-
公开(公告)号:US06825930B2
公开(公告)日:2004-11-30
申请号:US10163233
申请日:2002-06-04
Applicant: Paul J. Cronin , Daniel Orband , Stephen D. Fantone , Peter J. Miller
Inventor: Paul J. Cronin , Daniel Orband , Stephen D. Fantone , Peter J. Miller
IPC: F21V900
CPC classification number: G01J3/10 , G01J3/2823 , G01J2003/1282 , G01N21/255 , G01N2201/062 , G01N2201/0633 , G01N2201/0635 , G01N2201/0638
Abstract: The invention features a multi-spectral microscopy system for illuminating a sample with light of a selectable spectral content and generating an image of the sample in response to the illumination. The multi-spectral microscopy system includes a multispectral illuminator that provides output radiation having the selectable spectral content. A preferred set of optical arrangements for the multispectral illuminator generates the output radiation so that the spectral content of the output radiation is substantially uniform across its transverse profile. Furthermore, the multispectral illuminator can include monitoring optics and a corresponding detector array that independently monitors the output in each spectral band of the radiation produced by the multispectral illuminator. The monitoring provides calibration, feedback, and/or source aging information to insure robust and reliable performance for the multispectral illuminator. The multi-spectral microscopy system also includes a microscope which illuminates the sample with light derived from the output of the multispectral illuminator, and beam modification optics, which modify the output from the lamp prior to the microscope to increase the light efficiency of the microscope and fully exploit field of view and resolution of the microscope.
Abstract translation: 本发明的特征在于一种多光谱显微镜系统,用于利用可选光谱含量的光照射样品,并响应于照明产生样品的图像。 多光谱显微镜系统包括多光谱照明器,其提供具有可选光谱含量的输出辐射。 用于多光谱照明器的优选的一组光学装置产生输出辐射,使得输出辐射的光谱含量在其横向轮廓上基本上是均匀的。 此外,多光谱照明器可以包括监视光学器件和相应的检测器阵列,其独立地监视由多光谱照明器产生的辐射的每个光谱带中的输出。 监控提供校准,反馈和/或源老化信息,以确保多光谱照明器的稳健可靠的性能。 多光谱显微镜系统还包括用来自多光谱照明器的输出的光照射样品的显微镜以及在显微镜之前改变来自灯的输出的光束修改光学器件,以提高显微镜的光效率, 充分利用显微镜的视野和分辨率。
-
公开(公告)号:US20240361234A1
公开(公告)日:2024-10-31
申请号:US18309390
申请日:2023-04-28
Applicant: Thermo Electron Scientific Instruments LLC
Inventor: Julian Irwin , Jeffrey Peter Wong
IPC: G01N21/31
CPC classification number: G01N21/31 , G01N2201/0633 , G01N2201/0634
Abstract: A spectrograph includes a base, a first optic mounted with respect to the base, a second optic mounted with respect to the base, and a third optic mounted with respect to the base. A first relative position between the first optic and the second optic is adjustable about a first pivot axis. A second relative position between the second optic and the third optic is adjustable about a second pivot axis independently from the adjustability of the relative position between the first optic and the second optic. The second pivot axis is substantially coincident with the first pivot axis, and a distance between the third optic and the second optic is fixed during adjustment of the second relative position.
-
公开(公告)号:US20240344980A1
公开(公告)日:2024-10-17
申请号:US18301486
申请日:2023-04-17
Applicant: The Boeing Company
Inventor: Brian Gunther , James Thaddeus Wegner , Jeffery Thomas Murphy
CPC classification number: G01N21/55 , G02B26/0816 , G01N2201/021 , G01N2201/06113 , G01N2201/0633 , G01N2201/0637
Abstract: A reflectometer configured to test a sample. The reflectometer includes a light source that emits a light beam to the sample that is placed on a sample holder. The reflectometer focuses the light beam to a reduced spot size on the sample. The reflectometer is configured to view structure/defects in the sample using a detector that is downstream from the sample.
-
194.
公开(公告)号:US12092568B2
公开(公告)日:2024-09-17
申请号:US17049833
申请日:2019-04-12
Applicant: Meon Medical Solutions Gmbh & Co KG
Inventor: Herfried Huemer , Arnold Bartel , Stefan Gulo , Patrick Kraus-Füreder , Robert Scholz-Mareich , Wolfgang Sprengers
CPC classification number: G01N21/31 , B01L3/5085 , G01N21/0303 , B01L2300/0654 , B01L2300/0829 , B01L2300/0832 , B01L2300/168 , G01N2021/0389 , G01N2201/062 , G01N2201/0633
Abstract: Aspects of the present disclosure are directed to, for example, an optical measurement unit for obtaining measurement signals from liquid media which are present in cuvettes lined up next to one another. In one embodiment, the optical measurement unit includes a light-supplying unit for emitting an inlet radiation into the cuvettes, and a detection unit for detecting a measurement radiation exiting from the cuvettes and for converting the measurement radiation into an electrical measurement signal. In such an embodiment, the light-supplying unit has a plurality of LED light sources which emit in a spectrally different manner in the UV/VIS/NIR wavelength range, and wherein the detection unit includes at least one photodiode fixedly assigned to each cuvette of a cuvette array.
-
公开(公告)号:US12085501B2
公开(公告)日:2024-09-10
申请号:US17753395
申请日:2020-06-11
Applicant: ALEADER VISION TECHNOLOGY CO., LTD.
