公开(公告)号：US11422033B2

公开(公告)日：2022-08-23

申请号：US17135675

申请日：2020-12-28

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US20220236247A1

公开(公告)日：2022-07-28

申请号：US17615572

申请日：2019-05-31

Applicant: DTE EHF.

Inventor： Sveinn Hinrik GUDMUNDSSON ,  Jon MATTHIASSON ,  Kristjan LEOSSON

IPC: G01N33/205 ,  G01N21/71 ,  G01J3/443

Abstract: A non-contact, non-immersive method and apparatus are provided for accurately measuring quantitatively one or more elements in liquid metal or alloy samples using laser-induced breakdown spectroscopy (LIBS). The method is particularly useful for process and/or quality control within the metallurgy industry for accurately and very quickly measuring minor component or impurity elements in liquid metal in the production process, without touching the liquid metal and without the need for cooling and solidifying samples for analysis. In the method and apparatus a pre-determined distance is dynamically maintained between emission receiving optics and the surface of a liquid sample being analysed and the instrument does not come in contact with the liquid metal surface. Liquid samples are heated and/or maintained at a desired temperature. For many elements, values for limit-of-detection, measurement repeatability and accuracy about or below 1 ppm are achieved using this method.

公开(公告)号：US20220205840A1

公开(公告)日：2022-06-30

申请号：US16429423

申请日：2019-06-03

Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Romain GAUME ,  Matthew JULIAN ,  Matthieu BAUDELET

IPC: G01J3/02 ,  G01N21/71 ,  G01N21/65 ,  G01J3/443

Abstract: A method for fabricating an optical source for calibrating an optical system is provided. The method includes determining a form factor for an optical source based on a point of detection of an optical system corresponding to a region where an optical signal of the optical system interacts with a sample. The method also includes providing an envelope in a size and shape to fit the form factor. The method also includes providing a plurality of electrodes connected to the envelope for connection to a power source and filling the envelope with a gas. The optical source formed from the above method is also provided.

公开(公告)号：US20220159912A1

公开(公告)日：2022-05-26

申请号：US17669744

申请日：2022-02-11

Applicant: Sensor Electronic Technology, Inc.

Inventor： Michael Shur ,  Alexander Dobrinsky ,  Maxim S. Shatalov ,  Arthur Peter Barber, III

IPC: A01G7/04 ,  G01N21/55 ,  G01J3/10 ,  G01J3/42 ,  G01J3/44 ,  G01J3/443 ,  A01G22/00 ,  A01G9/20 ,  G05B15/02

Abstract: An approach for controlling light exposure of a light sensitive object is described. Aspects of this approach involve using a first set of radiation sources to irradiate the object with visible radiation and infrared radiation. A second set of radiation sources spot irradiate the object in a set of locations with a target ultraviolet radiation having a range of wavelengths. Radiation sensors detect radiation reflected from the object and environment condition sensors detect conditions of the environment in which the object is located during irradiation. A controller controls irradiation of the light sensitive object by the first and second set of radiation sources according to predetermined optimal irradiation settings specified for various environmental conditions. In addition, the controller adjusts irradiation settings of the first and second set of radiation sources as a function of measurements obtained by the various sensors.

公开(公告)号：US11326949B2

公开(公告)日：2022-05-10

申请号：US17084334

申请日：2020-10-29

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic device may include a laser projection module projecting a pulsed laser to a specimen, a light receiving module receiving a light generated by a plasma ablation induced at the specimen by the pulsed laser, a spectral member receiving and dividing the light generated by the plasma ablation; a sensor array including a plurality of sensors arranged to receive the divided light for each wavelength, and a controller obtaining spectrum data of the light generated by the plasma ablation from a specific exposure period, and determining whether or not the specimen is diseased based on the spectrum data of the light generated by the plasma ablation.

公开(公告)号：US11313720B2

公开(公告)日：2022-04-26

申请号：US15003891

申请日：2016-01-22

Applicant: Rigaku Raman Technologies, Inc.

Inventor： Eric Roy ,  Jason Booth ,  Claude Robotham ,  Federico Izzia

IPC: G01J3/02 ,  G01J3/28 ,  G01J3/44 ,  G01J3/443

Abstract: This invention relates to a system and method to improve the signal to noise ratio (SNR) of optical spectrometers that are limited by nonrandom or fixed pattern noise. A signal from a sample is collected using a short test exposure, a total observation time to maximize SNR is calculated, and the total observation time is achieved by averaging multiple exposures whose time is selected based on the time dependent noise structure of the detector. Moreover, with a priori knowledge of the time dependent noise structure of the spectrometer, this method is easily automatable and can maximize SNR for a spectrum of an unknown compound without any user input.

