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公开(公告)号：US09989773B2
公开(公告)日：2018-06-05
申请号：US15083357
申请日：2016-03-29
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： Frederick Allen Moore
IPC: G02B13/16 , G02B27/10 , G02B13/04 , G02B13/22 , G02B27/14 , H04N5/225 , H04N9/09 , H04N9/04 , H04N9/097 , H04N9/07
CPC classification number: G02B27/1013 , G02B13/04 , G02B13/22 , G02B27/141 , H04N5/2254 , H04N5/2258 , H04N9/045 , H04N9/09 , H04N9/097
Abstract: An optical system for use with a multi-channel wide field imaging system, the optical system including an objective lens, a dichroic element to split light into a first wavelength range and a second wavelength range, the dichroic element positioned to receive near parallel chief rays from the objective lens, a first channel lens system to receive light of the first wavelength range from the dichroic element; and a second channel lens system to receive light of the second wavelength range from the dichroic element.
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公开(公告)号：US09918619B2
公开(公告)日：2018-03-20
申请号：US14278833
申请日：2014-05-15
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： John Tesar
CPC classification number: A61B1/002 , G02B23/2446
Abstract: A highly corrected relay system for medical endoscopes or the like is provided. The system includes a plurality of bonded lenses that are selected to provide color correction from the blue region of the spectrum through to the near infrared region of the spectrum. The system allows co-located visible and near infrared images to be resolved on a single detector.
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43.发明申请公开(公告)号：US20180028079A1
公开(公告)日：2018-02-01
申请号：US15663290
申请日：2017-07-28
Applicant: Novadaq Technologies Inc.
Inventor： Lina GUREVICH , Lori Ann SWALM
CPC classification number: A61B5/0275 , A61B5/0261 , A61B5/7232 , A61B5/7267 , A61B5/743 , A61B2576/00 , G06K9/6218 , G06K9/6219 , G06K9/6223 , G06K9/6274 , G06K9/66 , G06K2209/05 , G06T7/0012 , G06T7/557 , G06T2207/10024 , G06T2207/10064 , G06T2207/10081 , G06T2207/10104 , G06T2207/30024 , G06T2207/30104
Abstract: Methods and systems for characterizing tissue of a subject include acquiring and receiving data for a plurality of time series of fluorescence images, identifying one or more attributes of the data relevant to a clinical characterization of the tissue, and categorizing the data into clusters based on the attributes such that the data in the same cluster are more similar to each other than the data in different clusters, wherein the clusters characterize the tissue. The methods and systems further include receiving data for a subject time series of fluorescence images, associating a respective cluster with each of a plurality of subregions in the subject time series of fluorescence images, and generating a subject spatial map based on the clusters for the plurality of subregions in the subject time series of fluorescence images. The generated spatial maps may then be used as input for tissue diagnostics using supervised machine learning.
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公开(公告)号：US20180020933A1
公开(公告)日：2018-01-25
申请号：US15476290
申请日：2017-03-31
Applicant: Novadaq Technologies Inc.
Inventor： Peter DVORSKY , David Mark Henri GOYETTE , T. Bruce FERGUSON, JR. , Cheng CHEN
IPC: A61B5/0275 , G06T7/00 , A61B6/00 , A61B5/026 , G06T7/246 , A61M5/00 , G06T7/12 , G06T7/90 , A61B5/00
CPC classification number: A61B5/0275 , A61B5/0059 , A61B5/0261 , A61B5/489 , A61B5/7225 , A61B6/503 , A61B6/504 , A61B6/507 , A61B2576/02 , A61M5/007 , G06T7/0012 , G06T7/12 , G06T7/248 , G06T7/90 , G06T2207/10064 , G06T2207/30104
Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.
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45.发明申请公开(公告)号：US20170354392A1
公开(公告)日：2017-12-14
申请号：US15623100
申请日：2017-06-14
Applicant: Novadaq Technologies Inc.
