公开(公告)号：US10144760B2

公开(公告)日：2018-12-04

申请号：US15018129

申请日：2016-02-08

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Catherine A. Bothof ,  Kannan Seshadri ,  James I. Hembre ,  Robert T. Fitzsimons, Jr. ,  George W. Griesgraber ,  Yi He

IPC: C07K1/22 ,  C07K14/765 ,  C07H1/08 ,  B01D67/00 ,  B01D71/56 ,  C09D179/02

Abstract: A substrate comprising a crosslinked polymer primer layer, and grafted thereto a ligand-functionalized polymer is provided. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, and proteins, at pH's near or below the pI's of the biomaterials.

公开(公告)号：US10017461B2

公开(公告)日：2018-07-10

申请号：US15485636

申请日：2017-04-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Catherine A. Bothof ,  Yi He ,  Jerald K. Rasmussen ,  Kannan Seshadri ,  Clinton P. Waller, Jr. ,  Douglas E. Weiss

IPC: C07C279/10 ,  C07C279/12 ,  C08F259/08 ,  C08F283/04 ,  C08J7/18 ,  B01J20/285

CPC classification number: C07C279/12 ,  B01D39/1676 ,  B01J20/285 ,  C07C277/08 ,  C07C279/14 ,  C07C281/16 ,  C07K1/34 ,  C08F259/08 ,  C08F283/04 ,  C08G69/48 ,  C08J7/18 ,  C08J9/283 ,  C08J9/42 ,  C08J2327/16 ,  C08J2377/00 ,  C12N7/00 ,  Y02C10/08 ,  Y10T428/31855

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

公开(公告)号：US20170240591A1

公开(公告)日：2017-08-24

申请号：US15591490

申请日：2017-05-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Kannan Seshadri ,  Robert T. Fitzsimons, JR. ,  James I. Hembre ,  Catherine A. Bothof ,  Erin A. Satterwhite ,  George W. Griesgraber ,  Yi He ,  Louis C. Haddad

IPC: C07K1/14 ,  B01D21/01 ,  C08F126/02 ,  C08F120/60 ,  C12N11/08 ,  C08G73/02

CPC classification number: C07K1/14 ,  B01D21/01 ,  C08F120/60 ,  C08F126/02 ,  C08G69/10 ,  C08G73/0206 ,  C08G73/022 ,  C08G73/028 ,  C08L77/04 ,  C08L79/02 ,  C08L83/08 ,  C12N7/02 ,  C12N11/08 ,  G01N33/54393 ,  G01N33/545 ,  Y10T428/249978 ,  Y10T428/249991 ,  Y10T428/2935 ,  Y10T428/2998 ,  Y10T442/20

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

公开(公告)号：US20170183299A1

公开(公告)日：2017-06-29

申请号：US15459475

申请日：2017-03-15

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  George W. Griesgraber ,  James I. Hembre

IPC: C07C277/08 ,  C08F120/36 ,  B01J20/32 ,  G01N1/40 ,  B01J20/26 ,  B01J20/28 ,  C07C279/12 ,  C09D4/00

CPC classification number: C07C277/08 ,  B01J20/261 ,  B01J20/28033 ,  B01J20/327 ,  C07C277/02 ,  C07C279/12 ,  C08F26/00 ,  C08F120/36 ,  C08F126/02 ,  C08F220/36 ,  C09D4/00 ,  C09D133/14 ,  D06M14/30 ,  G01N1/405 ,  G01N33/53 ,  G01N33/545 ,  C07C279/08

Abstract: A process for preparing guanidino-functional, free radically polymerizable compounds comprises (a) combining (1) an amine compound comprising (i) at least one primary aliphatic amino group and (ii) at least one secondary aliphatic amino group, primary aromatic amino group, or secondary aromatic amino group, and (2) a guanylating agent; (b) allowing or inducing reaction of the amine compound and the guanylating agent to form a guanylated amine compound; (c) combining (1) the guanylated amine compound, and (2) a reactive monomer comprising (i) at least one ethylenically unsaturated group and (ii) at least one group that is reactive with an amino group; and (d) allowing or inducing reaction of the guanylated amine compound and the reactive monomer to form a guanidino-functional, free radically polymerizable compound.

