公开(公告)号：US08025915B2

公开(公告)日：2011-09-27

申请号：US11649361

申请日：2007-01-04

Applicant: Daniel Haines ,  Luis Burzio ,  Matthias Bicker ,  Robert Hormes ,  Horst Koller ,  Jasmina Buki ,  Hartmut Bauch ,  Manfred Lohmeyer

Inventor： Daniel Haines ,  Luis Burzio ,  Matthias Bicker ,  Robert Hormes ,  Horst Koller ,  Jasmina Buki ,  Hartmut Bauch ,  Manfred Lohmeyer

IPC: A61B10/00 ,  B05D7/22 ,  B29D22/00 ,  B29D23/00

CPC classification number: A61L27/34 ,  A61J1/05 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  B05D1/62 ,  B05D7/22 ,  Y10T428/13 ,  Y10T428/1307

Abstract: A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.

Abstract translation: 一种在药物包装上制备大分子威慑表面的方法。 特别地，本发明涉及通过将涂层或涂层直接施加到药物包装上来制备药物包装上的蛋白质威慑表面的方法，其减少蛋白质在药物包装上的吸附，同时不影响所含蛋白质溶液的活性 。

公开(公告)号：US07931955B2

公开(公告)日：2011-04-26

申请号：US10486056

申请日：2002-08-07

Applicant: Stephan Behle ,  Lutz Klippe ,  Matthias Bicker ,  Marten Walther

Inventor： Stephan Behle ,  Lutz Klippe ,  Matthias Bicker ,  Marten Walther

IPC: B32B7/02

CPC classification number: C23C16/401 ,  C23C16/045 ,  C23C16/30 ,  C23C16/405 ,  C23C16/515 ,  Y10T428/24967 ,  Y10T428/24975 ,  Y10T428/265 ,  Y10T428/31507 ,  Y10T428/31565 ,  Y10T428/31587 ,  Y10T428/31667

Abstract: A composite material having a substrate material and at least one barrier coating on one side of the substrate material. The barrier coating is plasma impulse chemical vapor deposited (PICVD) to the substrate material. The barrier coating includes at least one of material selected from the group consisting of SiOx, TiOx, SnOx, Si3Ny, Nb2Oy, and Al2Oy.

Abstract translation: 一种复合材料，其具有衬底材料和在衬底材料的一侧上的至少一个阻挡涂层。 阻挡涂层是等离子体脉冲化学气相沉积（PICVD）到基底材料。 阻挡涂层包括选自SiO x，TiO x，SnO x，Si 3 N y，Nb 2 O y和Al 2 O y的材料中的至少一种。

公开(公告)号：US20100231194A1

公开(公告)日：2010-09-16

申请号：US12719247

申请日：2010-03-08

Applicant: Hartmut Bauch ,  Matthias Bicker

Inventor： Hartmut Bauch ,  Matthias Bicker

IPC: G01R23/12

CPC classification number: H01J37/32935 ,  H01J37/32036 ,  H01J37/32348

Abstract: A method and a device (MON) for monitoring plasma-discharges during a surface treatment process are described. In this process electrodes within a gaseous medium are provided with an alternating voltage (UHV) for generating plasma. The monitoring device (MON) has a detector device (M1) for detecting a measurement signal (I) generated by the alternating voltage (UHV) within the gaseous medium, separating means (M2) for separating signal components above a preset frequency and evaluating means (M3) for evaluating the resulting separated signal components by comparing them with at least one preset reference. Preferably the generating of the plasma is achieved by dielectric barrier discharge and the electric current penetrating the medium, especially the dielectric displacement current, is measured as the measurement signal (I).

Abstract translation: 描述了用于在表面处理过程中监测等离子体放电的方法和装置（MON）。 在这个过程中，气体介质中的电极设置有用于产生等离子体的交流电压（UHV）。 监视装置（MON）具有用于检测由气体介质中的交流电压（UHV）产生的测量信号（I）的检测装置（M1），用于分离高于预设频率的信号分量的分离装置（M2） （M3），用于通过将它们与至少一个预设参考进行比较来评估所产生的分离的信号分量。 优选地，通过电介质阻挡放电实现等离子体的产生，并且测量穿透介质的电流，特别是介电位移电流作为测量信号（I）。

公开(公告)号：US07699933B2

公开(公告)日：2010-04-20

申请号：US10515609

申请日：2003-05-09

Applicant: Michael Lizenberg ,  Frank Lewis ,  Hartwig Müller ,  Klaus Vogel ,  Gregor Arnold ,  Stephan Behle ,  Andreas Lüttringhaus-Henkel ,  Matthias Bicker ,  Jürgen Klein

Inventor： Michael Lizenberg ,  Frank Lewis ,  Hartwig Müller ,  Klaus Vogel ,  Gregor Arnold ,  Stephan Behle ,  Andreas Lüttringhaus-Henkel ,  Matthias Bicker ,  Jürgen Klein

IPC: C23C16/00 ,  B05D7/22

CPC classification number: C23C16/54 ,  B05D1/62 ,  B08B7/00 ,  B08B9/426 ,  B29C49/421 ,  B29C2049/4221 ,  B29C2791/001 ,  B65D23/02 ,  B65G29/00 ,  B65G2201/0244 ,  C23C14/046 ,  C23C14/505 ,  C23C16/045 ,  C23C16/401 ,  C23C16/458 ,  C23C16/511 ,  H01J37/32733

Abstract: The invention relates to a method and a device which are used for the plasma treatment of work pieces. Said work piece is inserted into an at least partially evacuatable chamber of a treatment station (3) and the work piece is positioned inside the treatment station of retaining elements. At least one operating agent is at least partially impinged upon by a transporting device (44) which is displaced together with the treatment station on a closed and rotating transport path.

