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101.
公开(公告)号:US11445784B2
公开(公告)日:2022-09-20
申请号:US16592883
申请日:2019-10-04
Applicant: Worcester Polytechnic Institute
Inventor: Christopher A. Brown , James J. Muller , Winton Parker , Allysa Grant , Tristin J. Carlton , Nicholas Workman , Michael Doyle , Jessica Shelsky , Jessica K. Y. Cheu , Lorenzo Dube , Pedro D. Oporto , Olivia G. Steen , Andrew R. Vickery
Abstract: A force absorbing device for a footwear appliance includes a shoe upper and a shoe sole having a planar sole surface, such that forces between the shoe upper and planar sole surface in ground contact are absorbed by force mitigation structures disposed in the shoe sole. A footwear article includes a split-sole system that redefines a shoe sole as coplanar surfaces having a force mitigating interface for receiving sudden forces and effectively mitigating these forces by storing kinetic energy and releasing it over time. An elastic field in the force mitigation structure is defined by a resilient material adapted to deform in response to the received force. Frictional engagement between the upper and lower sole may also be augmented by surface characteristics such as dimples, voids and lubricants, in addition to interference engagement with an elastic field.
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公开(公告)号:US20220160207A1
公开(公告)日:2022-05-26
申请号:US17532240
申请日:2021-11-22
Inventor: CHRISTOPHER J. NYCZ , ELIZABETH M. ALBRECHT , MEGAN CHROBAK , KIANOOSH GHAZI , GREGORY SCOTT FISCHER , BRYAN ALLEN CLARK
Abstract: An endoscopic system may include an endoscope including a handle and an elongate shaft extending distally therefrom. The handle may include a non-motorized and non-ratcheting actuation mechanism configured to articulate a distal tip portion of the elongate shaft. The distal tip portion may be articulatable in response to a manually applied force exerted upon the actuation mechanism. Removal of the manually applied force may lock the distal tip portion in its then-current configuration. The non-motorized and non-ratcheting actuation mechanism may include a clutch mechanism actuatable in response to an electrical signal generated in response to sensing a user-applied force to the actuating mechanism by a strain gauge.
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103.
公开(公告)号:US20220054710A1
公开(公告)日:2022-02-24
申请号:US17465102
申请日:2021-09-02
Applicant: Worcester Polytechnic Institute
Inventor: Jeannine Coburn , Glenn Gaudette , Nhi Phan
Abstract: Provided herein are enzymatically decellularized cells, and methods of producing said cells, that can be used in a scaffold. The scaffolds featured herein are biocompatible and can comprise decellularized cells that have been modified to express a bioactive agent or molecule.
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公开(公告)号:US11249100B2
公开(公告)日:2022-02-15
申请号:US16240720
申请日:2019-01-05
Applicant: Worcester Polytechnic Institute
Inventor: Dirk Albrecht , Ross Lagoy
Abstract: Systems and methods for delivering fluid to a microfluidic device is provided. The system includes a multi-well plate having a plurality of wells and an inlet tube having a first end being in communication with the one or more wells of the multi-well plate and a second end being in communication with a microfluidic device. The first end of the inlet tube is moveable between the plurality of wells of the multi-well plate to deliver fluid to the microfluidic device from the plurality of wells of the multi-well plate.
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公开(公告)号:US11248995B2
公开(公告)日:2022-02-15
申请号:US16129581
申请日:2018-09-12
Applicant: Worcester Polytechnic Institute
Inventor: Dirk Albrecht , Ross Lagoy , Kyra Burnett
IPC: G01N1/30 , G01N1/44 , G01N1/36 , G01N21/64 , G01N33/483
Abstract: Devices and methods for capturing and imaging a specimen, such as a living organism, are disclosed. In some embodiments, a method for imaging a living organism in vivo includes placing at least one specimen into a hydrogel polymer on a substrate, and curing the hydrogel to embed the at least one specimen within the cured hydrogel such that the at least one specimen is kept alive and the movement of the at least one specimen within the cured hydrogel is restricted. The at least one embedded specimen can be imaged.
