-
公开(公告)号：US20230390189A1
公开(公告)日：2023-12-07
申请号：US18033689
申请日：2021-10-26
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Charles D. BLIZZARD , Arthur DRISCOLL , Rami EL-HAYEK , Michael GOLDSTEIN , Joseph IACONA , Peter JARRETT , Timothy S. JARRETT , Erica KAHN , Zachary LATTRELL
IPC: A61K9/00 , A61K45/06 , A61P27/02 , A61K31/4439
CPC classification number: A61K9/0051 , A61K45/06 , A61P27/02 , A61K31/4439
Abstract: The invention relates to a sustained release biodegradable ocular implant containing a tyrosine kinase inhibitor dispersed in a hydrogel for the treatment of a retinal disease for an extended period of time.
-
12.发明公开公开(公告)号：US20230338281A1
公开(公告)日：2023-10-26
申请号：US18020544
申请日：2021-09-23
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Charles D. BLIZZARD , Rami EL-HAYEK , Michael GOLDSTEIN , Peter JARRETT , Andrew VANSLETTE
CPC classification number: A61K9/0051 , A61K9/06 , A61K49/0039 , A61K49/0056 , A61K38/13 , A61P27/02
Abstract: Provided herein are sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent, methods of treating or preventing an ocular disease in a subject in need thereof by administering such inserts as well as methods of manufacturing such inserts.
-
公开(公告)号：US20230172751A1
公开(公告)日：2023-06-08
申请号：US17896434
申请日：2022-08-26
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Noah Silverberg , Mark Silverberg
CPC classification number: A61F9/00772 , A61L31/148 , A61L31/04 , A61L2430/16 , A61K9/0048
Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.
-
公开(公告)号：US20230118774A1
公开(公告)日：2023-04-20
申请号：US17991762
申请日：2022-11-21
Applicant: Ocular Therapeutix, Inc.
Inventor： Charles D. Blizzard , Arthur Driscoll , Rami El-Hayek , Michael Goldstein , Joseph Iacona , Peter Jarrett , Timothy S. Jarrett , Erica Kahn , Zachary Lattrell
IPC: A61K9/00 , A61K9/06 , A61K31/4427 , A61K47/34 , A61P27/02 , A61K31/4439
Abstract: The invention relates to a sustained release biodegradable ocular implant containing a tyrosine kinase inhibitor dispersed in a hydrogel for the treatment of a retinal disease for an extended period of time.
-
15.发明申请公开(公告)号：US20250057759A1
公开(公告)日：2025-02-20
申请号：US18824391
申请日：2024-09-04
Applicant: Ocular Therapeutix, Inc.
Inventor： Charles D. Blizzard , Rami El-Hayek , Michael Goldstein , Peter Jarrett , Andrew Vanslette
Abstract: Provided herein are sustained release biodegradable intracanalicular insert comprising a hydrogel and cyclosporine, methods of treating or preventing an ocular disease in a subject in need thereof by administering such inserts as well as methods of manufacturing such inserts.
-
Patent Agency Ranking
公开(公告)号：US20240148553A1
公开(公告)日：2024-05-09
申请号：US18387612
申请日：2023-11-07
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Noah Silverberg , Mark Silverberg
CPC classification number: A61F9/00772 , A61L31/04 , A61L31/148 , A61K9/0048 , A61L2430/16
Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.
-
公开(公告)号：US20240042713A1
公开(公告)日：2024-02-08
申请号：US18273145
申请日：2022-12-06
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Peter JARRETT , Rami EL-HAYEK , Erica KAHN , Dinesh HASWANI , Eric DICKINSON , Timothy S. JARRETT , Michael MCGRATH
IPC: B29D11/00 , A61K31/573 , A61K9/00
CPC classification number: B29D11/0074 , A61K31/573 , A61K9/0051 , B29K2071/02
Abstract: The present invention is directed to a method of preparing a sustained release biodegradable ocular insert or implant comprising melt extruding or injection molding a polymer composition and an active agent to form an insert or implant suitable for administration to the body. e.g., ocular administration. The method comprises feeding the polymer composition and the active into an extruder; mixing the components in the extruder; extruding a strand; and cutting the strand into unit dose inserts or implants.
-
公开(公告)号：US20230040637A1
公开(公告)日：2023-02-09
申请号：US17880175
申请日：2022-08-03
Applicant: Ocular Therapeutix, Inc.
Inventor： Peter Jarrett , Rami El-Hayek , Timothy S. Jarrett , Zachary Lattrell , Arthur Driscoll , Charles D. Blizzard
IPC: A61K9/00 , A61K31/4439
Abstract: Provided herein are sustained-release biodegradable ocular hydrogel implants which are useful in the treatment of certain ocular conditions.
-
公开(公告)号：US11559429B1
公开(公告)日：2023-01-24
申请号：US17952218
申请日：2022-09-24
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Noah Silverberg , Mark Silverberg
Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.
-
公开(公告)号：US20230020148A1
公开(公告)日：2023-01-19
申请号：US17952218
申请日：2022-09-24
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Noah Silverberg , Mark Silverberg
Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.
-
-
-
-
-
-
-
-
-
Search Results
49
records
(took 0.017 seconds)
