 ,  B01J20/28 ,  B01J20/286 ,  B01J20/32

CPC classification number: B01J20/286 ,  B01J20/262 ,  B01J20/265 ,  B01J20/267 ,  B01J20/28023 ,  B01J20/28033 ,  B01J20/28042 ,  B01J20/28078 ,  B01J20/28085 ,  B01J20/3035 ,  B01J20/305 ,  B01J20/321 ,  B01J20/3251 ,  B01J20/3274 ,  B01J20/328 ,  B01J20/3282 ,  B01J20/3289 ,  B01J2220/62 ,  B01J2220/82

Abstract: A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substrate has good convective and diffusive flow and capacity. The substrate may be crosslinked, have one or more capture chemistries attached to it and is useful as a chromatography media for the selective filtration of desired species including biomolecules such as proteins and DNA fragments.

Abstract translation: 能够吸附过滤具有多孔自支撑基底和一种或多种多孔吸附性涂层的多孔基材，其包含基材孔隙体积的约1至约80％。 所得到的底物具有良好的对流和扩散流量和容量。 底物可以是交联的，具有一个或多个捕获化学物质连接到其上，并且可用作用于选择性过滤所需物质（包括生物分子例如蛋白质和DNA片段）的色谱介质。