公开(公告)号：US3897154A

公开(公告)日：1975-07-29

申请号：US41623373

申请日：1973-11-15

Applicant: HAWES ROLAND C

Inventor： HAWES ROLAND C

IPC: G01J3/453 ,  G01N21/27 ,  G01N21/85 ,  G01N30/74 ,  G01N21/34 ,  G01J3/42

CPC classification number: G01J3/453 ,  G01N21/274 ,  G01N21/85 ,  G01N30/74

Abstract: Apparatus and process provide qualitative and quantitative analysis of sample constituent(s) in a fluid, relatively free from qualitative ambiguities and quantitative zero displacements due to slowly changing contamination in the measurement stream. Slowly changing zero displacement in the stream is cancelled out by the taking of continuous measurements at two points along the stream and continuously manipulating the two measurements as by subtraction.

Abstract translation: 设备和过程提供了流体中样品组分的定性和定量分析，相对没有定性歧义和定量的零位移，由于测量流中的污染物的缓慢变化。 通过在沿着流的两个点处进行连续测量来消除流中缓慢变化的零位移，并通过减法连续地操纵两个测量。

公开(公告)号：US20240180428A1

公开(公告)日：2024-06-06

申请号：US18438144

申请日：2024-02-09

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61C1/00 ,  A61C19/04 ,  G01J3/02 ,  G01J3/10 ,  G01J3/12 ,  G01J3/14 ,  G01J3/18 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/95 ,  G01N33/02 ,  G01N33/15 ,  G01N33/44 ,  G01N33/49 ,  G16H40/67 ,  G16Z99/00 ,  H01S3/00 ,  H01S3/067 ,  H01S3/30

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61C19/04 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01N21/35 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G16H40/67 ,  G16Z99/00 ,  A61B5/0024 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  A61C1/0046 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J3/1838 ,  G01J2003/2826 ,  G01M3/38 ,  G01N2021/3513 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N21/85 ,  G01N21/9508 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302 ,  Y02A90/10

Abstract: An optical system comprises a wearable device for measuring one or more physiological parameters. The physiological parameters may change in response to stretching of the hand or movement of fingers or thumb of the user, or the parameters may be related to blood constituents or blood flow. The wearable device comprises a light source with a plurality of semiconductor diodes and a detection system that measures reflected light from tissue comprising skin. The semiconductor diodes may be light emitting diodes or laser diodes. The signal to noise ratio for the output signal may be improved by synchronizing the detection system to the light source, increasing light intensity of at least one of the plurality of semiconductor diodes from an initial light intensity, and using change detection that compares light on versus light off for the detection system output. The wearable device is also configured to identify an object.

公开(公告)号：US11933732B2

公开(公告)日：2024-03-19

申请号：US17471139

申请日：2021-09-09

Applicant: UNM Rainforest Innovations

Inventor： Mani Hossein-Zadeh

IPC: G01N1/00 ,  G01J3/02 ,  G01J3/42 ,  G01J3/453 ,  G01N21/77 ,  G01N33/543 ,  G02B6/122 ,  G02B6/125

CPC classification number: G01N21/7703 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/42 ,  G01J3/453 ,  G01N33/54373 ,  G02B6/1223 ,  G02B6/1225 ,  G02B6/125 ,  G01N2201/0638

Abstract: The present invention provides a sensor having, one or more optical slab waveguides having one or more target regions. The target regions may interact with gas molecules or trap, entrain or capture one or more targets of interest. The optical slab waveguides are adapted to receive one or more input optical beams from one or more light sources to create a plurality of propagating optical waves in optical slab waveguide. The propagating optical waves interact with said one or more target regions to create an optical output wavefront that may be in the form of a diffraction pattern. The target regions may be functionalized with an antibody, polymer, cell, tissue, or biological material.

