公开(公告)号：US11445947B2

公开(公告)日：2022-09-20

申请号：US16884747

申请日：2020-05-27

Applicant: BIOXYTECH RETINA, INC.

Inventor： Ali Basiri

IPC: G01J3/04 ,  A61B5/1455 ,  A61B3/14 ,  A61B5/00 ,  G06T7/00 ,  G06V10/60

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.

公开(公告)号：US11366014B2

公开(公告)日：2022-06-21

申请号：US16589371

申请日：2019-10-01

Applicant: KROHNE Messtechnik GmbH

Inventor： Thomas Fritsch

IPC: G01J3/50 ,  G01J3/04 ,  G01J3/02 ,  G01J3/18 ,  G01J3/10

Abstract: A spectrometer including at least one light-coupling element, a variable entrance slit, a dispersive element, a detector element and a control and evaluation unit. The object of providing a spectrometer having improved measuring characteristics is achieved in that the variable entrance slit is implemented by a first spatial modulation element including a plurality of pixels, wherein the individual pixels can be arranged independently of one another by the control and evaluation unit, wherein the individual pixels are arranged in order to implement the entrance slit during operation in such a manner that at least part of the light incident from the light-coupling element is passed on to the dispersive element.

公开(公告)号：US11268854B2

公开(公告)日：2022-03-08

申请号：US16677792

申请日：2019-11-08

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Seunghoon Han ,  Amir Arbabi ,  Andrei Faraon ,  Ehsan Arbabi ,  Hyeonsoo Park

IPC: G01J3/04 ,  G01J3/02 ,  G02B5/18

Abstract: A spectrometer includes a substrate; a slit which is provided on the substrate and through which light is incident onto the substrate; a metasurface including nanostructures that is configured to reflect and focus the light incident thereon through the slit, at different angles based on respective wavelengths; and a sensor which is provided on one side of the substrate that is opposite to another side of the substrate at which the metasurface is disposed, and configured to receive the light from the metasurface.

公开(公告)号：US11112392B2

公开(公告)日：2021-09-07

申请号：US16597191

申请日：2019-10-09

Applicant: Waters Technologies Corporation

Inventor： Anthony C. Jeannotte ,  Daniel Gillund ,  Aditya Shankar Prasad ,  Saksham Saxena

IPC: G01N30/95 ,  G01J3/02 ,  G01J3/42 ,  G01N30/74 ,  G01N21/31 ,  G01J3/00 ,  G01J3/28 ,  G01J3/10 ,  G01J3/04 ,  G01J3/18 ,  G01J1/42 ,  G02B26/08 ,  G01J3/12 ,  G01N21/05

Abstract: A detector for use in liquid chromatography is provided. The detector includes a light delivery system comprising a light source that emits one or more spectral lines of light of a light spectrum. The detector has an entrance slit configured to receive the one or more spectral lines of light and a wavelength selection module comprising a digital micro-mirror device. The digital micro-mirror device is configured to redirect the one or more spectral lines of light to a flow cell. The flow cell is optically connected to the wavelength selection module.

公开(公告)号：US11002601B2

公开(公告)日：2021-05-11

申请号：US16484449

申请日：2018-02-01

Applicant: NANOPHOTON CORPORATION

Inventor： Katsumasa Fujita

IPC: G01J3/04 ,  G01J3/28 ,  G01J3/36 ,  G01J3/44 ,  G01N21/27 ,  G01N21/65 ,  G02B21/06

Abstract: A spectroscopic microscope according to the present embodiment includes a light source that generates laser light that enters a sample, a multi-slit part having a plurality of slits through which signal light branched by the edge filter passes, the slits being arranged in the slit width direction, and a spectrometer that disperses the signal light having passed through the slits in the dispersion direction intersecting the slit length direction and detects the signal light with a two-dimensional array photodetector.