公开(公告)号：US11275029B2

公开(公告)日：2022-03-15

申请号：US16706197

申请日：2019-12-06

Applicant: Elemental Scientific Lasers, LLC

Inventor： Robert W. Hutchinson ,  David N. Douglas

IPC: G01N21/71 ,  B23K26/40 ,  G01J3/443

Abstract: A laser-ablation-based analytical system can include a sample chamber input, a make-up gas input, a vacuum pump, and an output flow. The sample chamber input can be configured to deliver a sample chamber gas flow comprised of combination of a laser-ablated sample and a sample-carrier gas from a sample chamber. The make-up gas input can be configured to provide an amount of make-up gas to supplement the combination of the laser-ablated sample and the sample-carrier gas. The vacuum pump can be fluidly connected to the sample chamber input and the make-up gas input, the vacuum pump configured to create a negative pressure in a sample transport gas downstream of the vacuum pump, the sample transport gas including the make-up gas, the laser-ablated sample, and the sample-carrier gas. The output flow can be configured to deliver the sample transport gas from the vacuum pump to a detection device.

公开(公告)号：US11274968B2

公开(公告)日：2022-03-15

申请号：US17048081

申请日：2019-05-02

Applicant: Elementar Analysensysteme GmbH

Inventor： Hans Dominick ,  Michael Molderings

IPC: G01J3/443 ,  G01J3/02 ,  G01N21/67 ,  G01J3/10

Abstract: The invention relates to an optical emission spectrometer with a spark chamber (10) which comprises a spark stand opening (14) and an oblong electrode (11) being arranged inside thereof for generating a spark and a beam of light originating therefrom. Furthermore, a coupling unit (20) is provided which comprises at least one window being arranged on a window holder and a channel. The spark chamber (10) and the coupling unit (20) are arranged with respect to each other such that the beam of light falls through the window (30) into the channel (21). In addition, the spark chamber (10) and the coupling unit (20) comprise means for purging with an inert gas.
The spark chamber (10) is directly connected with a window holder (31) and via the window holder (31) with the coupling unit (20), wherein between spark chamber (10) and window holder (31) a sealing element (33) is provided. The coupling unit (20) comprises at least one elastic means which is arranged such that it presses the window holder (31) against the spark chamber (10).

公开(公告)号：US11248961B2

公开(公告)日：2022-02-15

申请号：US14205745

申请日：2014-03-12

Applicant: MAT International Holdings, LLC

Inventor： Catherine E. McManus ,  James W. Dowe, III ,  Tristan M. Likes ,  James W. Dowe, IV ,  Paul McManus ,  Nelson Winkless, III ,  Ashley Shelton ,  Karly Baughn ,  Robert Baughn ,  Regan Orr

IPC: G01J3/443 ,  G01N21/71 ,  G01J3/28

Abstract: The disclosure features methods for analyzing a sample, the methods including exposing the sample to plurality of pulses of electromagnetic radiation to convert a portion of the sample into a plasma, recording a spectrum of electromagnetic radiation emitted in response to each of the plurality of pulses to define a sequence of spectra for the sample, and using an electronic processor to determine information about the sample based on the spectra, where exposing the sample to the plurality of pulses of electromagnetic radiation includes directing the pulses to be incident on different spatial regions of the sample, and where a temporal delay between exposing the sample to each successive radiation pulse is constant.

公开(公告)号：US20210310956A1

公开(公告)日：2021-10-07

申请号：US17223941

申请日：2021-04-06

Applicant: Servomex Group Limited

Inventor： Bahram Alizadeh ,  Martin Lopez

IPC: G01N21/67 ,  G01N21/68 ,  G01J3/443

Abstract: Provided are methods, apparatuses and systems for enhanced determination of the gas composition of a sample gas using glow discharge optical emission spectroscopy (GD-OES) for gas analysis. A first method comprises: generating one or more oscillating electromagnetic fields within a plasma cell to excite particles within the cell, to produce a glow discharge plasma in the plasma cell, and controlling the operating conditions for the plasma cell while flowing a gas mixture through the plasma cell to maintain glow discharge optical emissions from the plasma within a desired operating range; and monitoring one or more glow discharge optical emissions from the plasma in the plasma cell; wherein said monitoring of the optical emissions comprises measuring the optical emissions, or measuring a signal that correlates with the optical emissions, at twice the plasma excitation frequency; and processing the signal during each excitation cycle of the electromagnetic excitation, to determine the concentration of a gas within a gas mixture flowing through the plasma cell.