公开(公告)号：US20230277065A1

公开(公告)日：2023-09-07

申请号：US18118013

申请日：2023-03-06

Applicant: Omni Medsci, Inc.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  G01J3/02 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/145 ,  G01N33/15 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  A61B5/1455 ,  G16Z99/00 ,  A61C19/04 ,  G01N21/3504

CPC classification number: A61B5/0088 ,  A61B5/0075 ,  G01J3/108 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  A61B5/7257 ,  G01J3/0218 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4547 ,  G01N33/15 ,  G01N33/49 ,  G01J3/2823 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/442 ,  G01N21/88 ,  A61B5/6801 ,  A61B5/7405 ,  A61B5/742 ,  G01N33/025 ,  A61B5/1455 ,  G16Z99/00 ,  A61B5/7203 ,  A61C19/04 ,  G01J3/02 ,  G01N21/3504 ,  G01N2201/129 ,  H01S3/302

Abstract: A measurement system comprising one or more semiconductor diodes configured to penetrate tissue comprising skin. The detection system comprising a camera, which may also include a direct or indirect time-of-flight sensor. The detection system synchronized to the pulsing of the semiconductor diodes, and the camera further coupled to a processor. The detection system non-invasively measuring blood within the skin, measuring hemoglobin absorption between 700 to 1300 nm, and the processor deriving physiological parameters and comparing properties between different spatial locations and variation over time. The semiconductor diodes may comprise vertical cavity surface emitting lasers, and the detection system may comprise single photon avalanche photodiodes. The measurement system may be used to observe eye parameters and differential blood flow. The system may be used with photo-bio-modulation therapy, or it may be used in advanced driver monitoring systems for multiple functions including head pose, eye tracking, facial authentication, and smart restraint control systems.

公开(公告)号：US20230172455A1

公开(公告)日：2023-06-08

申请号：US18103408

申请日：2023-01-30

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  G01J3/02 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/145 ,  G01N33/15 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  A61B5/1455 ,  G16Z99/00 ,  A61C19/04 ,  G01N21/3504

CPC classification number: A61B5/0088 ,  A61B5/0075 ,  G01J3/108 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  A61B5/7257 ,  G01J3/0218 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4547 ,  G01N33/15 ,  G01N33/49 ,  G01J3/2823 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/442 ,  G01N21/88 ,  A61B5/6801 ,  A61B5/7405 ,  A61B5/742 ,  G01N33/025 ,  A61B5/1455 ,  G16Z99/00 ,  A61B5/7203 ,  A61C19/04 ,  G01J3/02 ,  G01N21/3504 ,  G01N2201/129 ,  H01S3/302

Abstract: An optical system operating in the near or short-wave infrared wavelength range identifies an object based on water absorption. The system comprises a light source with modulated light emitting diodes operating at wavelengths near 1090 and 1440 nanometers, corresponding to lower and higher water absorption. The system further comprises one or more wavelength selective filters and a housing that is further coupled to an electrical circuit and a processor. The detection system comprises photodetectors that are synchronized to the light source, and the detection system receives at least a portion of light reflected from the object. The system is configured to identify the object by comparing the reflected light at the first and second wavelength to generate an output value, and then comparing the output value to a threshold. The optical system may be further coupled to a wearable device or a remote sensing system with a time-of-flight sensor.

公开(公告)号：US20190183346A1

公开(公告)日：2019-06-20

申请号：US16284514

申请日：2019-02-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G16H40/67 ,  G01N33/15 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01J3/02 ,  A61C19/04 ,  G01J3/14 ,  G01N33/49 ,  G01N33/44

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  A61C1/0046 ,  A61C19/04 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A smart phone or tablet includes laser diodes, at least some of which may be pulsed and generate near-infrared light and include Bragg reflectors to direct light to tissue/skin. An array of laser diodes generates near-infrared light and has an assembly in front of the array that forms the light into a plurality of spots on the tissue/skin. A receiver includes detectors that receive light reflected from the tissue/skin. An infrared camera receives light reflected from the tissue/skin and generates data based on the received light. The smart phone or tablet is configured to generate a two-dimensional or three-dimensional image using at least part of the data from the infrared camera.

