公开(公告)号：US20070035732A1

公开(公告)日：2007-02-15

申请号：US11456610

申请日：2006-07-11

Applicant: Robert Marsche ,  Wolfgang Fuchs ,  Harald Gebetsroither

Inventor： Robert Marsche ,  Wolfgang Fuchs ,  Harald Gebetsroither

IPC: G01J1/10 ,  G01N21/25

CPC classification number: G01J3/12 ,  G01J3/02 ,  G01J3/027 ,  G01J3/0275 ,  G01J2003/1217 ,  G01N2021/317

Abstract: Microplate reader (21) with a computer for controlling the components of said microplate reader (21), comprising a light source (15) for emitting light for irradiating samples (22) or transmitting light through samples (22), and a filter slide (1) situated in the excitation or detection beam path. The microplate reader (21) in accordance with the invention is characterized in that said filter slide (1) comprises an electronic memory (4) for recording and/or retrieving filter-specific data, with said filter-specific data comprising the number and intensity of the light flashes impinging upon a certain filter (2) of said filter slide (1) and/or the intensity and duration of all exposures performed, and that said filter slide (1) comprises a contact point (5,7) jointly with the microplate reader (21) for transmitting such filter-specific data from the computer to the electronic memory (4) of the filter slide (1) and for retrieving such filter-specific data with the computer. According to the method in accordance with the invention for acquiring filter-specific data in a filter slide (1) of such a microplate reader (21), filter-specific data which comprise the number and intensity of the light flashes impinging upon a specific filter (2) of said filter slide (1) and/or the intensity and duration of all exposures performed are transmitted by the computer via a contact point common to said filter slide (1) and the microplate reader (21) to an electronic memory (4) of said filter slide (1) and/or are retrieved with the computer from said electronic memory (4).

Abstract translation: 一种用于控制所述微板读数器（21）的组件的计算机的微孔板读数器（21），包括用于发射用于照射样品（22）的光或者通过样品（22）透射光的光源（15） 1）位于激励或检测光束路径中。 根据本发明的酶标仪（21）的特征在于，所述过滤器滑块（1）包括用于记录和/或检索过滤器特定数据的电子存储器（4），所述过滤器特定数据包括数量和强度 撞击在所述过滤器滑块（1）的某个过滤器（2）上的闪光和/或所执行的所有曝光的强度和持续时间，并且所述过滤器滑块（1）包括与 所述微板读数器（21）用于将所述过滤器特定数据从所述计算机发送到所述过滤器滑板（1）的所述电子存储器（4）并且用所述计算机检索所述过滤器特定数据。 根据本发明的用于在这种酶标板读数器（21）的滤光片（1）中获得滤光器特定数据的方法，滤光器专用数据包括闪光的数量和强度，其冲击特定滤光片 （1）和/或所执行的所有曝光的强度和持续时间由计算机通过所述过滤板（1）和微板读数器（21）共同的接触点传送到电子存储器（ 4）和/或从所述电子存储器（4）用计算机检索。

公开(公告)号：US07162383B2

公开(公告)日：2007-01-09

申请号：US10833007

申请日：2004-04-28

Applicant: Isamu Takemura

Inventor： Isamu Takemura

IPC: G01J1/10

CPC classification number: G01B5/28 ,  G01B5/20

Abstract: In a calibration method for a surface texture measuring instrument which measures a surface of a workpiece and includes an arm that is supported to be swingable around a base point thereof and is provided with a contact point at an end for scanning the workpiece surface, the calibration method includes a measurement step for measuring a calibration gauge of which cross section contains a part of a substantially perfect circle, an assignment step for assigning the detection results, which are obtained in the measurement step, in an evaluation formula based on a circle equation in which the center coordinates of the calibration gauge are (xc, zc) and the radius is “r”, and a calibration step for calibrating each parameter based on the evaluation formula obtained in the assignment step.

Abstract translation: 在用于测量工件表面的表面纹理测量仪的校准方法中，包括支撑在其基点附近摆动的臂，并且在用于扫描工件表面的端部设置有接触点，校准 方法包括：测量步骤，用于测量横截面包含基本上完整圆的一部分的校准量规;分配步骤，用于将在测量步骤中获得的检测结果分配在基于圆形方程式的评估公式中 其中校准量规的中心坐标是（x，c，z，c），半径是“r”，以及校准步骤，用于基于评估来校准每个参数 在分配步骤中获得的公式。