Abstract translation: 本发明涉及一种用于等离子体处理工件的方法和装置。 所述工件被插入到处理站（3）的至少部分可抽空的室中，并且工件位于保持元件的处理站内。 至少一个操作剂至少部分地被传送装置（44）撞击，传送装置（44）与处理站一起在封闭和旋转的传送路径上移动。

公开(公告)号：US07433752B2

公开(公告)日：2008-10-07

申请号：US11391172

申请日：2006-03-28

Applicant: Peter Eimann ,  Patrick Johannes ,  Felix Petry ,  Hartmut Eggert ,  Peter Woerner ,  Matthias Bicker

Inventor： Peter Eimann ,  Patrick Johannes ,  Felix Petry ,  Hartmut Eggert ,  Peter Woerner ,  Matthias Bicker

IPC: G06F19/00

CPC classification number: G05B19/056 ,  G05B2219/13015 ,  G05B2219/13106 ,  G05B2219/13144

Abstract: The controller and method of the invention generate control instructions for a rotary machine that coats bottles. Gas is supplied to processing stations holding the bottles via a pressure management system. The processing stations are centrally controlled by a programmable PLC or microcontroller with an input device and display terminal. Since rotary machines need to be controlled differently depending on the type of bottles and the type of coating, different programs should be interactively created using the input device and display terminal, which then control the individual components of the rotary machine and the processing stations during the coating process. This eliminates unnecessary errors resulting from preparation of the different programs individually by a normal user.

Abstract translation: 本发明的控制器和方法产生涂覆瓶子的旋转机器的控制指令。 通过压力管理系统将气体供给到容纳瓶的加工站。 处理站由具有输入设备和显示终端的可编程PLC或微控制器集中控制。 由于旋转机器需要根据瓶子的类型和涂层的类型进行不同的控制，所以应该使用输入设备和显示终端来交互地创建不同的程序，然后控制旋转机器和处理站的各个部件 涂层工艺。 这消除了由普通用户单独准备不同程序所导致的不必要的错误。

公开(公告)号：US20070148368A1

公开(公告)日：2007-06-28

申请号：US11527110

申请日：2006-09-25

Applicant: Gregor Arnold ,  Stephan Behle ,  Matthias Bicker ,  Andreas Luttringhaus-Henkel

Inventor： Gregor Arnold ,  Stephan Behle ,  Matthias Bicker ,  Andreas Luttringhaus-Henkel

IPC: C23C16/00 ,  H05H1/24

CPC classification number: H01L21/67745 ,  C23C16/045 ,  C23C16/509 ,  C23C16/54 ,  H01J37/32733

Abstract: In order to allow a continuous production process for the plasma treatment of workpieces, an apparatus for plasma treatment of workpieces is provided which comprises a transport device and a plasma generating device which injects electromagnetic energy into an area of the apparatus during operation, in which the transport device carries the workpieces through the area continuously.

Abstract translation: 为了允许用于工件的等离子体处理的连续制造工艺，提供了一种用于工件的等离子体处理的装置，其包括输送装置和等离子体产生装置，其在操作期间将电磁能注入到装置的区域中，其中 运输装置通过该区域连续运送工件。

公开(公告)号：US20060224257A1

公开(公告)日：2006-10-05

申请号：US11391172

申请日：2006-03-28

Applicant: Peter Eimann ,  Patrick Johannes ,  Felix Petry ,  Hartmut Eggert ,  Peter Woerner ,  Matthias Bicker

Inventor： Peter Eimann ,  Patrick Johannes ,  Felix Petry ,  Hartmut Eggert ,  Peter Woerner ,  Matthias Bicker

IPC: G05B15/00

CPC classification number: G05B19/056 ,  G05B2219/13015 ,  G05B2219/13106 ,  G05B2219/13144

Abstract: The invention relates to a device and a method for generating control instructions for a rotary machine, wherein processing stations are disposed on a rotary machine. In the preferred embodiment, the processing stations have holders for receiving bottles. Furthermore, gas is supplied via the processing stations and via the pressure management system. The processing stations can be controlled centrally by a PLC, by respectively one separate PLC or by specific microcontrollers. Said components can be programmed by code instructions. A further component of the device is an input and display terminal by which means the programs are created interactively. This is preferably a laptop with a windowed interface such as Windows®. Since rotary machines need to be controlled differently depending on the type of bottles and the type of coating, different programs should be created which then control the individual components of the rotary machine and the processing stations. As a result of the complexity of the control instructions and the associated liability to error in the programming, it is unreasonable for a normal user to create such a program which is generally based on a recipe.