公开(公告)号：US10571334B2

公开(公告)日：2020-02-25

申请号：US15844069

申请日：2017-12-15

Applicant: Horiba Instruments Incorporated

Inventor： Harry Jerome Oana ,  Xiaomei Tong ,  Ronald Joseph Kovach

IPC: G01J3/02 ,  G01J3/04 ,  G01J3/18 ,  G01J3/40 ,  G01J3/42

Abstract: An optical system includes a spectrograph having a concave diffraction grating and a detector. An aperture is selectively positioned by an associated actuator or positioning mechanism either into, or out of, an optical path of the input light beam downstream of a sample and prior to entering the spectrograph. A slit plate having a plurality of different size entrance slits is positioned downstream of the aperture and movable by an associated actuator or positioning mechanism to position one of the plurality of entrance slits in the optical path of the input light beam. A controller coupled to the detector and the actuators is configured to control the actuators to selectively position the aperture and the slit plate to provide a selectable resolution of the spectrograph. The aperture setting and slit plate setting may be determined from a lookup table in response to a request for finer or coarser spectral resolution.

公开(公告)号：US20190186992A1

公开(公告)日：2019-06-20

申请号：US16225121

申请日：2018-12-19

Applicant: Analytik Jena AG

Inventor： Stefan Münch ,  Michael Okruss

IPC: G01J3/04 ,  G01J3/18 ,  G01J3/02 ,  G01J3/22

Abstract: The present disclosure discloses a spectrometer arrangement including an entrance-slit group including a slit wheel and a slit mask for introducing radiation into and for limiting the optical field of the spectrometer arrangement, a first dispersive element for spectrally decomposing the radiation in a main dispersion direction, and a second dispersive element for spectrally decomposing the radiation in a transverse dispersion direction that forms an angle with the main dispersion direction to yield a two-dimensional spectrum. The slit wheel is mounted rotatably about an axis of rotation and has a falcate opening having a width that changes depending on the angle. The slit mask includes an opening that is longer than a largest width of the falcate opening such that radiation radiates through the falcate opening of the slit wheel and the opening of the slit mask. The present disclosure further includes a corresponding method and an optical component group.

公开(公告)号：US20190170580A1

公开(公告)日：2019-06-06

申请号：US16204541

申请日：2018-11-29

Applicant: Bruker AXS GmbH

Inventor： Alexej WITZIG ,  Martin VAN STUIJVENBERG ,  Rainer SIMONS

IPC: G01J3/28 ,  G01J3/18 ,  G01J3/04 ,  G01J3/443

Abstract: An optical emission spectrometer has an excitation device for a sample to be examined, a dispersive element for spectrally decomposing light emitted by an excited sample, a multiplicity of photodiodes, which are arranged such that different spectral components of the emitted, decomposed light are detectable with different photodiodes, and a multiplicity of electronic readout systems for the photodiodes. A respective electronic readout system has a charge storage assembly comprising a plurality of individual charge storage devices, wherein the charge storage devices are interconnectable in cascading fashion, with the result that charges flowing in from an associated photodiode successively fill the charge storage devices. The respective electronic readout system can be used to read the charges of the individual charge storage devices of the charge storage assembly and/or the charges of subsets of the charge storage devices of the charge storage assembly.

公开(公告)号：US10247607B2

公开(公告)日：2019-04-02

申请号：US15714454

申请日：2017-09-25

Applicant: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.

Inventor： Heinrich Grueger ,  Jens Knobbe ,  Tino Puegner

IPC: G01J3/18 ,  G01J3/02 ,  G01J3/04 ,  G01J3/06

Abstract: An optical arrangement for a spectral analysis system, a method for producing an optical arrangement for a spectral analysis system and a spectral analysis system are disclosed. In an embodiment the optical arrangement includes a carrier substrate having a placement area for a frame and a base area, and a diffraction grating movably arranged in the frame, wherein the frame is arranged on the placement area in an inclined placement position with respect to the base area so that the diffraction grating, arranged in a base position, is inclined with respect to the base area.

公开(公告)号：US20190004067A1

公开(公告)日：2019-01-03

申请号：US15993503

申请日：2018-05-30

Applicant: Becton, Dickinson and Company

Inventor： Scott Bornheimer ,  Edward Goldberg

IPC: G01N33/72 ,  G01J3/04 ,  G01J3/02 ,  G01N21/31

Abstract: Aspects of the present disclosure include methods and systems for assaying a sample for an analyte. Methods according to certain embodiments include illuminating a sample with a slit-shaped beam of light, detecting light transmitted through the sample, determining absorbance of the transmitted light at one or more wavelengths and calculating concentration of the analyte based on the absorbance to assay the sample for the analyte. Systems for practicing the subject methods are also described.