Inventor: Jinfeng Wang , Yuan Luo , Jing He , Guanzhong Kou
IPC: G01N21/31
CPC classification number: G01N21/31 , G01N2201/0633 , G01N2201/0635
Abstract: A spectral confocal measurement device includes a light source portion, configured to emit a broad-spectrum light beam with a certain wavelength range in a first predetermined path; an optical sampling portion, configured to converge the broad-spectrum light beam emitted from the light source portion on different measurement surfaces of an object to be measured, and output a reflected light in a second predetermined path that is different from a reverse direction of the first predetermined path; and a measurement portion, configured to receive and process the reflected light from the optical sampling portion to obtain a measurement result. The device can improve measurement accuracy and reduce production costs. In addition, a spectral confocal measurement method is also provided.
-
公开(公告)号:US12072290B2
公开(公告)日:2024-08-27
申请号:US17772265
申请日:2020-09-11
Inventor: Stanley Michael Angel , Jerry Chance Carter
IPC: G01N21/65
CPC classification number: G01N21/65 , G01N2201/0633 , G01N2201/0635
Abstract: A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well.
-
公开(公告)号:US12061151B2
公开(公告)日:2024-08-13
申请号:US17613234
申请日:2020-05-27
Inventor: Ines Frese , Michael Maskos
IPC: G01N21/65
CPC classification number: G01N21/65 , G01N2201/06113 , G01N2201/0633 , G01N2201/129
Abstract: A method for detecting Raman scattered light using at least one interference filter and a detection unit, the Raman scattered light to be detected including an incoming scattered light signal, wherein the method includes the following steps: * a first filtered scattered light signal is generated by the application of a first transmission function to the incoming scattered light signal, the first transmission function being assigned to a first optical path length L1 through a first interference filter, and the first transmission function defining a first spectral band δλ1; * a second filtered scattered light signal is generated by the application of a second transmission function to the incoming scattered light signal, the second transmission function being assigned to a second optical path length L2≠L1 through the first interference filter or through a second interference filter, and second transmission function defining a second spectral band δλ2; and * the first and the second filtered scattered light signals are detected by the detection unit.
-
公开(公告)号:US12061149B2
公开(公告)日:2024-08-13
申请号:US17324423
申请日:2021-05-19
Applicant: YSI, INC.
Inventor: Kevin Flanagan
CPC classification number: G01N21/6456 , G01N21/4785 , G01N21/532 , G01N21/64 , G01N21/82 , G01N33/08 , G01N33/18 , H04N25/46 , G01N2021/6473 , G01N2021/6491 , G01N2201/061 , G01N2201/0633 , G01N2201/0636 , G01N2201/126 , G01N2201/12761 , G01N2201/12792
Abstract: A swept frequency fluorometer having a signal processor or processing module configured to:
receive signaling containing information about reflected light off one or more fluorescence species-of-interest in a liquid sample that is swept with light having a variable frequency range, the information including a characteristic optical frequency corresponding to a fluorescence species-of-interest in the liquid, and a characteristic/lifetime optical frequency corresponding to a distinct fluorescence lifetime in which the fluorescence species-of-interest remains in an excited state; and
provide corresponding signaling containing information about an identity of the fluorescence species-of-interest detected and distinguished from overlapping fluorescence species in the liquid using the characteristic/lifetime optical frequency, based upon the signaling received.-
公开(公告)号:US12050174B2
公开(公告)日:2024-07-30
申请号:US17259343
申请日:2019-07-19
Applicant: OMYA INTERNATIONAL AG
Inventor: Roger Bollström , Kai Max Hettmann
IPC: G01N21/3563 , B41M3/14 , B42D25/382
CPC classification number: G01N21/3563 , B41M3/14 , B42D25/382 , G01N2201/0633
Abstract: The present invention refers to method for detecting phosphate and/or sulphate salts on the surface of a substrate or within a substrate, use of a LWIR detecting device for detecting the intensity of electromagnetic radiation scattered and/or emitted reflection by phosphate and/or sulphate salts being present on and/or in a substrate, use of a substrate comprising phosphate and/or sulphate salts for providing information via electromagnetic radiation scattering and/or emission as well as a LWIR imaging system for detecting phosphate and/or sulphate salts on and/or within a substrate.
-
公开(公告)号:US12031917B2
公开(公告)日:2024-07-09
申请号:US18458988
申请日:2023-08-30
Applicant: Robert R. Alfano
Inventor: Robert R. Alfano , Sandra Mamani Reyes
CPC classification number: G01N21/65 , G01N2201/06113 , G01N2201/0633
Abstract: A method for obtaining a polarized orbital angular momentum Raman spectrum using vector vortex beams, includes the steps of emitting a polarized laser light from a laser source. The polarized laser light is passed through a narrow band filter that is then passed through a section of wave plates (quarter or half wave plate) to generate polarized light (linear, circular, radial and azimuthal), then through a q-plate (vortex retarder or spiral plate) to give a vortex structure topology carrying orbital angular momentum with a helical phase. The polarized vector vortex light is then directed to contact a sample, thereby producing a Raman scatter beam. The Raman scatter beam is passed back and collected into a spectrometer, thereby obtaining a Raman scattering spectrum of the sample to investigate the matching of the multipoles of the material and the multipoles of the light. A method for transmission with Multiple expansions of orbital angular momentum in rat cerebellum tissue is also disclosed. In general, we use polarized Laguerre-Gaussian vector vortex beams as a topology multipole model to describe and study the light matter interaction for Raman and transmission using the fact that the optical vortices and material can possess Multipoles denoted as L in form of monopole (L=0), dipole (L=1), quadrupole (L=2), octupole (L=3), hexidecapole (L=4) and higher orders. These multipoles can be involved with the matching up with the symmetry of the moments involved with vibrational states in Raman processes.
-
-
-
-
-
-
-
-
-