Abstract translation: 本发明涉及一种用于产生旋转机器的控制指令的装置和方法，其中处理站设置在旋转机器上。 在优选实施例中，处理站具有用于接收瓶的保持器。 此外，气体经由处理站和压力管理系统供应。 处理站可以由PLC集中控制，分别由一个独立的PLC或特定的微控制器控制。 所述组件可以通过代码指令进行编程。 该装置的另一个部件是输入和显示终端，通过该输入和显示终端，这意味着程序是以交互方式创建的。 这优选地是具有窗口界面的笔记本电脑，例如Windows（R）。 由于旋转机器需要根据瓶子的类型和涂层的类型进行不同的控制，因此应该创建不同的程序，然后控制旋转机器和加工站的各个部件。 由于控制指令的复杂性和编程中与错误相关的责任，普通用户创建一般基于配方的程序是不合理的。

公开(公告)号：US10071397B2

公开(公告)日：2018-09-11

申请号：US13395602

申请日：2010-09-14

Applicant: Matthias Bicker ,  Hartmut Bauch ,  Manfred Lohmeyer

Inventor： Matthias Bicker ,  Hartmut Bauch ,  Manfred Lohmeyer

IPC: B05D5/08 ,  B05D3/14 ,  B05D7/22 ,  B05D1/00 ,  B05D3/04

CPC classification number: B05D5/083 ,  B05D1/62 ,  B05D3/0493 ,  B05D3/141 ,  B05D3/147 ,  B05D7/22 ,  B05D2201/02 ,  B05D2203/35

Abstract: A pharmaceutical packaging comprising a silicone-free lubricating film of crosslinked organic molecules. The method for producing the pharmaceutical packaging comprises: applying a silicone-free organic fluid as a film on a surface of a hollow substrate for the lubricating film; placing the substrate in a vacuum reactor; evacuating the vacuum reactor; generating an alternating electromagnetic field by an AC voltage source; and introducing the alternating electromagnetic field into the interior of the substrate, a field strength thereof in the gas which is present in or introduced into the evacuated cavity of the substrate being sufficient to cause a homogeneous glow discharge under the pressure prevailing in the cavity of the substrate.

公开(公告)号：US07744790B2

公开(公告)日：2010-06-29

申请号：US10485979

申请日：2002-08-07

Applicant: Stephan Behle ,  Markus Kuhr ,  Marten Walther ,  Detlef Wolff ,  Matthias Bicker

Inventor： Stephan Behle ,  Markus Kuhr ,  Marten Walther ,  Detlef Wolff ,  Matthias Bicker

IPC: B29C51/10

CPC classification number: B05D1/62 ,  B05D7/227 ,  B29C45/0053 ,  B29C45/1703 ,  B29C2045/0079

Abstract: A process for simultaneously coating and forming a body. The process includes moving two mold halves into contact with one another; introducing an injection-molding material into the mold halves so that a molding is formed; evacuating the molding; admitting a gas into the molding; igniting a plasma in the molding so that a coating is deposited on the inner side of the molding; and moving the mold halves apart so that the molding drops out.

Abstract translation: 同时涂覆和形成身体的方法。 该过程包括使两个半模彼此接触; 将注射成型材料引入到半模中，从而形成模制品; 抽真空模具; 将气体进入模制品; 在模制品中点燃等离子体，使得涂层沉积在模制品的内侧; 并将半模分开，使模具脱落。

公开(公告)号：US07399500B2

公开(公告)日：2008-07-15

申请号：US10637779

申请日：2003-08-07

Applicant: Matthias Bicker ,  Stephan Behle ,  Lutz Klippe ,  Andreas Lüttringhaus-Henkel ,  Gregor Arnold

Inventor： Matthias Bicker ,  Stephan Behle ,  Lutz Klippe ,  Andreas Lüttringhaus-Henkel ,  Gregor Arnold

IPC: C23C16/511 ,  H05H1/24

CPC classification number: B05D7/50 ,  B05D1/60 ,  B05D1/62 ,  B05D7/02 ,  C23C16/0272 ,  C23C16/045 ,  C23C16/30 ,  C23C16/401 ,  C23C16/515 ,  Y10T428/31504 ,  Y10T428/31681

Abstract: A process for applying alternating layers by chemical vapor deposition comprises the process steps of depositing an adhesion-promoter layer on a substrate and applying a barrier layer. Alternating layers comprising organic and inorganic materials are deposited alternately, and in this process the coating time for application of the adhesion-promoter layer is between 0.05 s and 4.0 s and the coating time for application of the inorganic barrier layer is between 0.1 s and 6.0 s. A composite material is also produced using the process.

Abstract translation: 通过化学气相沉积施加交替层的方法包括在衬底上沉积粘合促进剂层并施加阻挡层的工艺步骤。 包含有机和无机材料的交替层交替沉积，并且在该过程中，涂覆粘合促进剂层的涂布时间为0.05s至4.0s，并且施加无机阻挡层的涂布时间为0.1s至6.0 s。 还使用该方法生产复合材料。