公开(公告)号：US20210364517A1

公开(公告)日：2021-11-25

申请号：US17327151

申请日：2021-05-21

Applicant: The Penn State Research Foundation ,  The National Institute of Standards and Technology ,  University of North Carolina at Greensboro

Inventor： Vyacheslav V. ROTKIN ,  Ming ZHENG ,  Tetyana IGNATOVA ,  Daniel HAYES ,  Suresh KUCHIPUDI

IPC: G01N33/569 ,  G01N33/53 ,  G01N33/543 ,  G01N33/58

Abstract: The invention is directed to methods and systems for early detection of viral diseases, and more specifically to systems and methods for early detection of viral diseases that are capable of detecting very low viral loads, such as for example and not limitation, SARS-CoV-2 loads.

公开(公告)号：US10152666B2

公开(公告)日：2018-12-11

申请号：US14833187

申请日：2015-08-24

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY ,  Jung-Joon Ahn

Inventor： Yaw S. Obeng ,  Joseph J. Kopanski ,  Jung-Joon Ahn

IPC: G06K19/06 ,  G06K7/12

Abstract: An authentication article includes: a substrate including: a first surface; a second surface disposed laterally to the first surface and at a depth below the first surface; and a plurality of indentations including the depth at the second surface of the substrate; and an array disposed on the substrate and including a plurality of analytes, the analytes being disposed in the indentations at a depth below a first surface of the substrate and provided to emit an authentication signature in response to being subjected to a probe stimulus. A process for authenticating the authentication article includes: providing the authentication article; subjecting the analytes to a probe stimulus; acquiring a response from the plurality of analytes in response to being subjected to the probe stimulus; and determining whether the response is the authentication signature to authenticate the, wherein the authentication article is not authenticated if the response is not the authentication signature for the array.

公开(公告)号：US10127393B2

公开(公告)日：2018-11-13

申请号：US15215556

申请日：2016-07-20

Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： David Ferraiolo ,  Serban Gavrila ,  Gopi Katwala ,  Joshua Roberts

IPC: G06F21/62 ,  G06F21/60 ,  G06F17/30

Abstract: A computer-implemented method included: receiving, by an access manager, a query from a source; communicating the query from the access manager to a translator; translating the query into a next generation access control (NGAC) input; communicating the NGAC input to an NGAC engine, the NGAC engine including access control data; receiving the NGAC input; determining an authorization response; communicating the authorization response to the translator; translating the authorization response into a response statement; communicating the response statement to the access manager; communicating, if the response statement comprises a permitted statement: a permitted query to a database from the access manager, the permitted query comprising a data operation; and performing the data operation on data in the database; and blocking access by the source to data in the database if the response statement comprises a deny statement.

公开(公告)号：US10054286B2

公开(公告)日：2018-08-21

申请号：US14792184

申请日：2015-07-06

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： Christopher M. Brown ,  John T. Melcher ,  Stephan J. Stranick

IPC: G02B6/32 ,  F21V5/00 ,  F21V8/00 ,  G02B3/00 ,  G02B26/10

CPC classification number: F21V5/008 ,  G02B3/00 ,  G02B6/0005 ,  G02B6/0008 ,  G02B26/101 ,  G02B26/103 ,  G02B26/105 ,  Y10T29/49828

Abstract: An optical transformer includes: an optomechanical member configured: to receive incident light; and to produce primary light from the incident light including an initial propagation that includes a nonlinear scan; and a lens configured: to receive the primary light from the optomechanical member; to linearize the nonlinear scan; and to produce secondary light including a final propagation that comprises a linear scan, such that the optical transformer is configured to transform the nonlinear scan of the primary light to the linear scan of the secondary light. A process for optically transforming a nonlinear scan includes receiving an incident light by an optical transformer that includes an optomechanical member and a lens; producing a primary light from the incident light that includes an initial propagation having a nonlinear scan; communicating the primary light from to the lens; and producing a secondary light to optically transform the nonlinear scan, the secondary light including a final propagation that comprises a linear scan, based on optically linearizing the initial propagation.