公开(公告)号：US07161135B2

公开(公告)日：2007-01-09

申请号：US10884049

申请日：2004-07-02

Applicant: John D. Fergason

Inventor： John D. Fergason

IPC: G01J1/10 ,  G01J1/44 ,  A61F9/06 ,  F16P1/06

CPC classification number: A61F9/067 ,  B23K9/32

Abstract: A multi-stage control for an auto-darkening lens includes a first detector to detect initiation of welding and a second detector to detect continuation of welding after welding has been initiated. The first detector has relatively low sensitivity and fast response time; and the second detector has relatively high sensitivity that can be altered as may be necessary, relatively slow response time to allow opportunity to determine whether welding is continuing as inputs indicative of welding, and adaptive filtering to filter ambient effects and the like from such inputs to avoid false detection of welding. A method of enhancing operation of an auto-darkening lens control that has a detector and associated circuitry to detect initiation of welding substantially independently of time based filtering and to maintain detecting of welding using time based discrimination, comprising coupling control signals and power to an auto-darkening lens via a substantially unimpeded path from a detector to the auto-darkening lens.

Abstract translation: 用于自动变暗透镜的多级控制包括用于检测焊接开始的第一检测器和用于检测焊接之后的焊接继续的第二检测器。 第一个检测器灵敏度相对较低，响应时间快; 并且第二检测器具有相对较高的灵敏度，其可以根据需要进行改变，相对较慢的响应时间，以允许机会确定焊接是否持续作为指示焊接的输入，以及自适应滤波以从这些输入过滤环境效应等 避免焊接错误检测。 一种增强自动变暗透镜控制的操作的方法，其具有检测器和相关联的电路，以基本上独立于基于时间的滤波来检测焊接的启动，并且使用基于时间的判别来维持焊接检测，包括将控制信号和功率耦合到自动 通过从检测器到自动变暗透镜的基本上不受阻碍的路径来调光。

公开(公告)号：US20060139630A1

公开(公告)日：2006-06-29

申请号：US11040610

申请日：2005-01-19

Applicant: Jinsheng Yu ,  Jiang Lan ,  Xiaolin Yang ,  Xiaodong Wu

Inventor： Jinsheng Yu ,  Jiang Lan ,  Xiaolin Yang ,  Xiaodong Wu

IPC: G01J1/10

CPC classification number: G01J1/42 ,  G01J1/0271 ,  G01J1/04 ,  G01J1/0418 ,  G01J1/08 ,  G01N21/278 ,  G01N21/76

Abstract: A standard light source for single photon count apparatus, comprising: a housing; a light emitting diode; a light-shielding plate, disposed above said light emitting diode, for weakening the light intensity emitted by the light emitting diode; and a light-shielding filler for blocking the light emitted by the light emitting diode propagating downward, said light shielding filler, said light shielding plate and said LED are sealed in said housing integrally.

Abstract translation: 一种用于单光子计数装置的标准光源，包括：壳体; 一个发光二极管; 设置在所述发光二极管上方的遮光板，用于削弱由所述发光二极管发射的光强度; 以及用于阻挡由向下传播的发光二极管发射的光的遮光填料，所述遮光填料，所述遮光板和所述LED被一体地密封在所述壳体中。

公开(公告)号：US07061608B2

公开(公告)日：2006-06-13

申请号：US10768644

申请日：2004-01-30

Applicant: John Thomas Bradshaw ,  Richard H. Curtis

Inventor： John Thomas Bradshaw ,  Richard H. Curtis

IPC: G01J3/42 ,  G01J1/10

CPC classification number: G01N21/274 ,  G01N21/278 ,  G01N21/31 ,  G01N2021/054 ,  G01N2201/127 ,  G01N2201/1285 ,  G01N2201/1286

Abstract: An apparatus and related method for optical calibration of spectrophotometers is described. The apparatus is a calibration plate including one or more cuvettes filled with solutions of interest. The cuvettes are sealed to prevent evaporation. The cuvettes also possess a compressible component to allow for expansion of the solution and a bubble control apparatus to ensure that the compressible component does not intersect the beam path. A piece of neutral density glass is optionally included in the apparatus to track optical changes of the solutions over time.

Abstract translation: 描述了用于分光光度计的光学校准的装置和相关方法。 该装置是包括一个或多个充满感兴趣的溶液的比色杯的校准板。 试管被密封以防止蒸发。 试管还具有允许溶液膨胀的可压缩部件和气泡控制装置，以确保可压缩部件不与光束路径相交。 装置中可选地包括一片中性密度玻璃，以跟踪溶液随时间的光学变化。

