公开(公告)号：US20080043235A1

公开(公告)日：2008-02-21

申请号：US11894829

申请日：2007-08-22

Applicant: Mark Oldham ,  Eric Nordman ,  Richard Reel ,  John Shigeura ,  Janice Shigeura

Inventor： Mark Oldham ,  Eric Nordman ,  Richard Reel ,  John Shigeura ,  Janice Shigeura

IPC: G01N21/00

CPC classification number: G01N21/6456 ,  B82Y10/00 ,  B82Y20/00 ,  G01N27/44721 ,  G01N2021/6417 ,  G01N2021/6419 ,  G01N2021/6471 ,  G01N2201/0628

Abstract: Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the detection zone with radiation; a detector capable of collecting at least one charge corresponding to an emission beam emitted from the detection zone, the detector having an output; and a time delay integration system coupled to the detector for effecting time delay integration of the at least one charge by accumulating the at least one charge before reading the at least one charge at the output of the detector. Various embodiments provide an apparatus with a multi-notch filter. Various embodiments provide a solid state laser, a micro-wire laser, or an organic light-emitting diode as a irradiation source.

Abstract translation: 提供了用于检测样品中分析物的装置和方法。 该装置可以包括：具有检测区域的一个或多个通道; 设置用于辐射照射检测区域的一个或多个照射源; 检测器，其能够收集对应于从所述检测区域发射的发射光束的至少一个电荷，所述检测器具有输出; 以及耦合到所述检测器的时间延迟积分系统，用于通过在所述检测器的输出读取所述至少一个电荷之前积累所述至少一个电荷来实现所述至少一个电荷的时间延迟积分。 各种实施例提供具有多陷波滤波器的装置。 各种实施例提供固态激光器，微线激光器或有机发光二极管作为照射源。

公开(公告)号：US20070053186A1

公开(公告)日：2007-03-08

申请号：US11356875

申请日：2006-02-16

Applicant: Richard Reel ,  Eric Nordman ,  Tomoyuki Sakai ,  Satoshi Takahashi ,  Ryoji Inaba

Inventor： Richard Reel ,  Eric Nordman ,  Tomoyuki Sakai ,  Satoshi Takahashi ,  Ryoji Inaba

IPC: F21S6/00

CPC classification number: G01N21/64 ,  F21V5/00 ,  G01N21/645 ,  G01N27/44721 ,  G01N2021/6463 ,  G01N2201/068 ,  Y10T436/143333

Abstract: System and method for fluorescent light excitation and detection from samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light.

Abstract translation: 用于荧光灯激发和检测样品的系统和方法，以提高数值孔径和/或减少荧光灯的串扰。

公开(公告)号：US20060098039A1

公开(公告)日：2006-05-11

申请号：US10983831

申请日：2004-11-08

Applicant: Xuan-Chao Huang ,  Brant Nystrom ,  Richard Reel ,  Jamee Holiway

Inventor： Xuan-Chao Huang ,  Brant Nystrom ,  Richard Reel ,  Jamee Holiway

IPC: B41J29/393

CPC classification number: G03G15/104 ,  B41J2/2107 ,  G03G15/0121

Abstract: A method of selecting inks for use in imaging with an imaging apparatus includes determining a maximum usage of a diluted ink for use in conjunction with a saturated ink based on visual perception characteristics relating to a combination of the diluted ink and the saturated ink; generating an initial colorant space based on the maximum usage of the diluted ink, the initial colorant space expressing an initial usage of the diluted ink and an initial usage of the saturated ink at each point in the initial colorant space; optimizing the initial usage of the diluted ink and the initial usage of the saturated ink in the initial colorant space to generate a final usage of the diluted ink and a final usage of the saturated ink in a final colorant space; and generating a color conversion lookup table based on the final colorant space.

