公开(公告)号：US20130213261A1

公开(公告)日：2013-08-22

申请号：US13731747

申请日：2012-12-31

Applicant: MITSUBISHI MATERIALS CORPORATION

Inventor： Shinji Otani ,  Yoshifumi Yamamoto ,  Takashi Yamaji

IPC: C08L1/28 ,  B22F1/00

CPC classification number: C08L1/28 ,  B22F1/0003 ,  B22F1/0074 ,  B22F9/082 ,  B22F2009/0828 ,  B22F2301/255

Abstract: A silver powder for silver clay, wherein a main component is Ag, and an amount of P is controlled to be 100 ppm or less.

Abstract translation: 用于银粘土的银粉，其中主要成分为Ag，P的量控制在100ppm以下。

公开(公告)号：US20130071590A1

公开(公告)日：2013-03-21

申请号：US13674307

申请日：2012-11-12

Applicant: Arizona Board of Regents, a body corporate acting

Inventor： Nicole Herbots ,  James Doug Bradley ,  Murdock Hart ,  David Sell ,  Shawn D. Whaley ,  Qian Xing Bradley

IPC: H01B1/12 ,  A61F2/16 ,  B65D25/08

CPC classification number: H01B1/122 ,  A61L27/34 ,  A61L27/50 ,  A61L27/52 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2430/16 ,  B65D25/08 ,  C08L1/28 ,  C09D101/28 ,  Y10T428/1352 ,  Y10T428/139 ,  Y10T428/31507 ,  Y10T428/31663 ,  Y10T428/3188 ,  Y10T428/31971

Abstract: Compositions are disclosed containing a solvated viscoelastic polymeric gel diluted into an ionically conductive aqueous solution which can be usefully applied to any surface that is hydrophobic to act, for example, as an antifogging coating with minimal optical distortion and excellent transparency. The compositions can also be used as lubricious agents on medical implants, shunts, and surgical supplies to minimize tissue trauma, to maximize bio-compatibility, and to increase healing by enhancing better irrigation and flow in adjacent tissue.

Abstract translation: 公开了包含稀释成离子导电水溶液的溶剂化粘弹性聚合物凝胶的组合物，其可有效地施加到任何疏水性表面上，例如作为具有最小光学变形和优异透明度的防雾涂层。 组合物还可以用作医疗植入物，分流器和手术用品上的润滑剂，以最小化组织创伤，最大化生物相容性，并通过增强相邻组织中更好的灌注和流动来增加愈合。

公开(公告)号：US20130004460A1

公开(公告)日：2013-01-03

申请号：US13574970

申请日：2011-01-25

Applicant: Pierre Weiss ,  Jerome Guicheux ,  Gildas Rethore ,  Emile Rederstorff ,  Samia Laib

Inventor： Pierre Weiss ,  Jerome Guicheux ,  Gildas Rethore ,  Emile Rederstorff ,  Samia Laib

IPC: A61K35/00 ,  A61K38/16 ,  A61K31/7088 ,  A61K31/732 ,  A61K31/722 ,  A61K31/728 ,  A61K31/70 ,  A61K38/39 ,  A61K38/17 ,  A61K38/07 ,  A61K31/715 ,  A61K31/717 ,  A61P19/04 ,  A61P19/08 ,  A61P9/00 ,  A61P17/00 ,  A61K38/02

CPC classification number: G01N33/54353 ,  A61K9/06 ,  A61K47/36 ,  C07F7/1804 ,  C08B15/05 ,  C08B37/003 ,  C08B37/0045 ,  C08B37/0072 ,  C08G18/10 ,  C08G18/12 ,  C08G18/6446 ,  C08G18/718 ,  C08G2210/00 ,  C08H1/00 ,  C08H1/06 ,  C08J3/075 ,  C08J3/246 ,  C08J2300/108 ,  C08J2305/06 ,  C08J2305/08 ,  C08L1/08 ,  C08L1/28 ,  C08L5/06 ,  C08L5/08 ,  C08L89/00 ,  C08L89/06 ,  C08L2203/02 ,  C08G18/3275 ,  C08L2666/26

Abstract: The invention concerns: a silylated biomolecule having the following formula (I): the process for the preparation of a silylated biomolecule of formula (I), the use of a silylated biomolecule of formula (I) to functionalize the surface of a support, a process for the preparation of a hydrogel by use of a silylated biomolecule of formula (I), the hydrogel obtainable by said process, said hydrogel as a biological tissue substitute, a composition comprising said hydrogel in a pharmaceutically acceptable vehicle, said composition for the release of active principle.

