公开(公告)号：US20210145337A1

公开(公告)日：2021-05-20

申请号：US17100540

申请日：2020-11-20

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Michael Chen ,  Pey-Jiun Ko ,  Tammy Burd ,  Adrit Lath ,  Patricia McHale

IPC: A61B5/15 ,  A61B5/157 ,  A61B10/00 ,  A61B5/151 ,  A61B5/154 ,  B01L3/00

Abstract: Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.

公开(公告)号：US11008628B1

公开(公告)日：2021-05-18

申请号：US14490653

申请日：2014-09-18

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Timothy Smith ,  Samartha Anekal ,  James R. Wasson ,  Daniel L. Young ,  Chinmay Pangarkar

IPC: C12Q1/70 ,  G01N33/569 ,  B01L7/00 ,  B01L3/00

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

公开(公告)号：US10989724B1

公开(公告)日：2021-04-27

申请号：US15664108

申请日：2017-07-31

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Daniel Young ,  Samartha Anekal ,  Timothy Smith ,  James R. Wasson ,  Chinmay Pangarkar

IPC: G01N15/00 ,  G01N21/00 ,  G01N35/04 ,  G01J3/28 ,  G01N15/14

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US10920284B2

公开(公告)日：2021-02-16

申请号：US15159399

申请日：2016-05-19

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Chandan Shee ,  Clarissa Lui

IPC: C12Q1/689 ,  C12Q1/04 ,  G01N33/53 ,  G01N33/569

Abstract: Systems and methods for determining pathogens and antimicrobial resistance of pathogens in a sample are provided.

公开(公告)号：US20220196657A1

公开(公告)日：2022-06-23

申请号：US17516462

申请日：2021-11-01

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Ian Gibbons

IPC: G01N33/569 ,  B01L3/00 ,  C12Q1/70 ,  G01N33/543

Abstract: The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.

公开(公告)号：US11158429B2

公开(公告)日：2021-10-26

申请号：US15952957

申请日：2018-04-13

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Ian Gibbons ,  Daniel Young ,  Seth G. Michelson

IPC: G16H50/50 ,  G16H50/70 ,  G16H50/80 ,  G16H50/20 ,  G06F19/00

Abstract: The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources.

公开(公告)号：US11143647B2

公开(公告)日：2021-10-12

申请号：US15160491

申请日：2016-05-20

Applicant: Labrador Diagnostics LLC

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/53 ,  G01N33/543 ,  B01J19/00 ,  B01L3/02 ,  B01L3/00 ,  G01N35/02 ,  B01L9/00 ,  G16H10/40 ,  G01N1/38 ,  G01N33/569 ,  A61B5/15 ,  A61B5/151 ,  G01N35/10 ,  B01L7/00 ,  G01N33/68 ,  G01N33/94 ,  G01N35/00 ,  G01N33/574 ,  A61B10/00 ,  A61B10/02

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

公开(公告)号：US11139084B2

公开(公告)日：2021-10-05

申请号：US15246401

申请日：2016-08-24

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Ian Gibbons ,  Daniel Young ,  Seth G. Michelson

IPC: G16H50/50 ,  G16H50/80 ,  G16H50/70 ,  G16H50/20 ,  G06F19/00

Abstract: The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources.

公开(公告)号：US10908093B2

公开(公告)日：2021-02-02

申请号：US14867271

申请日：2015-09-28

Applicant: Labrador Diagnostics LLC

Inventor： Ian Gibbons ,  Chengwang Wang ,  Shaunak Roy ,  Elizabeth A. Holmes

IPC: G01N21/76 ,  G01N33/53 ,  B01L3/00 ,  A61B5/151 ,  A61B5/157 ,  A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61B5/15 ,  G01N33/50 ,  A61B5/155 ,  G01N33/543 ,  A61B5/1495

Abstract: The present invention provides methods of calibrating a fluidic device useful for detecting an analyte of interest in a bodily fluid. The invention also provides methods for assessing the reliability of an assay for an analyte in a bodily fluid with the use of a fluidic device. Another aspect of the invention is a method for performing a trend analysis on the concentration of an analyte in a subject using a fluidic device.

公开(公告)号：US20200326356A1

公开(公告)日：2020-10-15

申请号：US16853594

申请日：2020-04-20

Applicant: Labrador Diagnostics LLC

Inventor： James Wasson ,  Pey-Jiun Ko ,  Joy Roy ,  Elizabeth A. Holmes

IPC: G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  B01L3/00 ,  B01L9/06 ,  B01L9/00 ,  G01N15/14 ,  B01L7/00 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N33/569 ,  G01N33/80 ,  G01N21/25 ,  G01N33/543 ,  B01L3/02 ,  G01N21/27 ,  C12Q1/42 ,  C12Q1/52 ,  G01N33/62 ,  G01N33/68 ,  G01N33/92

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.