Abstract translation: 选择用于成像设备成像的墨水的方法包括基于与稀释墨水和饱和墨水的组合相关的视觉感知特性来确定与饱和墨水一起使用的稀释墨水的最大使用量; 基于稀释油墨的最大使用量产生初始着色剂空间，表示初始使用稀释油墨的初始着色剂空间和初始着色剂空间中每个点的饱和油墨的初始使用; 优化稀释油墨的初始使用和初始着色剂空间中饱和油墨的初始使用，以产生稀释油墨的最终用途，以及饱和油墨在最终着色剂空间中的最终用途; 以及基于最终着色剂空间生成颜色转换查找表。

公开(公告)号：US20050270527A1

公开(公告)日：2005-12-08

申请号：US11193853

申请日：2005-07-29

Applicant: Richard Reel

Inventor： Richard Reel

IPC: G01N21/64 ,  G01J3/04 ,  G01J3/28 ,  G01N21/03 ,  G01N21/05 ,  G01N21/27 ,  G01N21/31 ,  G01N27/447

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0262 ,  G01J3/0294 ,  G01J3/04 ,  G01J3/2803 ,  G01N21/05 ,  G01N21/31 ,  G01N27/44721 ,  G01N2021/0346

Abstract: An optical system for analyzing light from a plurality of samples is provided. The optical system includes a plurality of holders adapted to have samples located therein, a collection lens, a transmission grating, and a reimaging lens. The collection lens is configured to receive and substantially collimate light from the samples. The transmission grating is configured to spectrally disperse the substantially collimated light from the collection lens. The reimaging lens is configured to receive the light from the light dispersing element and direct the light onto a light detection device. A method of optically analyzing at least one sample is also provided.

公开(公告)号：US20050213093A1

公开(公告)日：2005-09-29

申请号：US11012664

申请日：2004-12-15

Applicant: Eric Nordman ,  Richard Reel ,  John Shigeura

Inventor： Eric Nordman ,  Richard Reel ,  John Shigeura

IPC: G01N21/64 ,  G01N27/447 ,  G01N21/00

CPC classification number: G01N27/44721

Abstract: An apparatus for detecting analytes in a sample is provided. The apparatus includes: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the detection zone with non-coherent radiation; a detector array disposed for collecting light signals emitted from markers in the detection zone excited by the radiation, the detector array having an output; and a system coupled to the detector array for effecting time delay integration of the charges on the detector array corresponding to the light signals by accumulating the charges before reading the charges at the output of the detector array. Other apparatus and methods for detecting analytes in a sample are also provided.

Abstract translation: 提供了一种用于检测样品中分析物的装置。 该装置包括：具有检测区域的一个或多个通道; 设置用于以非相干辐射照射检测区域的一个或多个照射源; 检测器阵列，被设置用于收集由所述辐射激发的所述检测区域中的标记物发出的光信号，所述检测器阵列具有输出; 以及耦合到检测器阵列的系统，用于通过在读取检测器阵列的输出端的电荷之前累积电荷来实现对与光信号对应的检测器阵列上的电荷的时间延迟积分。 还提供了用于检测样品中分析物的其它装置和方法。

公开(公告)号：US20050073731A1

公开(公告)日：2005-04-07

申请号：US10678993

申请日：2003-10-03

Applicant: Anna Deer ,  Xuan Chao Huang ,  Brant Nystrom ,  Richard Reel

Inventor： Anna Deer ,  Xuan Chao Huang ,  Brant Nystrom ,  Richard Reel

IPC: G03F3/08 ,  G06F15/00 ,  H04N1/60

CPC classification number: H04N1/6033

Abstract: A method for correcting color shift in an imaging system, including an imaging object, and a standard color conversion lookup table associated with the imaging object, includes measuring a plurality of test patches to obtain color data associated with the imaging object. A signature color data lookup table is generated, based on the color data, and is combined with the standard color conversion lookup table to generate a composite color conversion lookup table for use with the imaging object.

Abstract translation: 一种用于校正包括成像对象在内的成像系统中的颜色偏移的方法以及与成像对象相关联的标准颜色转换查找表，包括测量多个测试片以获得与成像对象相关联的颜色数据。 基于颜色数据生成签名颜色数据查找表，并与标准颜色转换查找表组合以生成与成像对象一起使用的复合颜色转换查找表。