公开(公告)号：US20180195199A9

公开(公告)日：2018-07-12

申请号：US15146888

申请日：2016-05-04

Applicant: SANG HYUN AHN ,  NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： THOMAS P. MOFFAT ,  YIHUA LIU ,  SANG HYUN AHN

IPC: C25D21/12 ,  H01L21/288 ,  C25D3/50 ,  C25D5/10

CPC classification number: C25D21/12 ,  C25B1/02 ,  C25D3/50 ,  C25D5/10 ,  C25D5/18 ,  C25D7/123 ,  H01L21/2885 ,  H01M4/8853 ,  H01M4/925 ,  H01M4/94

Abstract: A process for depositing a plurality of layers of iridium on a substrate includes: contacting the substrate with an electrolyte composition including: iridium cations protons; biasing the substrate at a first potential; forming iridium on the substrate at the first potential of the substrate; disposing hydrogen on the substrate; self-terminating the forming of iridium on the substrate in response to increasing a coverage of hydrogen on the substrate; oxidizing hydrogen on the substrate by changing a potential of the substrate from the first potential to a second potential; and changing the potential of the substrate from the second potential to a third potential for forming additional iridium on the substrate to deposit a plurality of layers of iridium on the substrate, such that forming the additional iridium on the substrate occurs at the third potential in response to oxidizing the hydrogen on the substrate at the second potential.

公开(公告)号：US09828677B2

公开(公告)日：2017-11-28

申请号：US14596349

申请日：2015-01-14

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： Owen Hildreth

IPC: H01L21/306 ,  C23C18/16 ,  C23C18/18 ,  C23C18/31 ,  H01L21/285 ,  H01Q17/00 ,  C25F3/12

CPC classification number: C23C18/1608 ,  C23C18/1879 ,  C23C18/31 ,  C25F3/12 ,  H01L21/28506 ,  H01L21/306 ,  H01L21/30604 ,  H01Q17/00

Abstract: A process for etching includes disposing an activating catalyst on a substrate; providing a vapor composition that includes an etchant oxidizer, an activatable etchant, or a combination thereof; contacting the activating catalyst with the etchant oxidizer; contacting the substrate with the activatable etchant; performing an oxidation-reduction reaction between the substrate, the activatable etchant, and the etchant oxidizer in a presence of the activating catalyst and the vapor composition; forming an etchant product that includes a plurality of atoms from the substrate; and removing the etchant product from the substrate to etch the substrate.

公开(公告)号：US20170115243A1

公开(公告)日：2017-04-27

申请号：US15275984

申请日：2016-09-26

Applicant: National Institute of Standards and Technology

Inventor： John J. Kasianowicz ,  Joseph E. Reiner ,  Arvind K. Balijepalli, III ,  Joseph W. Robertson ,  Daniel L. Burden ,  Lisa Burden

IPC: G01N25/00 ,  G01K7/16

CPC classification number: G01N25/00 ,  G01K7/16 ,  G01K2211/00

Abstract: Systems and methods for controlling the temperature of small volumes such as yoctoliter volumes, are described. The systems include one or more plasmonic nanostructures attached at or near a nanopore. Upon excitation of the plasmonic nanostructures, such as for example by exposure to laser light, the nanoparticles are rapidly heated thereby causing a change in the ionic conductance along the nanopore. The temperature change is determined from the ionic conductance. These temperature changes can be used to control rapid thermodynamic changes in molecular analytes as they interact with the nanopore.

公开(公告)号：US20170098548A9

公开(公告)日：2017-04-06

申请号：US14596349

申请日：2015-01-14

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： OWEN HILDRETH

IPC: H01L21/306

CPC classification number: C23C18/1608 ,  C23C18/1879 ,  C23C18/31 ,  C25F3/12 ,  H01L21/28506 ,  H01L21/306 ,  H01L21/30604 ,  H01Q17/00

Abstract: A process for etching includes disposing an activating catalyst on a substrate; providing a vapor composition that includes an etchant oxidizer, an activatable etchant, or a combination thereof; contacting the activating catalyst with the etchant oxidizer; contacting the substrate with the activatable etchant; performing an oxidation-reduction reaction between the substrate, the activatable etchant, and the etchant oxidizer in a presence of the activating catalyst and the vapor composition; forming an etchant product that includes a plurality of atoms from the substrate; and removing the etchant product from the substrate to etch the substrate.

