公开(公告)号：US11837357B2

公开(公告)日：2023-12-05

申请号：US17727476

申请日：2022-04-22

Applicant: Fenwal, Inc.

Inventor： Brian C. Case ,  Lan T. Nguyen ,  Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: G16H40/60 ,  G16H10/60 ,  A61M1/34 ,  A61B34/10 ,  G06F21/31 ,  G08B3/10 ,  G08B5/22

CPC classification number: G16H40/60 ,  A61B34/10 ,  A61M1/34 ,  A61M1/3403 ,  G06F21/31 ,  G08B3/10 ,  G08B5/22 ,  G16H10/60 ,  H05K999/99 ,  A61M2205/33 ,  A61M2205/3334

Abstract: A system and method for collecting plasma includes drawing whole blood from a donor, combining anticoagulant with the whole blood from the donor, separating the whole blood into a plasma product and a second blood component and sending the plasma product to a collection container. A controller receives parameters over a network from a remote computer, receives a user input to confirm the a parameter and/or procedure, determines a target volume for plasma product and/or raw plasma based on the parameters and, in response to confirming the donor, controls the system to collect the plasma using draw and return phases.

公开(公告)号：US20230321334A1

公开(公告)日：2023-10-12

申请号：US18130503

申请日：2023-04-04

Applicant: Fenwal, Inc.

Inventor： Samantha M. Planas ,  Kyungyoon Min ,  Amit J. Patel ,  Thomas Gniadek

IPC: A61M1/36

CPC classification number: A61M1/3693 ,  A61M2205/3379

Abstract: A blood separation device has a controller configured to execute a first and a second version of a blood separation procedure. Information regarding a blood source is analyzed to determine whether to implement the first version of the procedure or the second version. This may include an analysis of the age, weight, and/or sex of the blood source, along with whether the blood source has previously been the subject of a blood separation procedure. The second version may allow for a greater percentage of the blood or red blood cells of the blood source to be outside of the body of the blood source (in a fluid flow circuit mounted to the device) at any time during the procedure. The second version may also or alternatively allow for a higher blood cell separation efficiency than the first version, along with separating the blood in a larger blood separation chamber.

公开(公告)号：US20230181807A1

公开(公告)日：2023-06-15

申请号：US18109547

申请日：2023-02-14

Applicant: FENWAL, INC.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: A61M1/34 ,  A61M1/36 ,  G01N33/48 ,  A61M1/38 ,  G16H10/60

CPC classification number: A61M1/3496 ,  A61M1/3672 ,  G01N33/48 ,  A61M1/3616 ,  A61M1/3643 ,  A61M1/38 ,  A61M1/382 ,  A61M1/385 ,  G16H10/60 ,  A61M2202/0415 ,  A61M2205/3379 ,  A61M2230/207 ,  A61M2205/3393 ,  A61M2205/502 ,  A61M2205/505

Abstract: A method of collecting plasma includes receiving donor parameters at a controller of a plasma collection device electronically from a donor management system. The method includes storing a target volume for raw plasma which is based at least in part on donor height and weight used to calculate total donor blood volume, the target volume for raw plasma based on the total donor blood volume. The method includes setting the target volume for raw plasma and controlling the plasma collection device to operate draw and return phases to withdraw whole blood from a donor and separate the whole blood into the plasma product and a second blood component comprising red blood cells and to return the second blood component to the donor. The controller operates the draw and return phases until a volume of raw plasma in the collection container equals the target volume of raw plasma.

公开(公告)号：US20220409799A1

公开(公告)日：2022-12-29

申请号：US17848821

申请日：2022-06-24

Applicant: Fenwal, Inc.

Inventor： Benjamin E. Kusters ,  Richard I. Brown ,  Kyungyoon Min

IPC: A61M1/36 ,  A61M1/38 ,  B04B11/02 ,  B04B5/04 ,  B01D36/04

Abstract: A processing device includes a pump system, a valve system, a centrifuge, and a controller. A fluid flow circuit is mounted to the device to execute a procedure in which whole blood is processed into a red blood cell product, a plasma product, and a platelet concentrate product. The blood is first separated into red blood cells, buffy coat, and plasma using the centrifuge, with the red blood cells and plasma being removed from the centrifuge, while the buffy coat remains in the centrifuge. The fluid remaining in the centrifuge is circulated through the centrifuge to form a homogenous mixture. Once the mixture is formed, it is separated in the centrifuge into platelet concentrate and red blood cells. A platelet product is then collected by using whole blood or previously collected red blood cells to push the platelet concentrate from the centrifuge to a collection container.

公开(公告)号：US11517919B2

公开(公告)日：2022-12-06

申请号：US16880022

申请日：2020-05-21

Applicant: Fenwal, Inc.

Inventor： Benjamin E. Kusters ,  Kyungyoon Min

IPC: B04B5/04 ,  B01D63/16 ,  B04B13/00

Abstract: A blood separation system is provided that includes a blood separation device that includes a centrifugal separator and a spinning membrane separator drive unit incorporated into a common case and a fluid flow circuit having both a separation chamber configured to be mounted in the centrifugal separator of the blood separation device and a spinning membrane separator configured to be received in the spinning membrane separator drive unit. In an exemplary procedure, the system is used to collect concentrated platelets and/or concentrated platelets and plasma, and to further permit harvesting of the mononuclear cells from the centrifugal separator at the conclusion of platelet collection, and transfer of the mononuclear cells to the spinning membrane separator.