Inventor： John J.P. FENGLER , Paul Roald WESTWICK , Frederick Allen MOORE
CPC classification number: A61B6/5205 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/045 , A61B1/05 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/0684 , A61B1/07 , A61B1/3132 , A61B5/0071 , A61B5/1121 , A61B5/6869 , A61B5/6875 , A61B5/7221 , A61B5/7264 , A61B6/481 , A61B2505/05 , A61B2562/0219 , A61B2562/0233 , A61B2576/00 , G02B23/12 , G06F19/321 , G06T5/001 , G06T5/50 , G06T2207/10064 , G06T2207/10068 , G06T2207/20008 , G06T2207/30004 , H04N5/23232 , H04N5/235 , H04N5/2354 , H04N5/332 , H04N2005/2255
Abstract: Adaptive imaging methods and systems for generating enhanced low light video of an object for medical visualization are disclosed and include acquiring, with an image acquisition assembly, a sequence of reference frames and/or a sequence of low light video frames depicting the object, assessing relative movement between the image acquisition assembly and the object based on at least a portion of the acquired sequence of reference video frames or the acquired sequence of low light video frames, adjusting a level of image processing of the low light video frames based at least in part on the relative movement between the image acquisition assembly and the object, and generating a characteristic low light video output from a quantity of the low light video frames, wherein the quantity of the low light video frames is based on the adjusted level of image processing of the low light video frames.
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Patent Agency Ranking
公开(公告)号：US20170209050A1
公开(公告)日：2017-07-27
申请号：US15416876
申请日：2017-01-26
Applicant: Novadaq Technologies Inc.
Inventor： John Josef Paul FENGLER , Robert Anthony STEAD
CPC classification number: A61B5/0071 , A61B1/00186 , A61B1/043 , A61B1/051 , A61B1/0638 , A61B1/0684 , A61B5/0035 , A61B5/0084 , G01J1/00 , G01J1/58 , G01J3/0205 , G01J3/0208 , G01J3/021 , G01J3/0248 , G01J3/10 , G01J3/36 , G01J3/4406 , G02B21/16 , G02B27/1013 , H04N5/2256 , H04N5/23245 , H04N5/2354 , H04N5/238 , H04N5/332 , H04N9/045 , H04N9/097 , H04N13/204 , H04N2209/049
Abstract: A fluorescence imaging system for imaging an object, the system includes a white light provider that emits white light, an excitation light provider that emits excitation light in a plurality of excitation wavebands for causing the object to emit fluorescent light, a component that directs the white light and excitation light to the object and collects reflected white light and emitted fluorescent light from the object, a filter that blocks light in the excitation wavebands and transmits at least a portion of the reflected white light and fluorescent light, and an image sensor assembly that receives the transmitted reflected white light and the fluorescent light.
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公开(公告)号：US20170142314A1
公开(公告)日：2017-05-18
申请号：US15348664
申请日：2016-11-10
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： Frederick Allen Moore , Anton Walter LAMPRECHT , Lesley Myron OTSIG , Paul Roald WESTWICK , Muhammad Nasir al-Din bin ZULKAFLY , Gavin Michael MURRAY , Adam John TYNAN , James Elliott CAMERON , Gregory Vincent BROWNE , Isabelle FONTAINE
CPC classification number: H04N5/2354 , A61B46/10 , A61B90/30 , A61B90/361 , A61B2017/00477 , A61B2090/306 , A61B2090/309 , A61B2090/3941 , H04N5/2252 , H04N5/2256 , H04N5/2351
Abstract: An imaging device may include a first illumination port to output first light having a first illumination distribution at a target to illuminate the target, a second illumination port to output second light having a second illumination distribution at the target to illuminate the target, the second illumination distribution being substantially similar to the first illumination distribution at the target, the second illumination port being spaced apart from the first illumination port, the first and second illumination distributions being simultaneously provided to the target and overlapping at the target. The illumination from the first and second ports may be matched to a same aspect ratio and field of view coverage as the imaging field of view.