公开(公告)号：US20180372652A1

公开(公告)日：2018-12-27

申请号：US15568958

申请日：2017-08-23

Applicant: KLA-Tencor Corporation

Inventor： Vincent Immer ,  Tal Marciano ,  Etay Lavert

IPC: G01N21/95 ,  G02B21/00 ,  G02B21/06 ,  G02B21/18 ,  H01L21/67 ,  H01L21/66 ,  G02B21/36 ,  G01J3/453 ,  G01N21/956

CPC classification number: G01N21/9501 ,  G01J3/453 ,  G01N21/31 ,  G01N21/55 ,  G01N21/956 ,  G02B21/0016 ,  G02B21/0056 ,  G02B21/06 ,  G02B21/082 ,  G02B21/18 ,  G02B21/365 ,  G03F7/70633 ,  H01L21/67259 ,  H01L22/12

Abstract: A device and method for expediting spectral measurement in metrological activities during semiconductor device fabrication through interferometric spectroscopy of white light illumination during calibration, overlay, and recipe creation.

公开(公告)号：US10082425B2

公开(公告)日：2018-09-25

申请号：US15282305

申请日：2016-09-30

Applicant: UNITY SEMICONDUCTOR

Inventor： Philippe Gastaldo

IPC: G01J3/02 ,  G01J3/453 ,  G01J3/18

CPC classification number: G01J3/0208 ,  G01B11/022 ,  G01B11/0608 ,  G01B11/22 ,  G01B11/245 ,  G01B2210/50 ,  G01B2210/56 ,  G01J3/0218 ,  G01J3/18 ,  G01J3/453 ,  G01N21/8806 ,  G01N21/8851 ,  G01N21/9501 ,  G01N21/956 ,  G01N2201/063 ,  G01N2201/0833 ,  G01N2201/105 ,  G02B21/0064 ,  H01L22/12

Abstract: A confocal chromatic device is provided, including at least one chromatic lens with an extended axial chromatism; at least one broadband light source; at least one optical detector; and at least one measurement channel with a planar Y-junction made with a planar waveguide optics technology, and arranged for transferring light from the at least one light source towards the at least one chromatic lens and for transferring light reflected back through the at least one chromatic lens towards the at least one optical detector.

公开(公告)号：US09995722B2

公开(公告)日：2018-06-12

申请号：US15855201

申请日：2017-12-27

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  G01N21/3563 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/44 ,  G01N33/49 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18 ,  G01M3/38

CPC classification number: G01N33/15 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/0088 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3513 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  H01S3/302

Abstract: A measurement system includes a light source having semiconductor sources configured to generate an input optical beam, a multiplexer configured form an intermediate optical beam from the input optical beam, fibers including a fused silica fiber configured to receive the intermediate optical beam and to form an output optical beam. The output optical beam comprises wavelengths between 700 and 2500 nanometers with a bandwidth of at least 10 nanometers. A measurement apparatus is configured to deliver the output beam to a sample to generate a spectroscopy output beam. A receiver is configured to receive and process the spectroscopy output beam to generate an output signal, wherein the receiver processing includes chemometrics or multivariate analysis methods to permit identification of materials within the sample, the light source and the receiver are remote from the sample, and the sample includes plastics or food industry goods.

公开(公告)号：US20180140198A1

公开(公告)日：2018-05-24

申请号：US15860065

申请日：2018-01-02

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/10 ,  G01J3/28 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01N21/88 ,  G01M3/38 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device includes a measurement device having light emitting diodes (LEDs) measuring a physiological parameter. The measurement device modulates the LEDs to generate an optical beam having a near-infrared wavelength between 700-2500 nanometers. Lenses receive and deliver the optical beam to tissue, which reflects the optical beam to a receiver having spatially separated detectors coupled to analog-to-digital converters configured to generate receiver outputs. The receiver captures light while the LEDs are off, and reflected light from the tissue while the LEDs are on, to generate first and second signals, respectively. Signal-to-noise ratio is improved by differencing the first and second signals and by differencing the receiver outputs. The measurement device further improves signal-to-noise ratio of the reflected optical beam by increasing light intensity of the LEDs relative to an initial light intensity. The measurement device generates an output signal representing a non-invasive measurement on blood contained within the tissue.