公开(公告)号：US20170024572A1

公开(公告)日：2017-01-26

申请号：US15215556

申请日：2016-07-20

Applicant: USA, AS REPRESENTED BY THE SECRETARY OF COMMERCE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： DAVID FERRAIOLO ,  SERBAN GAVRILA ,  GOPI KATWALA ,  JOSHUA ROBERTS

IPC: G06F21/60 ,  G06F17/30 ,  G06F21/62

CPC classification number: G06F21/604 ,  G06F17/30165 ,  G06F17/30365 ,  G06F17/30424 ,  G06F17/30595 ,  G06F21/6227

Abstract: A computer-implemented method included: receiving, by an access manager, a query from a source; communicating the query from the access manager to a translator; translating the query into a next generation access control (NGAC) input; communicating the NGAC input to an NGAC engine, the NGAC engine including access control data; receiving the NGAC input; determining an authorization response; communicating the authorization response to the translator; translating the authorization response into a response statement; communicating the response statement to the access manager; communicating, if the response statement comprises a permitted statement: a permitted query to a database from the access manager, the permitted query comprising a data operation; and performing the data operation on data in the database; and blocking access by the source to data in the database if the response statement comprises a deny statement.

Abstract translation: 计算机实现的方法包括：由访问管理器接收来自源的查询; 将查询从访问管理器传达到翻译器; 将查询转换为下一代访问控制（NGAC）输入; 将NGAC输入传送给NGAC引擎，NGAC引擎包括访问控制数据; 接收NGAC输入; 确定授权响应; 将授权响应传达给翻译者; 将授权响应转换为响应语句; 将响应语句传达给访问管理器; 如果所述响应语句包括允许的语句，则从所述访问管理器向所述数据库发出允许的查询，所述允许的查询包括数据操作; 并对数据库中的数据执行数据操作; 并且如果响应语句包含拒绝语句，则阻止源访问数据库中的数据。

公开(公告)号：US09545584B2

公开(公告)日：2017-01-17

申请号：US14189619

申请日：2014-02-25

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： Constantine Y. Khripin ,  Ming Zheng

IPC: B01D11/02 ,  B01D15/02 ,  B01D17/02 ,  C01B31/02 ,  B03B5/00 ,  B82Y40/00

CPC classification number: B01D15/02 ,  B01D11/028 ,  B82Y40/00 ,  C01B32/172 ,  C01B2202/02 ,  C01B2202/22 ,  C01B2202/36

Abstract: A process for fractionating a nanoparticle composition, the process includes combining a first polymer, a second polymer, and a solvent to form a fluid and contacting the nanoparticle composition with the fluid. The nanoparticle composition includes a plurality of first nanoparticles, a plurality of second nanoparticles, and a dispersant disposed on an exterior surface of the first nanoparticles and the second nanoparticles. Fractionating the nanoparticle composition also includes forming a multiphase composition that includes a first phase and a second phase by partitioning the first polymer and the second polymer such that a concentration of the first polymer is greater than a concentration of the second polymer in the first phase, and the concentration of the second polymer is greater than the first polymer in the second phase, wherein the solvent is present in the first phase and the second phase. Additionally, the process includes apportioning the first nanoparticles and the second nanoparticles among the first phase and the second phase to fractionate the nanoparticle composition, based on a relative affinity of the first nanoparticles and the second nanoparticles for the first polymer and the second polymer, wherein the first nanoparticles are present in the first phase and substantially absent in the second phase, and the second nanoparticles are present in the second phase and substantially absent in the first phase.

Abstract translation: 一种用于分级纳米颗粒组合物的方法，该方法包括组合第一聚合物，第二聚合物和溶剂以形成流体并使纳米颗粒组合物与流体接触。 纳米颗粒组合物包括多个第一纳米颗粒，多个第二纳米颗粒和设置在第一纳米颗粒和第二纳米颗粒的外表面上的分散剂。 分级纳米颗粒组合物还包括通过分隔第一聚合物和第二聚合物形成包含第一相和第二相的多相组合物，使得第一聚合物的浓度大于第一相中第二聚合物的浓度， 并且第二聚合物的浓度大于第二相中的第一聚合物，其中溶剂存在于第一相和第二相中。 另外，该方法包括基于第一种纳米颗粒和第二种纳米颗粒对第一种聚合物和第二种聚合物的相对亲和力，在第一相和第二相中分配第一种纳米颗粒和第二种纳米颗粒以分级纳米颗粒组合物，其中 第一种纳米颗粒存在于第一相中，并且在第二相中基本上不存在，而第二种纳米颗粒存在于第二相中，并且在第一相中基本不存在。