Abstract translation: 本发明涉及：具有下式（I）的甲硅烷基化生物分子：制备式（I）的甲硅烷基化生物分子的方法，使用式（I）的甲硅烷基化生物分子将载体的表面官能化， 用于通过使用式（I）的甲硅烷基化生物分子制备水凝胶的方法，可通过所述方法获得的水凝胶，所述水凝胶作为生物组织替代物，在药学上可接受的载体中包含所述水凝胶的组合物，所述用于释放的组合物 的积极原则。

公开(公告)号：US08187626B2

公开(公告)日：2012-05-29

申请号：US12779108

申请日：2010-05-13

Applicant: Kelman I. Cohen ,  Yousef Mohajer

Inventor： Kelman I. Cohen ,  Yousef Mohajer

IPC: A61F13/00

CPC classification number: A61L15/44 ,  A61K31/715 ,  A61K31/734 ,  A61K33/34 ,  A61K33/38 ,  A61L15/28 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/232 ,  A61L2300/606 ,  A61K2300/00 ,  C08L1/28

Abstract: Transition metal (e.g., silver and copper) derivatized phosphorylated polysaccharides (cellulose, starch, gauze) provide antimicrobial and elastase sequestration properties to wound dressings, and the wound dressing have enhanced water sorption and elastase sequestration when used with alginates. Wound dressings with alginates (e.g., silver alginate, crosslinked alginates, etc.) provide enhanced wound fluid absorption as well as elastase sequestration.

Abstract translation: 过渡金属（例如银和铜）衍生的磷酸化多糖（纤维素，淀粉，纱布）为伤口敷料提供抗菌和弹性蛋白酶螯合特性，并且当与藻酸盐一起使用时，伤口敷料具有增强的水吸附和弹性蛋白酶螯合。 具有藻酸盐（例如藻酸银，交联藻酸盐等）的伤口敷料提供增强的伤口液吸收以及弹性蛋白酶螯合。

公开(公告)号：US20120073469A1

公开(公告)日：2012-03-29

申请号：US13251574

申请日：2011-10-03

Applicant: John F. Hatton ,  Benjamin S. Ber ,  Gregory P. Stewart

Inventor： John F. Hatton ,  Benjamin S. Ber ,  Gregory P. Stewart

IPC: A61K6/097

CPC classification number: A61K6/097 ,  A61C5/40 ,  A61K6/0038 ,  A61K6/0041 ,  A61K6/0606 ,  A61K6/0625 ,  C08L1/28

Abstract: The invention is directed to an improved dental composition useful in the repair of cavities, apex repairs, root perforations and root canals. Disclosed is a dental composition and dental composition additive which have improved handling characteristics, for example improved viscosity and setting time. The addition of effective amounts of a modified cellulose and calcium chloride to available dental repair compounds, such as mineral trioxide compound, results in the improved dental composition without affecting the other characteristics of the dental repair compound.

Abstract translation: 本发明涉及一种用于修复腔，顶端修复，根部穿孔和根管的改进的牙齿组合物。 公开了具有改善的处理特性的牙科用组合物和牙科组合物添加剂，例如改进的粘度和凝固时间。 将有效量的改性纤维素和氯化钙添加到可用的牙齿修复化合物，例如三氧化二砷化合物中，导致改进的牙科组合物，而不影响牙齿修复化合物的其它特征。

公开(公告)号：US20110223214A1

公开(公告)日：2011-09-15

申请号：US13127331

申请日：2009-11-27

Applicant: Lars Åke Malmsten ,  Niklas Axén ,  Hans Lennernäs ,  Anders Carlsson

Inventor： Lars Åke Malmsten ,  Niklas Axén ,  Hans Lennernäs ,  Anders Carlsson

IPC: A61K9/14 ,  A61K31/167 ,  A61K31/57 ,  A61K31/277 ,  A61P35/00 ,  A61P29/00 ,  A61P5/28

CPC classification number: A61K31/167 ,  A61K9/0019 ,  A61K31/57 ,  A61K47/02 ,  A61K47/38 ,  A61L27/446 ,  A61L27/58 ,  A61L2400/06 ,  C08L1/28

Abstract: Carboxymethylcellulose, notably sodium carboxymethylcellulose or other alkali metal or alkaline earth metal salts of carboxymethylcellulose, are employed to control solidification time of compositions comprising one or more bioresorbable ceramics, notably a hydratable calcium sulphate, in order to facilitate preparation of a ready-to-use composition for inserting into the body by injection.