公开(公告)号：US20220351851A1

公开(公告)日：2022-11-03

申请号：US17865038

申请日：2022-07-14

Applicant: Fenwal, Inc.

Inventor： Brian C. Case ,  Jonathan Prendergast ,  John W. Barry, JR. ,  Kyungyoon Min ,  Christopher D. Gassman ,  Daryl Richard Calhoun

IPC: G16H40/63 ,  G06Q10/10 ,  G16H10/60 ,  G06T11/20 ,  G06Q10/08 ,  G16H40/67

Abstract: A system and method for collecting whole blood from blood donors includes first and second whole blood collection devices disposed at different blood donation centers. A remote server computer is in communication with the blood collection devices. The whole blood collection devices transfer donation procedure information to the remote server. The remote server computer facilitates retrieval of the donation procedure information at a handheld computing device. The donation procedure information includes data based on product volume collected and data indicating performance of operators of the whole blood collection devices. The handheld computing device displays a number of whole blood units collected. Blood collection can be improved using the donation procedure information.

公开(公告)号：US11465160B2

公开(公告)日：2022-10-11

申请号：US16327358

申请日：2017-09-15

Applicant: Fenwal, Inc.

Inventor： Kyungyoon Min ,  Benjamin E. Kusters ,  Richard I. Brown ,  Mark J. Brierton

IPC: B04B5/04 ,  A61M1/36 ,  A61M1/02 ,  A61M1/26 ,  B01D36/04 ,  B01D63/16 ,  B04B11/02 ,  B04B13/00

Abstract: Systems and methods are provided for separating blood into two or more components. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit incorporated into a common case, which allows for fluid separation by two different methods. Depending on the separation procedure to be carried out, the fluid flow circuit paired with the blood separation device may include only one separation chamber configured to be mounted to the centrifugal separator or spinning membrane separator drive unit or two separation chambers, with one being mounted to the centrifugal separator and the other to the spinning membrane separator drive unit. The system may be used to separate and collect any combination of red blood cells, plasma, and platelets.

公开(公告)号：US20220280708A1

公开(公告)日：2022-09-08

申请号：US17825918

申请日：2022-05-26

Applicant: Fenwal, Inc.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: A61M1/34 ,  A61M1/36 ,  G01N33/48 ,  A61M1/38 ,  G16H10/60

Abstract: A system for collecting plasma comprises a separator to separate whole blood from a donor into a plasma product and red blood cells, an anticoagulant line to introduce anticoagulant to the whole blood, a touchscreen, and a controller. The controller is configured to receive donor parameters electronically from a donor management system. The controller is configured to use a target volume for plasma product and/or raw plasma which is based at least in part on donor height and weight used to calculate total donor blood volume, the target volume for plasma product and/or raw plasma based on the total donor blood volume. The controller is configured to control the system to operate at least three draw and return phases to withdraw whole blood from a donor and separate the whole blood into the plasma product and the red blood cells and to return the red blood cells to the donor.

公开(公告)号：US20220260408A1

公开(公告)日：2022-08-18

申请号：US17627245

申请日：2020-07-16

Applicant: Fenwal, Inc.

Inventor： James Madsen ,  Kyungyoon Min

IPC: G01G13/26 ,  G01G13/00

Abstract: A system for splitting a fluid includes a source support configured to support a source container of a fluid flow circuit and at least one satellite support, with each satellite support configured to support a different satellite container fluidly connected to the source container. A weight scale is associated with each of the supports. The system also includes a clamp system and a controller. The controller is configured to control each weight scale to measure a combined weight of the container and the contents of the container supported by the support associated with the weight scale. The controller is configured to control the clamp system to selectively allow and prevent fluid flow from the source container to each satellite container based at least in part upon the weights measured by each weight scale. Fluid flow continues until the contents of each container have reached a target volume.

公开(公告)号：US20220234303A1

公开(公告)日：2022-07-28

申请号：US17580684

申请日：2022-01-21

Applicant: Fenwal, Inc.

Inventor： James Madsen ,  Kyungyoon Min ,  Mark J. Brierton ,  Tom Westberg

IPC: B29C65/74 ,  F16L47/02 ,  G05D23/22 ,  B29C65/18 ,  B29C65/00

Abstract: A sterile connection device includes first and second carriages. The first carriage defines a first portion of a proximal slot and a first portion of a distal slot, while the second carriage defines second portions of the proximal and distal slots. A controller executes a sterile connection procedure in which a solid cutting blade is heated, followed by the heated blade being moved to a cutting position to cut sealed proximal and distal tubes received by the slots. The second carriage moves proximally or distally with respect to the first carriage so as to align the cut ends of the tubes. The heated blade then moves out of the cutting position, followed by the first carriage moving toward the second carriage so as to press the cut ends of the tubes into contact with each other so as to sterilely connect the cut ends and define a joined tube.