公开(公告)号：US20170131190A1

公开(公告)日：2017-05-11

申请号：US15414265

申请日：2017-01-24

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Masayuki Nakamura ,  Naota Sugiyama ,  Cynthia D. Zook ,  Stephen E. Amos ,  Jerald K. Rasmussen ,  Nicole M. Gryska

IPC: G01N1/40 ,  B01D15/38 ,  B01J20/28 ,  C12N15/10

CPC classification number: G01N1/405 ,  B01D15/3804 ,  B01J20/28004 ,  B01J20/28021 ,  B01J20/281 ,  B01J20/289 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3261 ,  B01J20/3291 ,  B01J2220/82 ,  C07K1/16 ,  C12N15/1006 ,  C12N15/101

Abstract: A composition for use in bioseparation. The composition includes a plurality of hollow particles having a siliceous surface. The composition further includes a surface-modifying agent bonded to the hollow particles. The surface-modifying agent includes a binding segment and a reactive segment. The binding segment includes a silyl group and the reactive segment includes a reactive nitrogen group.

公开(公告)号：US20170112685A1

公开(公告)日：2017-04-27

申请号：US15304139

申请日：2015-06-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Mahfuza B. Ali ,  Bathsheba E. Chong Conklin ,  Andrew P. Klein ,  Scott E. Langer

IPC: A61F13/53 ,  A61F13/15

CPC classification number: A61F13/53 ,  A61F13/15203 ,  A61F13/15577 ,  A61F2013/15463 ,  A61F2013/530642

Abstract: Described herein are absorbent articles and methods of making such articles. The articles are made by bonding a copolymer onto a substrate to form a core. The absorbent articles are particularly useful in personal care product, e.g., disposable hygiene products.

公开(公告)号：US09616394B2

公开(公告)日：2017-04-11

申请号：US14400810

申请日：2013-05-23

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Catherine A. Bothof ,  George W. Griesgraber ,  James I. Hembre ,  Jerald K. Rasmussen

IPC: B01D71/78 ,  B01D71/56 ,  B01D71/40 ,  B01D71/76 ,  C09D179/02 ,  G01N33/543 ,  C09D177/04 ,  C08F255/02 ,  C08G69/48 ,  B01J20/32 ,  C08G69/10 ,  C08G73/02

CPC classification number: B01D71/78 ,  B01D71/40 ,  B01D71/56 ,  B01D71/76 ,  B01D2323/30 ,  B01D2323/385 ,  B01D2325/12 ,  B01J20/261 ,  B01J20/264 ,  B01J20/321 ,  B01J20/3282 ,  B01J20/3293 ,  B01J20/3297 ,  C08F255/02 ,  C08F283/04 ,  C08G69/10 ,  C08G69/48 ,  C08G73/0206 ,  C08G73/022 ,  C08G73/028 ,  C08J7/18 ,  C08J2323/06 ,  C08J2323/12 ,  C08J2377/00 ,  C08J2433/14 ,  C09D177/04 ,  C09D179/02 ,  G01N33/54393 ,  G01N33/545

Abstract: Guanidinyl ligand-functionalized polymers, methods of making the same, and substrates bearing a grafted coating of the ligand-functional polymers are described. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, endotoxins and proteins, at pH's near or below the pI's of the biomaterials.

