THERMOCHROMIC SENSING FOR NANOCALORIMETRY
    117.
    发明申请

    公开(公告)号:US20170191881A1

    公开(公告)日:2017-07-06

    申请号:US14984754

    申请日:2015-12-30

    Abstract: A nanocalorimeter device includes a substrate having test cells, each test cell comprising a sample location. Each sample location includes a reaction surface suitable for an enthalpic reaction of constituents of liquid droplets, droplet movement and configured to merge the droplets, and a layer of thermochromic material thermally coupled to the reaction surface. The thermochromic material is configured to exhibit a spectral shift in light emanating from the thermochromic material in response to a change in temperature of the merged droplets.

    Monitor for particle injector
    119.
    发明授权
    Monitor for particle injector 有权
    监测颗粒注射器

    公开(公告)号:US09400174B2

    公开(公告)日:2016-07-26

    申请号:US14246912

    申请日:2014-04-07

    Abstract: Approaches for determining the delivery success of a particle, such as a drug particle, are disclosed. A system for monitoring delivery of particles to biological tissue includes a volume, an optical component, a detector, and an analyzer. The volume comprises a space through which a particle can pass in a desired direction. The optical component is configured to provide a measurement light. The detector is positioned to detect light emanating from the particle in response to the measurement light. The detected light is modulated as the particle moves along a detection axis. The detector is configured to generate a time-varying signal in response to the detected light. The analyzer is configured to receive the time-varying signal and determine a delivery success of the particle into a biological tissue based upon characteristics of the time-varying signal.

    Abstract translation: 公开了确定颗粒如药物颗粒的递送成功的方法。 用于监测颗粒递送到生物组织的系统包括体积,光学部件,检测器和分析器。 该体积包括颗粒可以通过其沿所需方向通过的空间。 光学部件被配置成提供测量光。 检测器被定位成响应于测量光来检测从颗粒发出的光。 随着粒子沿着检测轴移动,被检测的光被调制。 检测器被配置为响应于检测到的光而产生时变信号。 分析器被配置为接收时变信号,并且基于时变信号的特性来确定颗粒进入生物组织的递送成功。

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