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    Device for delivering charged powder for deposition
    91.
    发明授权
    Device for delivering charged powder for deposition 失效

    公开(公告)号：US06630027B2

    公开(公告)日：2003-10-07

    申请号：US09903397

    申请日：2001-07-11

    Applicant: George R. Pawlo

    Inventor： George R. Pawlo

    IPC: B05C502

    CPC classification number: B05B5/08

    Abstract: Provided, among other things, is a re-circulating particle feed apparatus comprising: a circular conduit of dimensions suitable for circulating gas with suspended particles; a deposition station comprising an opening onto the conduit, into which opening an electrostatic chuck fits, with a deposition surface of the chuck available to the interior of the conduit; and a propulsion device for maintaining fluid and particle circulation through the conduit, wherein the propulsion device is adapted to maintain fluid and particle circulation at a rate that brings a deposition effective amount of particles within a range of electro-attractive influence at the deposition station.

    Coating medical devices
    92.
    发明申请
    Coating medical devices 有权
    涂层医疗器械

    公开(公告)号：US20030143315A1

    公开(公告)日：2003-07-31

    申请号：US10301473

    申请日：2002-11-21

    Inventor： David Y.H. Pui ,  Da-Ren Chen

    IPC: A61L002/00 ,  B05D001/04

    CPC classification number: B05B5/0255 ,  A61F2/86 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/00 ,  A61L2300/622 ,  A61L2420/02 ,  B05B1/14 ,  B05B5/025 ,  B05B5/03 ,  B05B5/0533 ,  B05B5/08 ,  B05B5/082 ,  B05B7/066 ,  B05B7/0884 ,  B05B13/0228 ,  B05D1/002 ,  B05D1/04 ,  B05D1/045

    Abstract: Methods and systems for coating at least a portion of a medical device (e.g., a stent structure) include providing a plurality of coating particles (e.g., monodisperse coating particles) in a defined volume. For example, the particles may be provided using one or more nozzle structures, wherein each nozzle structure includes at least one opening terminating at a dispensing end. The plurality of coating particles may be provided in the defined volume by dispensing a plurality of microdroplets having an electrical charge associated therewith from the dispensing ends of the one or more nozzle structures through use of a nonuniform electrical field between the dispensing ends and the medical device. Electrical charge is concentrated on the particle as the microdroplet evaporates. With a plurality of coating particles provided in the defined volume, such particles can be moved towards at least one surface of the medical device to form a coating thereon (e.g., using an electric field and/or a thermophoretic effect).

    Abstract translation: 用于涂覆医疗装置（例如，支架结构）的至少一部分的方法和系统包括在限定体积内提供多个涂层颗粒（例如，单分散涂层颗粒）。 例如，可以使用一个或多个喷嘴结构来提供颗粒，其中每个喷嘴结构包括终止于分配端的至少一个开口。 通过使用分配端和医疗装置之间的不均匀的电场，可以通过从一个或多个喷嘴结构的分配端分配具有与其相关联的电荷的多个微滴，来将多个涂层颗粒设置在限定的体积中 。 当微滴蒸发时，电荷集中在颗粒上。 利用设置在限定体积中的多个涂覆颗粒，这样的颗粒可以朝向医疗装置的至少一个表面移动以在其上形成涂层（例如，使用电场和/或热溶胶效应）。

    Method and apparatus for electrically controlling a flow of material
    93.
    发明授权
    Method and apparatus for electrically controlling a flow of material 有权
    用于电控制材料流动的方法和装置

    公开(公告)号：US06524659B1

    公开(公告)日：2003-02-25

    申请号：US09700471

    申请日：2000-11-15

    Applicant: Leo Hatjasalo ,  Jarkko Valtanen

    Inventor： Leo Hatjasalo ,  Jarkko Valtanen

    IPC: B05D132

    CPC classification number: B05D1/04 ,  B05B5/001 ,  B05B5/08 ,  B29C41/006 ,  B29C41/52 ,  B29L2031/4864

    Abstract: The invention relates to a method for electrically controlling a flow of material, wherein a single- or multi-component, essentially polymer-based material (1), such as plastics, elastomer or the like, is charged electrically (I) and sprayed (II) in an electrical field (E) to a three-dimensional mould (2)/target (3). The method of the invention makes use of the mould (2)/target (3) set at an electric potential and provided with two or more treatment blocks (Li) to be set at voltage levels different from each other, especially for coordinating the courses of sprayed material particles and the electrical field (E) affecting the same, in such a manner that each section/area of the mould/target surface forms a material layer of desirable thickness in the spraying cycle (II). The invention relates also to an apparatus operating in accordance with the method.

    Abstract translation: 本发明涉及一种用于电控制材料流动的方法，其中单组分或多组分基本上聚合物基材料（1），例如塑料，弹性体等被电（I）和喷涂（ II）在电场（E）到三维模具（2）/靶（3）。 本发明的方法利用设置在电位上的模具（2）/靶（3），并且设置有两个或更多个处理块（Li）设置在彼此不同的电压电平，特别是用于协调课程 的喷涂材料颗粒和影响其的电场（E），使得模具/靶表面的每个区域/面积在喷涂周期（II）中形成期望厚度的材料层。 本发明还涉及根据该方法操作的装置。

    High mass throughput particle generation using multiple nozzle spraying
    96.
    发明申请
    High mass throughput particle generation using multiple nozzle spraying 有权
    使用多喷嘴喷雾的高质量通量粒子产生

    公开(公告)号：US20020007869A1

    公开(公告)日：2002-01-24

    申请号：US09858865

    申请日：2001-05-16

    Inventor： David Y.H. Pui ,  Da-Ren Chen

    IPC: B67C003/00 ,  B65B043/42 ,  C12N013/00 ,  A61M011/00

    CPC classification number: B05B5/032 ,  A61F2/86 ,  B05B1/14 ,  B05B5/025 ,  B05B5/0255 ,  B05B5/08 ,  B05B5/087 ,  B05B7/0408 ,  B05B7/066 ,  B05B13/06

    Abstract: Spraying apparatus and methods that employ multiple nozzle structures for producing multiple sprays of particles, e.g., nanoparticles, for various applications, e.g., pharmaceuticals, are provided. For example, an electrospray dispensing device may include a plurality of nozzle structures, wherein each nozzle structure is separated from adjacent nozzle structures by an internozzle distance. Sprays of particles are established from the nozzle structures by creating a nonuniform electrical field between the nozzle structures and an electrode electrically isolated therefrom.