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公开(公告)号:US20210372001A1
公开(公告)日:2021-12-02
申请号:US17330922
申请日:2021-05-26
Applicant: Worcester Polytechnic Institute
Inventor: Yan Wang , Xiaotu MA , Eric Gratz , Jinzhao Fu , Panawan Vanaphuti
Abstract: A recycling and synthesis of charge material for secondary batteries generates single-crystal charge materials for producing batteries with greater charge cycle longevity. Charge material particles undergo a heating for fusing or enhancing grain boundaries between polycrystalline particles. The resulting, more well-defined grain boundaries are easily etched by a relatively weak mineral acid solution. The acid solution removes material at the grain boundaries to separate secondary particles into primary particles along the grain boundaries. The resulting single crystal (monocrystalline) charge material particles are washed and filtered, and typically re-sintered to accommodate any needed lithium (lithium carbonate), and result in a charge material with larger surface area, higher lithium diffusivity and lower cation ordering.
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公开(公告)号:US20210171931A1
公开(公告)日:2021-06-10
申请号:US16931967
申请日:2020-07-17
Applicant: Worcester Polytechnic Institute
Inventor: Amy Peterson , Marsha Rolle , Ivan Ding
Abstract: Device, and methods of using or making the device, for engineering cells in vitro are disclosed. In some aspects, a cell culture device comprises at least one glass or polymer surface configured for incubating cells in a culture medium; a charged molecule electrostatically bound to the surface; and a polyelectrolyte multilayer (PEM) electrostatically bound to the charged molecule, the PEM comprising one or more bi-layers of oppositely charged polyelectrolytes, and the PEM having a sufficient thickness to permit release of the charged molecule into the culture medium in a controlled released manner.
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公开(公告)号:US20210127783A1
公开(公告)日:2021-05-06
申请号:US17094978
申请日:2020-11-11
Applicant: Worcester Polytechnic Institute
Inventor: Christopher A. Brown , Tristin J. Carlton , Eric Motler , Douglas Rives , Austin Lindner , Joshua M. Herlands , Jessica K.Y. Chen , Lorenzo M. Dube , James J. Muller , Pedro D. Oporto , Olivia G. Steen , Andrew R. Vickery
Abstract: A protective headgear device, or helmet, protects against head injuries such as concussions and CTE by imposing a network of constant force members (CFMs) between an outer impact shell and an inner fitted capsule engaging the skull/head surface. CFMs exhibit a force absorbing behavior that differs from conventional linear spring behavior that impose a counterforce proportional to the displaced distance. CFMs occupy a compact void between the outer impact shell and the inner fitted capsule by component miniaturization and tethers that redirect forces within the void. An absence of conventional foam and straps increases accommodation for the CFMs and connection tethers/attachments. The CFMs exhibit a substantially constant force that avoids a sharp impactful response associated with head injuries.
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公开(公告)号:US10953432B2
公开(公告)日:2021-03-23
申请号:US16000154
申请日:2018-06-05
Applicant: Worcester Polytechnic Institute
Inventor: Pratap Rao
Abstract: A superhydrophobic surface is formed by growing a plurality of etchable, sacrificial structures, and depositing a discontinuous hydrophobic material onto the sacrificial structures. The discontinuity facilitates etching of the sacrificial structures to remove the grown structures while leaving the deposited material intact to result in surface features for achieving superior hydrophobic properties.
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公开(公告)号:US10952888B2
公开(公告)日:2021-03-23
申请号:US16014386
申请日:2018-06-21
Applicant: Worcester Polytechnic Institute
Inventor: Marko Popovic , Saivimal Sridar , Corey Majeika , Nicholas Deisadze , Erika Giancarlo
Abstract: Variable stiffness devices and methods of their use are provided. In some embodiments, a variable stiffness device comprises an inner member defining a compartment for receiving an actuating fluid; an outer member disposed around the inner member; and a granular medium disposed between the inner member and the outer member; wherein the inner member is being moveable in a radial direction from a relaxed state to an expanded state by introducing the actuating fluid into the compartment of the inner member to compress the granular medium against the outer member to increase the stiffness of the device.
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