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公开(公告)号：US20210002008A1
公开(公告)日：2021-01-07
申请号：US17026156
申请日：2020-09-18
Applicant: Fenwal, Inc.
Inventor： Kyungyoon Min , Alexandra Salomon , Julie Griep , Christopher J. Wegener
Abstract: A variety of fill options is provided for a cell processing system. Certain options relate to a filling system associated with the cell processing system, the filling system comprising one or more filling stations, each with at least one container that may receive product from a container associated with a cell processing system. Other options relate to a syringe assembly that receives a product from a container associated with a cell processing system.
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公开(公告)号：US10525249B2
公开(公告)日：2020-01-07
申请号：US15448751
申请日：2017-03-03
Applicant: Fenwal, Inc.
Inventor： Christopher J. Wegener , Kyungyoon Min
Abstract: A device for connecting first and second medical fluid flow systems includes a linear movement carriage system that is positioned within a housing. The carriage system includes first and second connector holders configured to hold first and second connectors of the first and second medical fluid flow systems, respectively. A coupler holder is configured to hold a coupler and is positioned substantially between the first and second connector holders. The first and second connector holders and the coupler holder are relatively moveable between a separated configuration, where the first and second connectors and the coupler are located in relatively spaced apart positions, and a joined configuration, where the first and second connectors engage the coupler. An ultraviolet light source is positioned in the housing so as to irradiate first and second connectors and the coupler. A drive system transitions the first and second connector holders and the coupler holder between the separated and the joined configurations.
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73.发明申请公开(公告)号：US20190255233A1
公开(公告)日：2019-08-22
申请号：US16404347
申请日：2019-05-06
Applicant: Fenwal, Inc.
Inventor： Kyungyoon Min
Abstract: Methods and systems for reducing bacterial contamination of platelets are disclosed. The methods and systems disclosed herein provide for the processing of a pre-determined volume of whole blood so as to reduce the risk that platelets separated and collected from the whole blood have a reduced risk of bacterial contamination.
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74.发明申请公开(公告)号：US20190224494A1
公开(公告)日：2019-07-25
申请号：US16362824
申请日：2019-03-25
Applicant: Fenwal, Inc.
Inventor： Katherine N. Radwanski , Lan T. Nguyen , Kyungyoon Min , Cheryl Heber
IPC: A61N5/06 , C12N5/0781 , C12N5/0783 , C12N5/0786 , A01N1/02
Abstract: An apparatus and method for the batch photoactivation of mononuclear cells (MNCs) is described. The system includes a programmable controller configured to automatically separate whole blood in a first collection cycle to obtain a first quantity of MNCs; separate whole blood in a second collection cycle to obtain a second quantity of MNCs while simultaneously photoactivating the first quantity of MNCs to obtain a first quantity of treated MNCs; either store the first quantity of treated MNCs or reinfuse the first quantity of treated MNCs; photoactivate the second quantity of MNCs to obtain a second quantity of treated MNCs; either store the second quantity of treated MNCs or reinfuse the second quantity of treated MNCs; and reinfuse any blood components remaining after the second collection cycle. If the treated MNCs are to be stored, they may optionally be cryopreserved such that the treated MNCs retain their apoptotic properties after cryopreservation and subsequent thawing.
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75.发明申请公开(公告)号：US20190117870A1
公开(公告)日：2019-04-25
申请号：US16219153
申请日：2018-12-13
Applicant: Fenwal, Inc.
Inventor： Benjamin Kusters , Kyungyoon Min , Christopher Wegener
Abstract: A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously-collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
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Patent Agency Ranking
公开(公告)号：US10207044B2
公开(公告)日：2019-02-19
申请号：US15221657
申请日：2016-07-28
Applicant: Fenwal, Inc.
Inventor： Kyungyoon Min
Abstract: Systems and methods are provided for separating blood into two or more separated blood components. The system includes a blood separation chamber with a single stage having five ports connected thereto. The five ports include a blood inlet port, a red blood cell outlet port, a platelet-rich plasma outlet port, a platelet-poor plasma outlet port, and a buffy coat outlet port. In the single stage, blood may be separated into a variety of components, such as red blood cells and platelet-rich plasma or red blood cells, platelet-poor plasma, and buffy coat. Depending on the components into which the blood is to be separated, flow out of one or more of the outlet ports may be prevented.
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77.发明授权公开(公告)号：US10207042B2
公开(公告)日：2019-02-19
申请号：US15066047
申请日：2016-03-10
Applicant: Fenwal, Inc.
Inventor： Benjamin Kusters , Kyungyoon Min , Christopher Wegener
Abstract: A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously-collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
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78.发明申请公开(公告)号：US20180256721A1
公开(公告)日：2018-09-13
申请号：US15974914
申请日：2018-05-09
Applicant: Fenwal, Inc.
Inventor： Katherine Radwanski , Craig L. Sanford , Kyungyoon Min , Bryan Blickhan , Daniel Lynn , Tat Mui
CPC classification number: A61K45/06 , A01N1/0226 , A01N1/0263 , A01N1/0273 , A61J1/10 , A61J1/1468 , A61K35/18 , B32B27/08 , B32B27/304 , B32B27/32 , B32B2270/00 , B32B2307/7244 , B32B2439/80
Abstract: Red blood cell products and compositions are disclosed. The product includes a container made from PVC or a non-PVC material that is substantially free of a phthalate plasticizer but otherwise includes one or more non-phthalate plasticizers or extractable agents. The product includes a RBC concentrate which has been combined with an additive solution for storing the RBCs.
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79.发明申请公开(公告)号：US20180236405A1
公开(公告)日：2018-08-23
申请号：US15894307
申请日：2018-02-12
Applicant: Fenwal, Inc.
Inventor： Richard I. Brown , Benjamin E. Kusters , Kyungyoon Min
Abstract: A system for separating a suspension of biological cells is disclosed comprising a single-use fluid circuit and a durable hardware component. The fluid circuit comprises a separator having a housing that includes an inlet for introducing the suspension of biological cells into the gap, a first outlet in communication with the gap for flowing a first type of cells from the separator, and a second outlet in communication with the second side of the filter membrane for flowing a second type of cells from the separator. The hardware component comprises a pump for flowing the suspension of biological cells to the inlet of the separator and at least one flow control device associated with the first outlet and the second outlet of the separator for selectively opening and closing the outlets so as to permit one of the first type of cells and the second type of cells to flow out of the separator in accordance with a predetermined duty cycle equal to the ratio of a target flow rate of first type of cells through the first outlet to the predetermined inlet flow rate.
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公开(公告)号：US20180154054A1
公开(公告)日：2018-06-07
申请号：US15827828
申请日：2017-11-30
Applicant: Fenwal, Inc.
Inventor： Alexandra Salomon , Julie Griep , Kyungyoon Min , Christopher J. Wegener , Anand Raju
CPC classification number: A61M1/029 , A61J1/05 , A61M1/0209 , A61M1/0281 , A61M1/3692 , A61M2202/0427 , A61M2205/3393 , A61M2209/082 , A61M2209/084
Abstract: A device for pooling a blood component stored in source containers includes a pump or pumps configured to pump a fluid in a first direction and a second direction and receive a pump line having a first end connected to the source containers. A pool clamp is configured to receive a pool line having a first end connected to a second end of the pump line and a second end connected to a pool container. A wash clamp is configured to receive a wash line having a first end connected to the second end of the pump line and a second end connected to a wash media container. A controller is configured to open the pool clamp, close the wash clamp and operate the pump in the first direction and to alternatively close the pool clamp, open the wash clamp and operate the pump in the second direction.
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