公开(公告)号：US07054000B2

公开(公告)日：2006-05-30

申请号：US10633605

申请日：2003-08-04

Applicant: Arkady Nikitin ,  Albert Sicignano ,  Dmitriy Yeremin ,  Tim Goldburt

Inventor： Arkady Nikitin ,  Albert Sicignano ,  Dmitriy Yeremin ,  Tim Goldburt

IPC: G01J1/10

CPC classification number: G01B9/04 ,  G02B21/00

Abstract: A method of calibration of magnification of a microscope with the use of a diffraction grating has the steps of determining a mean period of a diffraction grating by irradiating the diffraction grating with an electromagnetic radiation having a known wavelength and analyzing a resulting diffraction pattern, determining a scatter of individual values of a period of the diffraction grating by multiple measurements of periods of the diffraction grating by a microscope in pixels in one area in a microscope field of view, and calculating a mean value of the period and the scatter based on the measurements, determining a sufficient number of measurements of the period for providing an accepted statistic error of a magnification of the microscope, performing measurements corresponding to the determined acceptable number of measurements, of individual values of the period in pixels in a plurality of portions of the diffraction grating, calculating a general mean value of the period in pixels based on the immediately preceding step, and finally calculating a parameter corresponding to the magnification of the microscope based on the determined mean value of the period of the diffraction grating in the microscope image and the calculating of the general mean value of the period in pixels.

Abstract translation: 使用衍射光栅校准显微镜的放大倍数的方法具有以下步骤：通过用具有已知波长的电磁辐射照射衍射光栅来确定衍射光栅的平均周期，并分析所得到的衍射图案，确定 通过显微镜在显微镜视场中的一个区域中的像素中的衍射光栅的周期的多次测量来分散衍射光栅的周期的各个值，并且基于测量值来计算周期的平均值和散射 ，确定用于提供显微镜的放大倍数的可接受的统计误差的足够数量的测量值，对所确定的可接受测量数量执行与衍射的多个部分中的像素周期的各个值的各个值的测量值 光栅，计算周期的一般平均值（以像素为单位）b 并且最终基于所确定的显微镜图像中的衍射光栅的周期的平均值和周期的平均值的计算（以像素为单位）来计算与显微镜的放大率对应的参数。

公开(公告)号：US07016032B2

公开(公告)日：2006-03-21

申请号：US10672114

申请日：2003-09-26

Applicant: Juergen Wulf ,  Andreas Fina ,  Michael Eberhard

Inventor： Juergen Wulf ,  Andreas Fina ,  Michael Eberhard

IPC: G01J1/10

CPC classification number: G01N21/278 ,  G01N21/6452

Abstract: The invention is directed to a device for calibrating an optical detection channel for a two-dimensional, spatially dependent measurement of fluorescent or luminescent radiation in multi-specimen carriers. The invention provides a system for calibrating an optical detection channel for a two-dimensional, spatially dependent measurement of fluorescent or luminescent radiation in multi-specimen carriers permitting a highly accurate calibration of the spatial sensitivity distribution of the sensor array in the detection channel. The invention provides a plate-shaped housing, a luminescent foil inside the housing which is arranged parallel to the window so as to cover its surface, a power source and control units which are provided in the housing for controlling the luminescent foil, so that the luminescent foil can be controlled for homogeneous emission of luminescent light through the window of the housing in different intensity levels.

Abstract translation: 本发明涉及用于校准用于多样本载体中的荧光或发光辐射的二维空间依赖性测量的光学检测通道的装置。 本发明提供了一种用于校准光学检测通道的系统，用于在多个样本载体中进行二维，空间依赖的荧光或发光辐射测量，从而允许在检测通道中高精度校准传感器阵列的空间灵敏度分布。 本发明提供了一种板状壳体，壳体内的发光箔，其平行于窗口布置以覆盖其表面，电源和控制单元，其设置在壳体中用于控制发光箔，使得 可以控制发光箔以通过不同强度水平的壳体的窗口均匀发射发光。

公开(公告)号：US20050275836A1

公开(公告)日：2005-12-15

申请号：US11152936

申请日：2005-06-15

Applicant: Felix Feldchtein ,  J. Breedlove ,  Stephanie Harrington

Inventor： Felix Feldchtein ,  J. Breedlove ,  Stephanie Harrington

IPC: G01J1/10 ,  G01N21/27 ,  G01N21/47

CPC classification number: G01N21/274 ,  G01N21/27 ,  G01N21/278 ,  G01N21/4795

Abstract: An optical measurement device calibration tool includes an optical probe suitable for calibrating various optical imaging devices, for example, low coherence reflectometers and optical coherence tomography devices. In a preferred embodiment the calibration tool comprises a container containing a calibration substance with stable optical scattering and absorption properties. The calibration substance includes a gel, paste or grease substance and is covered a protective seal, which is at least partially transparent providing optical contact between the optical probe and the calibration substance. The protective seal is covered with a viscous complementary material. Another protective seal made at least partially removable is placed above the viscous complementary material and may serve as a cover for the container. The calibration tool maintains the advantages of calibration tools using liquids and solid states as calibration substance and is more cost-effective and more convenient for calibrating optical measuring devices such as in medical applications.