公开(公告)号：US20170049926A1

公开(公告)日：2017-02-23

申请号：US15342898

申请日：2016-11-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Delony L. Langer-Anderson ,  George W. Griesgraber ,  Semra Colak Atan ,  Junia M. Pereira ,  Katie F. Wlaschin ,  Alexi J. Young ,  Robert A. Asmus ,  David S. Hays ,  Jerald K. Rasmussen ,  Michael J. Solberg

IPC: A61L26/00

CPC classification number: A61L26/0066 ,  A61K9/7015 ,  A61K31/14 ,  A61K47/34 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/043 ,  A61L26/0004 ,  A61L26/0019 ,  A61L26/0052 ,  A61L26/0061 ,  A61L26/0095 ,  A61L2300/404 ,  A61L2300/418 ,  A61L2400/04 ,  A61L2430/34 ,  Y02A50/473 ,  C08L83/04

Abstract: Film forming gel compositions, useful in creating conformable and flexible gel bandages, can be formulate from a film forming polymer, a tackifier, and a volatile solvent. The film forming gels can also include antiseptics, cationic polymer coagulants, fillers, and other additives. The gel compositions form relatively thick films when dried on tissue, and can exhibit enhanced breathability to promote wound healing.

Abstract translation: 可用于形成适形和柔性凝胶绷带的成膜凝胶组合物可以由成膜聚合物，增粘剂和挥发性溶剂配制。 成膜凝胶也可以包括防腐剂，阳离子聚合物凝结剂，填料和其它添加剂。 凝胶组合物在组织上干燥时形成相对厚的膜，并且可以表现出增强的透气性以促进伤口愈合。

公开(公告)号：US20160339412A1

公开(公告)日：2016-11-24

申请号：US15228469

申请日：2016-08-04

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Catherine A. Bothof

IPC: B01J20/26 ,  C09D5/00 ,  C09D4/00 ,  C07K1/22 ,  B01J20/32 ,  C07K14/765 ,  C07K16/00 ,  C09D133/24 ,  C09D179/02

CPC classification number: B01J20/267 ,  B01J20/289 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3276 ,  B01J20/3278 ,  B01J20/3282 ,  C07K1/22 ,  C07K14/765 ,  C07K16/00 ,  C08G73/02 ,  C08J7/047 ,  C08J7/18 ,  C08J2333/24 ,  C08J2377/06 ,  C08J2433/14 ,  C08J2433/24 ,  C09D4/00 ,  C09D5/002 ,  C09D133/24 ,  C09D179/02 ,  G01N33/54393

Abstract: Ligand-functionalized substrates are describe that are useful in selectively binding and removing biological materials from biological samples, and methods for preparing the same.

公开(公告)号：US20160325268A1

公开(公告)日：2016-11-10

申请号：US15213572

申请日：2016-07-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Cary A. Kipke ,  Peter D. Wickert

IPC: B01J20/285 ,  B01J20/286 ,  B01D15/20 ,  B01D15/32 ,  C08F20/54 ,  C07C237/22

Abstract: A filtration media is disclosed comprising a hydrophobic monomer grafted onto a support, the hydrophobic monomer having the structure: CH2═CR4C(O)NHC(R1R1)(C(R1R1))nC(O)XR3 wherein n is an integer of 0 or 1; R1 is independently selected from at least one of: a hydrogen atom, alkyls, aryls, and alkylaryls, wherein the alkyls, aryls, and alkylaryls have a total of 10 carbon atoms or less; R3 is a hydrophobic group selected from at least one of: alkyls, aryls, alkylaryls and ethers, wherein the alkyls, aryls, alkylaryls and ethers have a total number of carbon atoms ranging from 4 to 30; R4 is H or CH3; X is O or NH. In some embodiments the hydrophobic monomer is derived from an amine or an alcohol (HXR3) that has a hydrophilicity index of 25 or less. Such media may be used in applications such as hydrophobic interaction chromatography.

Abstract translation: 其中n为0或1的整数; R 1独立地选自氢原子，烷基，芳基和烷基芳基中的至少一个，其中烷基，芳基和烷基芳基总共具有10个或更少的碳原子; R3是选自烷基，芳基，烷基芳基和醚中的至少一种的疏水基团，其中烷基，芳基，烷基芳基和醚的总碳原子数范围为4-30; R4是H或CH3; X是O或NH。 在一些实施方案中，疏水性单体衍生自亲水性指数为25以下的胺或醇（HXR3）。 这样的介质可以用于诸如疏水相互作用层析的应用中。