    Abstract translation: 提供了使用多个喷嘴结构来产生多种喷雾剂的喷涂设备和方法，例如纳米颗粒，用于各种应用，例如药物。 例如，电喷雾分配装置可以包括多个喷嘴结构，其中每个喷嘴结构通过内部喷嘴距离与相邻喷嘴结构分离。 通过在喷嘴结构和与其电隔离的电极之间产生不均匀的电场，从喷嘴结构建立颗粒喷雾。

    Method of depositing particles with an electrostatic chuck
    97.
    发明申请
    Method of depositing particles with an electrostatic chuck 失效
    用静电卡盘沉积颗粒的方法

    公开(公告)号：US20010018098A1

    公开(公告)日：2001-08-30

    申请号：US09740123

    申请日：2000-12-19

    Inventor： Hoi Cheong Steve Sun ,  Timothy Allen Pletcher

    IPC: B05D001/06 ,  B05B005/025

    CPC classification number: B05B5/087 ,  A61K9/2086 ,  A61K9/2893 ,  B01J2219/00468 ,  B05B5/08 ,  B05B5/082 ,  H02N13/00 ,  Y10T428/2991

    Abstract: The present invention is directed to electrostatic chucks, methods for their use, the electrostatic deposition of objects, such as particles in a dry powder, onto recipient substrates, and the recipient substrates themselves that have been subjected to electrostatic deposition. In one aspect, the present invention provides an electrostatic chuck for electrostatically attracting an object or objects wherein the object is used in chemical or pharmaceutical assaying or manufacturing. The objects can be pharmaceutical substrates, for example, such as a pharmaceutical tablet. Additional embodiments of the invention provide chucks and their use to electrostatically attract particles, such as a pharmaceutically active ingredient, to a substrate, such as a tablet. In one aspect, the electrostatic chuck comprises a floating electrode, and is used to selectively attract particles to a substrate above the floating electrode, thereby providing for charge imaging for the deposition of particles in a selected image. Additionally, the invention provides comprising a sensing electrode, optionally for use with an electrostatic chuck, for sensing the number of particles attracted to the objects on the chuck or other substrate, thereby providing for deposition of an accurate amount of particles. Furthermore, the present invention provides objects having selected areas in which particles are applied to the object via electrostatic means.

    Abstract translation: 本发明涉及静电卡盘，它们的使用方法，诸如干粉末中的物体的静电沉积到受体基底上，以及已经经过静电沉积的受体底物本身。 一方面，本发明提供一种用于静电吸引物体的静电吸盘，其中该物体用于化学或药物测定或制造。 物体可以是药物底物，例如药物片剂。 本发明的另外的实施方案提供了卡盘及其用于静电吸引诸如药物活性成分的颗粒到底物例如片剂。 一方面，静电卡盘包括浮动电极，并且用于选择性地将颗粒吸引到浮动电极上方的衬底上，从而为选定图像中的颗粒沉积提供电荷成像。 另外，本发明提供了包括感测电极，可选地与静电卡盘一起使用，用于感测吸附到卡盘或其它基底上的物体的颗粒的数量，从而提供精确量的颗粒的沉积。 此外，本发明提供了具有通过静电装置将颗粒施加到物体的选择区域的物体。

    Method and apparatus for measuring the transfer efficiency of a coating material
    99.
    发明授权
    Method and apparatus for measuring the transfer efficiency of a coating material 失效
    用于测量涂层材料的转印效率的方法和装置

    公开(公告)号：US6120832A

    公开(公告)日：2000-09-19

    申请号：US199499

    申请日：1998-11-25

    Applicant: Paul P. Walsh ,  Charles F. Williams

    Inventor： Paul P. Walsh ,  Charles F. Williams

    IPC: B05B5/08 ,  B05B7/14 ,  B05B12/12 ,  B05D1/04

    CPC classification number: B05B12/124 ,  B05B5/08 ,  B05B7/14

    Abstract: A method and apparatus for measuring the transfer efficiency during the electrostatic spraying of a coating material (e.g. powder coating) is provided. The transfer efficiency can be measured during the test cycle rather than measuring an average transfer efficiency for an electrostatic spray cycle. A cycle may include the initial time when the substrate is "uncoated or clean" and an end point of the test when electrical insulating effects caused by accumulated powder on the substrate lead to a reduction in the transfer efficiency. The method uses computer based calculation software and a computer. The computer is connected to load cells that measure weight changes of a target substrate and a vessel containing the coating material to be sprayed.

    Abstract translation: 提供了一种用于测量在涂料（例如粉末涂料）的静电喷涂期间的转印效率的方法和装置。 转印效率可以在测试周期内测量，而不是测量静电喷涂周期的平均转印效率。 循环可以包括当基底“未涂覆或清洁”的初始时间，并且当在基底上积聚的粉末引起的电绝缘作用导致转印效率降低时，测试的终点。 该方法使用基于计算机的计算软件和计算机。 计算机连接到测量目标基底和包含待喷涂的涂料的容器的重量变化的称重传感器。

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