Abstract translation: 使用羧甲基纤维素，特别是羧甲基纤维素钠或羧甲基纤维素的其它碱金属或碱土金属盐来控制包含一种或多种生物可再吸收陶瓷，特别是可水合硫酸钙的组合物的固化时间，以便于制备即用型 用于通过注射插入体内的组合物。

公开(公告)号：US20110201117A1

公开(公告)日：2011-08-18

申请号：US12809534

申请日：2008-12-18

Applicant: Zhilian Yue ,  Feng Wen ,  Hanry Yu

Inventor： Zhilian Yue ,  Feng Wen ,  Hanry Yu

IPC: C12N5/071

CPC classification number: B32B3/26 ,  A61L27/20 ,  A61L27/56 ,  C08B11/20 ,  C08J9/28 ,  C08J2201/024 ,  C08J2201/026 ,  C08J2201/0484 ,  C08J2201/0524 ,  C08J2205/044 ,  C08J2207/10 ,  C08J2301/28 ,  C08L1/14 ,  Y10T428/249921 ,  Y10T428/249978 ,  Y10T428/249979 ,  C08L1/28

Abstract: Scaffold comprises a polymer defining macropores and comprising hydroxypropylcellulose partially substituted by a substituent comprising a self-crosslinkable group, which is crosslinked through the self-crosslinkable group. The macropores have an average pore size larger than 50 microns and are at least partially interconnected. In one method, bicontinuous emulsion comprising a continuous aqueous phase and a continuous polymer phase is formed. The polymer phase comprises hydroxypropylcellulose partially substituted by a substituent comprising a self-crosslinkable group, and is crosslinked through the self-crosslinkable group to form a polymer defining at least partially interconnected pores. In another method, phase separation is induced in a solution comprising a polymer precursor and water to form a bicontinuous emulsion comprising a continuous polymer phase and a continuous aqueous phase. The polymer precursor comprises a self-crosslinkable group and is crosslinked through the self-crosslinkable group in the emulsion to form a polymer defining at least partially interconnected macropores.

公开(公告)号：US20110159272A1

公开(公告)日：2011-06-30

申请号：US12824105

申请日：2010-06-25

Applicant: Zhilian Yue ,  Feng Wen ,  Hanry Yu

Inventor： Zhilian Yue ,  Feng Wen ,  Hanry Yu

IPC: B32B3/26 ,  C08B15/10

CPC classification number: B32B3/26 ,  A61L27/20 ,  A61L27/56 ,  C08B11/20 ,  C08J9/28 ,  C08J2201/024 ,  C08J2201/026 ,  C08J2201/0484 ,  C08J2201/0524 ,  C08J2205/044 ,  C08J2207/10 ,  C08J2301/28 ,  C08L1/14 ,  Y10T428/249921 ,  Y10T428/249978 ,  Y10T428/249979 ,  C08L1/28

Abstract: Scaffold comprises a polymer defining macropores and comprising hydroxypropylcellulose partially substituted by a substituent comprising a self-crosslinkable group, which is crosslinked through the self-crosslinkable group. The macropores have an average pore size larger than 50 microns and are at least partially interconnected. In one method, bicontinuous emulsion comprising a continuous aqueous phase and a continuous polymer phase is formed. The polymer phase comprises hydroxypropylcellulose partially substituted by a substituent comprising a self-crosslinkable group, and is crosslinked through the self-crosslinkable group to form a polymer defining at least partially interconnected pores. In another method, phase separation is induced in a solution comprising a polymer precursor and water to form a bicontinuous emulsion comprising a continuous polymer phase and a continuous aqueous phase. The polymer precursor comprises a self-crosslinkable group and is crosslinked through the self-crosslinkable group in the emulsion to form a polymer defining at least partially interconnected macropores.

