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    MICROVALVE HAVING A REDUCED SIZE AND IMPROVED ELECTRICAL PERFORMANCE
    34.
    发明申请
    MICROVALVE HAVING A REDUCED SIZE AND IMPROVED ELECTRICAL PERFORMANCE 有权
    具有减小尺寸和改进的电气性能的微型

    公开(公告)号：US20160053916A1

    公开(公告)日：2016-02-25

    申请号：US14713332

    申请日：2015-05-15

    Applicant: DunAn Microstaq, Inc.

    Inventor： Parthiban Arunasalam ,  Chen Yang ,  E. Nelson Fuller ,  Joe A. Ojeda, SR. ,  Gengxun Kara Gurley

    IPC: F16K99/00 ,  B81B7/00

    CPC classification number: B81B7/0061 ,  B81B2201/054 ,  B81B2203/0307 ,  B81B2203/0315 ,  F16K99/0011 ,  F16K99/0028 ,  F16K99/0044 ,  F16K2099/008

    Abstract: A plate is adapted for use in a microvalve and includes a displaceable member configured for movement between a closed position, wherein the displaceable member prevents fluid communication through the microvalve, and an opened position, wherein the displaceable member does not prevent fluid communication through the microvalve. The displaceable member includes an elongated arm portion, a plurality of actuator ribs connected through a central spine to the elongated arm portion, and a hinge portion. The actuator ribs have a first portion and a second portion, the first portion having a first end and a second end, the second end of the first portion connected to the central spine, the second portion having a first end and a second end, the second end of the second portion connected to the central spine. A channel is formed in the plate. A plurality of elongated openings are formed in the plate and define the actuator ribs, each elongated opening having longitudinally extending side edges. One of the elongated openings separates each rib in the second portion of ribs from an adjacent rib or the plate. The channel and a longitudinally extending side edge of one of the elongated openings separate the second portion of the actuator ribs from the plate and define an electrical isolation region.

    Abstract translation: 板适于用于微型阀，并且包括可移位构件，其构造成在关闭位置之间移动，其中可移位构件防止通过微型阀的流体连通和打开位置，其中可移位构件不阻止流体通过微型阀连通 。 可移动构件包括细长的臂部分，通过中心脊连接到细长臂部分的多个致动器肋和铰链部分。 致动器肋具有第一部分和第二部分，第一部分具有第一端和第二端，第一部分的第二端连接到中心脊，第二部分具有第一端和第二端， 第二部分的第二端连接到中心脊。 在板中形成通道。 多个细长的开口形成在板中并限定致动器肋，每个细长的开口具有纵向延伸的侧边缘。 一个细长的开口将肋的第二部分中的每个肋与相邻的肋或板分开。 一个细长开口的通道和纵向延伸的侧边缘将致动器肋的第二部分与板分隔开并限定电隔离区。

    BUBBLE-FREE MICROFLUIDIC VALVE SYSTEMS AND METHODS
    37.
    发明申请
    BUBBLE-FREE MICROFLUIDIC VALVE SYSTEMS AND METHODS 有权
    无爆炸微流体阀系统和方法

    公开(公告)号：US20150150720A1

    公开(公告)日：2015-06-04

    申请号：US14618102

    申请日：2015-02-10

    Applicant: NOVARTIS AG

    Inventor： Nicholas Max Gunn ,  Andrew David Johnson

    IPC: A61F9/007

    CPC classification number: A61F9/00781 ,  A61F9/0017 ,  A61F2250/0003 ,  A61M2205/0244 ,  A61M2210/0612 ,  B81B2201/054 ,  B81B2203/0127 ,  F16K99/0015 ,  F16K99/0057 ,  F16K2099/0088 ,  Y10T137/7895

    Abstract: A microfluidic valve for implantation in an eye of a patient is disclosed. The valve may include a chamber formed between a substrate and a flexible membrane. The valve may also include a boss disposed in the chamber and having a top edge in selective contact with the flexible membrane. The top edge includes a relief portion and a non-relief portion, with the relief portion being structurally arranged so that a pressure required to separate the membrane from the relief portion is less than a pressure required to separate the membrane from the non-relief portion. The valve also may include an inlet extending through the boss and the substrate through which fluid enters the chamber and an outlet configured to allow fluid to exit the chamber. Methods for priming a microfluidic valve are also disclosed.

    Abstract translation: 公开了一种用于植入患者眼睛的微流体阀。 阀可以包括形成在基底和柔性膜之间的腔室。 阀还可以包括设置在腔室中并具有与柔性膜选择性接触的顶边缘的凸台。 顶部边缘包括一个浮雕部分和一个非浮雕部分，其中该浮雕部分在结构上被布置成使得隔离该浮雕部分所需的压力小于将膜与该非浮雕部分分开所需的压力 。 阀还可以包括延伸穿过凸台和基底的入口，流体通过该基底进入腔室，以及出口，其构造成允许流体离开腔室。 还公开了引发微流控阀的方法。

    METHOD OF MAKING A MICROFLUIDIC DEVICE
    39.
    发明申请
    METHOD OF MAKING A MICROFLUIDIC DEVICE 有权
    制造微流体装置的方法

    公开(公告)号：US20130034467A1

    公开(公告)日：2013-02-07

    申请号：US13196421

    申请日：2011-08-02

    Applicant: Robert Johnstone ,  Stephane Martel

    Inventor： Robert Johnstone ,  Stephane Martel

    IPC: B01L3/00 ,  B32B9/04 ,  B32B9/00 ,  C23F1/02 ,  H01L21/31

    CPC classification number: B81C1/00182 ,  B81B2201/054 ,  B81C2201/019 ,  B81C2203/0735

    Abstract: A microfabricated device is fabricated by depositing a first metal layer on a substrate to provide a first electrode of an electrostatic actuator, depositing a first structural polymer layer over the first metal layer, depositing a second metal layer over said first structural polymer layer to form a second electrode of the electrostatic actuator, depositing an insulating layer over said first structural polymer layer, planarizing the insulating layer, etching the first structural polymer layer through the insulating layer and the second metal layer to undercut the second metal layer, providing additional pre-formed structural polymer layers, at least one of which has been previously patterned, and finally bonding the additional structural layers in the form of a stack over the planarized second insulating layer to one or more microfluidic channels. The technique can also be used to make cross over channels in devices without electrostatic actuators, in which case the metal layers can be omitted.

    Abstract translation: 通过在衬底上沉积第一金属层以提供静电致动器的第一电极，在第一金属层上方沉积第一结构聚合物层，在第一结构聚合物层上沉积第二金属层以形成微结构聚合物层 静电致动器的第二电极，在所述第一结构聚合物层上沉积绝缘层，平坦化绝缘层，通过绝缘层和第二金属层蚀刻第一结构聚合物层以切割第二金属层，从而提供额外的预成形 结构聚合物层，其中至少一个已经被预先图案化，并且最后将平坦化的第二绝缘层上的堆叠形式的附加结构层结合到一个或多个微流体通道。 该技术也可以用于在没有静电致动器的装置中跨越通道，在这种情况下可以省略金属层。

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