Abstract translation: 光学测量装置校准工具包括适于校准各种光学成像装置的光学探针，例如低相干反射计和光学相干断层摄影装置。 在优选实施例中，校准工具包括容纳具有稳定的光散射和吸收特性的校准物质的容器。 校准物质包括凝胶，糊剂或油脂物质，并被覆盖保护性密封件，该保护性密封件至少部分透明，提供光学探针与校准物质之间的光学接触。 保护性密封件用粘性补充材料覆盖。 至少部分可移除的另一个保护性密封件放置在粘性互补材料上方，并可用作容器的盖子。 该校准工具保持了使用液体和固态作为校准物质的校准工具的优点，并且对于校准诸如医疗应用中的光学测量装置更为经济高效并且更方便。

公开(公告)号：US20050178954A1

公开(公告)日：2005-08-18

申请号：US11052091

申请日：2005-02-08

Applicant: Yohei Yukawa

Inventor： Yohei Yukawa

IPC: G01N21/17 ,  B60Q1/08 ,  B60Q1/14 ,  B60S1/08 ,  G01J1/02 ,  G01J1/10 ,  G01J1/42 ,  G01W1/14 ,  G05B11/00 ,  H01L27/00 ,  H01L31/101

CPC classification number: B60S1/0818 ,  B60Q1/1423 ,  B60Q2300/312 ,  B60Q2300/314 ,  B60S1/0833 ,  B60S1/087 ,  H01L31/101

Abstract: An optical sensor device includes a luminescence element for emitting ray toward a windshield of a vehicle, and a photoreception element for detecting ray projected thereon. A sensor case is provided for accommodating the photoreception element and the luminescence element, which is activated by a control unit according to a predetermined luminescence pattern. The control unit switches an output of the photoreception element as an output of a rain sensor or an illumination sensor, based on the predetermined luminescence pattern of the luminescence element. Accordingly, the rain sensor and the illumination sensor can share the same photoreception element, thus small-sizing the optical sensor device.

Abstract translation: 光学传感器装置包括用于向车辆的挡风玻璃发射射线的发光元件和用于检测投射在其上的射线的光接收元件。 提供一种用于容纳根据预定发光图案由控制单元激活的光接收元件和发光元件的传感器外壳。 控制单元基于发光元件的预定发光图案来切换作为雨传感器或照明传感器的输出的光接收元件的输出。 因此，雨传感器和照明传感器可以共享相同的光接收元件，从而使光学传感器设备的尺寸小。

公开(公告)号：US20050030530A1

公开(公告)日：2005-02-10

申请号：US10633605

申请日：2003-08-04

Applicant: Arkady Nikitin ,  Albert Sicignano ,  Dmitriy Yeremin ,  Tim Goldburt

Inventor： Arkady Nikitin ,  Albert Sicignano ,  Dmitriy Yeremin ,  Tim Goldburt

IPC: G01B9/04 ,  G01J1/10 ,  G02B21/00

CPC classification number: G01B9/04 ,  G02B21/00

Abstract: A method of calibration of magnification of a microscope with the use of a diffraction grating has the steps of determining a mean period of a diffraction grating by irradiating the diffraction grating with an electromagnetic radiation having a known wavelength and analyzing a resulting diffraction pattern, determining a scatter of individual values of a period of the diffraction grating by multiple measurements of periods of the diffraction grating by a microscope in pixels in one area in a microscope field of view, and calculating a mean value of the period and the scatter based on the measurements, determining a sufficient number of measurements of the period for providing an accepted statistic error of a magnification of the microscope, performing measurements corresponding to the determined acceptable number of measurements, of individual values of the period in pixels in a plurality of portions of the diffraction grating, calculating a general mean value of the period in pixels based on the immediately preceding step, and finally calculating a parameter corresponding to the magnification of the microscope based on the determined mean value of the period of the diffraction grating in the microscope image and the calculating of the general mean value of the period in pixels.

Abstract translation: 使用衍射光栅校准显微镜的放大倍数的方法具有以下步骤：通过用具有已知波长的电磁辐射照射衍射光栅来确定衍射光栅的平均周期，并分析所得到的衍射图案，确定 通过显微镜在显微镜视场中的一个区域中的像素中的衍射光栅的周期的多次测量来分散衍射光栅的周期的各个值，并且基于测量值来计算周期的平均值和散射 ，确定用于提供显微镜的放大倍数的可接受的统计误差的足够数量的测量值，对所确定的可接受测量数量执行与衍射的多个部分中的像素周期的各个值的各个值的测量值 光栅，计算周期的一般平均值（以像素为单位）b 并且最终基于所确定的显微镜图像中的衍射光栅的周期的平均值和周期的平均值的计算（以像素为单位）来计算与显微镜的放大率对应的参数。