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48.发明申请POLARIZATION DEPENDENT FILTER, SYSTEM USING THE SAME, AND ASSOCIATED KITS AND METHODS 审中-公开偏振相关滤光片，使用该滤光片的系统及相关工具及方法公开(公告)号：US20170059878A1
公开(公告)日：2017-03-02
申请号：US15251154
申请日：2016-08-30
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： Frederick Allen MOORE
CPC classification number: G02B5/3083 , G02B5/3058 , G02B23/2446 , G02B27/0025
Abstract: A system includes a birefringent lens, and a polarization filter that transmits light of a first polarization output from the birefringent lens in a first direction and filters out light of a second polarization output from the birefringent lens along the first direction.
Abstract translation: 一种系统包括双折射透镜和偏振滤光器，该偏振滤光器沿第一方向透射从双折射透镜输出的第一偏振光，并滤出沿着第一方向从双折射透镜输出的第二偏振光。
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49.发明申请公开(公告)号：US20160291332A1
公开(公告)日：2016-10-06
申请号：US15083357
申请日：2016-03-29
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： Frederick Allen MOORE
CPC classification number: G02B27/1013 , G02B13/04 , G02B13/22 , G02B27/141 , H04N5/2254 , H04N5/2258 , H04N9/045 , H04N9/09 , H04N9/097
Abstract: An optical system for use with a multi-channel wide field imaging system, the optical system including an objective lens, a dichroic element to split light into a first wavelength range and a second wavelength range, the dichroic element positioned to receive near parallel chief rays from the objective lens, a first channel lens system to receive light of the first wavelength range from the dichroic element; and a second channel lens system to receive light of the second wavelength range from the dichroic element.
Abstract translation: 一种用于多通道宽场成像系统的光学系统，所述光学系统包括物镜，将光分成第一波长范围和第二波长范围的二向色元件，所述二向色元件定位成接收近平行的主射线 来自所述物镜的第一透镜系统，用于从所述二向色元件接收第一波长范围的光; 以及第二透镜系统，用于从二向色元件接收第二波长范围的光。
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50.发明申请IMAGING A TARGET FLUOROPHORE IN A BIOLOGICAL MATERIAL IN THE PRESENCE OF AUTOFLUORESCENCE 有权在自动化存在下在生物材料中成像目标荧光公开(公告)号：US20160110870A1
公开(公告)日：2016-04-21
申请号：US14868369
申请日：2015-09-28
Applicant: NOVADAQ TECHNOLOGIES INC.
Inventor： Eduardo Hiroyuki MORIYAMA , Chun Ho SZE
CPC classification number: G01N21/6456 , A61B1/043 , A61B1/0638 , A61B5/0071 , A61B5/7203 , G01N21/6408 , G01N21/6428 , G01N21/6458 , G01N21/6486 , G01N2021/6419 , G01N2021/6439 , G06T5/50 , G06T7/0016 , G06T2207/10064 , G06T2207/10152 , G06T2207/20224 , G06T2207/30024
Abstract: Methods and systems are disclosed for extracting an image of a target fluorophore in a biological material, which involve inducing both autofluorescence of the biological material and fluorescence of the fluorophore, acquiring an image arising from both the autofluorescence of the biological material and the fluorophore, and an image arising only from the autofluorescence, subtracting the two images to produce an image representing only the fluorophore, wherein relative intensities of the excitation light used to induce the autofluorescence and the fluorescence are modulated prior to acquiring the images.
Abstract translation: 公开了用于提取生物材料中的目标荧光团的图像的方法和系统，其涉及诱导生物材料的自发荧光和荧光团的荧光，获取由生物材料和荧光团的自发荧光引起的图像，以及 仅从自发荧光产生的图像，减去两个图像以产生仅表示荧光团的图像，其中用于诱导自发荧光的激发光的相对强度和荧光在获取图像之前被调制。
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