Abstract translation: 脚手架包含限定大孔的聚合物，并且包含部分由包含自交联基团的取代基取代的羟丙基纤维素，所述取代基通过自交联基团交联。 大孔具有大于50微米的平均孔径并且至少部分互连。 在一种方法中，形成包含连续水相和连续聚合物相的双连续乳液。 聚合物相包含部分由包含自交联基团的取代基取代的羟丙基纤维素，并且通过自交联基团交联以形成限定至少部分互连的孔的聚合物。 在另一种方法中，在包含聚合物前体和水的溶液中诱导相分离以形成包含连续聚合物相和连续水相的双连续乳液。 聚合物前体包含自交联基团，并且通过乳液中的自交联基团交联以形成限定至少部分互连的大孔的聚合物。

公开(公告)号：US07964062B2

公开(公告)日：2011-06-21

申请号：US11254812

申请日：2005-10-21

Applicant: Kenji Yamamoto ,  Masahiko Ogawa

Inventor： Kenji Yamamoto ,  Masahiko Ogawa

IPC: D21H19/00 ,  C08L83/04 ,  C08L83/05 ,  C08L83/06 ,  C08L83/07

CPC classification number: C08L1/10 ,  C08G77/12 ,  C08G77/20 ,  C08L1/26 ,  C08L1/28 ,  C08L83/04 ,  D21H19/40 ,  D21H19/52 ,  C08L83/00 ,  C08L2666/26

Abstract: A paper treating agent comprising 100 parts by mass of organopolysiloxane (A), from 100 to 100,000 parts by mass of water (E), and 0.1 to 100 parts by mass of a surfactant (F), characterized in that the agent further comprises 50 to 1,000 parts by mass of a cellulosic resin (C), wherein 0.5 to 2.5 hydroxyl groups per glucose unit of said cellulosic resin are etherized or esterified, and a viscosity of an aqueous 2% solution of said cellulosic resin is from 2 to 100 mPa·s.

Abstract translation: 一种纸处理剂，其包含100质量份有机聚硅氧烷（A），100至100,000质量份水（E）和0.1至100质量份表面活性剂（F），其特征在于，所述试剂还包含50 至1,000质量份的纤维素树脂（C），其中所述纤维素树脂的每个葡萄糖单元的0.5至2.5个羟基被醚化或酯化，并且所述纤维素树脂的2％水溶液的粘度为2至100mPa ·s。

公开(公告)号：US20110027332A1

公开(公告)日：2011-02-03

申请号：US12086557

申请日：2006-12-15

Applicant: James J. Benedict ,  Greg Allen Brewster ,  Donald Barclay Greeman

Inventor： James J. Benedict ,  Greg Allen Brewster ,  Donald Barclay Greeman

IPC: A61F2/28 ,  A61K47/30 ,  A61K47/32 ,  A61K47/36 ,  A61K47/38 ,  A61K33/42 ,  A61K38/17 ,  A61P19/00

CPC classification number: A61L27/3608 ,  A61L27/20 ,  A61L27/28 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L2430/02 ,  C08L1/28

Abstract: A firm but pliable medical device for use as a bone graft substitute or bone graft extender retains its shape without the requirement of a containment device, such as a syringe. Because the device is solid, it is easy to locate or position in-vivo and, in the moist environment of the body, it will hold its shape well, for an extended time. Because the lyophilized pliable medical device is porous, it adsorbs blood and other beneficial cells containing body fluids, such as bone marrow, contributing to its superior bone repair efficacy in comparison to an analogous putty that has not been lyophilized. In addition these lyophilized pliable medical devices are easier to terminally steam sterilize than the analogous putty because there is no moisture present to boil and “blow-out” of the containment device (syringe). The glycerin that is present in the formulation lends pliability but has a low vapor pressure.

Abstract translation: 用作骨移植物替代物或骨移植物延长剂的牢固但柔韧的医疗装置保持其形状，而不需要诸如注射器的容纳装置。 因为该装置是固体，所以很容易在体内定位或定位，并且在身体的潮湿环境中，其将保持良好的形状，长时间。 因为冻干的柔韧的医疗装置是多孔的，因此与没有被冻干的类似的腻子相比，它吸收含有体液如骨髓的血液和其它有益细胞，有助于其优异的骨修复功效。 此外，这些冻干的柔韧的医疗设备比类似的油灰更容易终止蒸汽消毒，因为不存在水分以便将容器（注射器）煮沸和“吹出”。 存在于制剂中的甘油具有柔韧性但具有低蒸气压。