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    Compact analyzer for dry biochemical analysis of blood samples
    81.
    发明申请
    Compact analyzer for dry biochemical analysis of blood samples 审中-公开
    用于血液样品干生化分析的紧凑型分析仪

    公开(公告)号：US20070077173A1

    公开(公告)日：2007-04-05

    申请号：US11541555

    申请日：2006-10-03

    Applicant: Francois Melet

    Inventor： Francois Melet

    IPC: G01N35/00

    CPC classification number: G01N21/253 ,  G01N21/274 ,  G01N21/31 ,  G01N35/00069 ,  G01N35/025 ,  G01N2021/3133 ,  G01N2021/3166 ,  G01N2021/3177 ,  G01N2201/0415 ,  G01N2201/06186 ,  G01N2201/12792 ,  G01N2201/1285

    Abstract: A compact analyzer for dry biochemical analysis of blood samples, integrating onto a common chassis (11): a measuring chamber (20) adapted to receive a disposable rotor (13) including microtanks (13A, 13B) containing dry reagents, a digital dilution module (21) of fixed or variable ratio defined as a function of the species of the sample to be analyzed, a sample centrifuging module (12) adapted, inside the measuring chamber, to centrifuge the rotor and position it angularly, an optical module adapted to apply beams of light to microtanks of the rotor, this optical module including a flash-lamp type light source (14) and a reference light sensor (16), an electronic processing and control system (23, 24, 25) including an external memory reader (26) adapted to read a portable external memory (27) containing at least information characteristic of at least the disposable rotor in use.

    Abstract translation: 一种用于血液样品的干生物化学分析的紧凑型分析仪，集成到公共底盘（11）上：测量室（20），其适于容纳包含含有干试剂的微量池（13A，13B）的一次性转子（13），数字 固定或可变比率的稀释模块（21），其定义为待分析样品的种类的函数;样品离心模块（12），其适于在所述测量室内部离心转子并将其定位，光学模块 该光学模块包括闪光灯型光源（14）和参考光传感器（16），电子处理和控制系统（23,24,25）包括： 外部存储器读取器（26）适于读取至少包含使用中的一次性转子的信息特征的便携式外部存储器（27）。

    Surface plasmon resonance measuring chip and method of manufacture thereof
    85.
    发明申请
    Surface plasmon resonance measuring chip and method of manufacture thereof 审中-公开
    表面等离子共振测量芯片及其制造方法

    公开(公告)号：US20020127706A1

    公开(公告)日：2002-09-12

    申请号：US10053585

    申请日：2002-01-24

    Applicant: FUJI PHOTO FILM CO., LTD.

    Inventor： Masayuki Naya ,  Takashi Kubo ,  Takashi Ito ,  Yoshimitsu Nomura

    IPC: C12M001/34 ,  G01J003/42 ,  G01J003/427

    CPC classification number: G01N21/553 ,  B29C45/0025 ,  B29C2045/0027 ,  G01N2201/0415

    Abstract: A surface plasmon resonance measuring apparatus is provided with a dielectric block, a metal film formed on a surface of the dielectric block, a light source for emitting a light beam, an optical system for making the light beam enter the dielectric block at various angles of incidence so that a condition for total internal reflection is satisfied at an interface between the dielectric block and the thin film layer, and a photodetector for detecting the intensity of the light beam satisfying total internal reflection at the interface. In the measurement chip to be utilized in the surface plasmon resonance measuring apparatus, the dielectric block is formed from a synthetic resin in which, when said light beam is p-polarized outside said dielectric block and then strikes the interface, the intensity of a s-polarized component at the interface is 50% or less of the intensity of the light beam at the interface.

    Abstract translation: 表面等离子体共振测定装置具备介质块，形成在介质块的表面上的金属膜，用于发射光束的光源，使光束以各种角度进入介质块的光学系统 入射，使得在介电块和薄膜层之间的界面处满足全内反射条件，以及用于检测在界面处满足全内反射的光束的强度的光电检测器。 在表面等离子体共振测定装置中使用的测量芯片中，介电块由合成树脂形成，其中当所述光束在所述介质块外部p偏振，然后撞击界面时，s的强度 界面处的极化分量为界面光束强度的50％以下。

    Photoelectric measuring apparatus for use in automatic analyzer
    86.
    发明授权
    Photoelectric measuring apparatus for use in automatic analyzer 失效
    用于自动分析仪的光电测量仪

    公开(公告)号：US4950077A

    公开(公告)日：1990-08-21

    申请号：US343681

    申请日：1989-04-27

    Applicant: Sugio Manabe

    Inventor： Sugio Manabe

    IPC: G01J3/10 ,  G01J3/18 ,  G01J3/28 ,  G01N21/25 ,  G01N21/27 ,  G01J3/42

    CPC classification number: G01N21/253 ,  G01J3/18 ,  G01J3/2803 ,  G01N2201/0407 ,  G01N2201/0415 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: A photoelectric measuring apparatus for use in an automatic chemical analyzer in which a plurality of test items are analyzed by using light beams having different wavelengths, including a white light source for emitting a polychromatic light beam, a grating for diffracting the polychromatic light beam into a plurality of light beams having predetermined different wavelengths, a plurality of light guides for guiding the light beams emanating from the grating to a plurality of cuvettes containing test liquids to be analyzed, a plurality of light receiving elements for receiving light beams transmitted through the cuvettes, an additional light guide for guiding a polychromatic light beam emanating from the grating as the zero order light beam to a cuvette via an optical filter having a desired transmission wavelength, and an additional light receiving element for receiving a light beam transmitted through the cuvette.

    Abstract translation: 一种用于自动化学分析仪的光电测量装置，其中通过使用具有不同波长的光束来分析多个测试项目，所述光束包括用于发射多色光束的白色光源，用于将多色光束衍射为 具有预定不同波长的多个光束，用于将从光栅发射的光束引导到包含待分析测试液体的多个比色杯的多个光导;多个用于接收透过比色杯的光束的光接收元件， 用于将通过具有期望的透射波长的滤光器将从光栅发出的多色光束作为零级光束引导到比色杯的附加光导，以及用于接收透射通过比色杯的光束的附加光接收元件。

    Instrument for independently and kinetically measuring light transpassion through a plurality of samples
    87.
    发明授权
    Instrument for independently and kinetically measuring light transpassion through a plurality of samples 失效
    用于通过多个样品独立地和动态地测量光透过的仪器

    公开(公告)号：US4936682A

    公开(公告)日：1990-06-26

    申请号：US084098

    申请日：1987-08-11

    Applicant: Joshua K. Hoyt

    Inventor： Joshua K. Hoyt

    IPC: G01N35/02 ,  G01N21/25 ,  G01N21/27

    CPC classification number: G01N21/253 ,  G01N2201/0407 ,  G01N2201/0415 ,  G01N2201/0476

    Abstract: An analytic instrument for kinetically measuring light absorption characteristics of a plurality of independent samples contained in disposable test tubes arranged in a circular pattern about a single light source. The instrument is designed to be used with a host personal computer and is not specific to any particular type of assay. The instrument obtains and temporarily stores raw data in the form of digitized output signals from the plurality of photodetectors and periodically passes them to the host computer. An incubator has test tube wells arranged in a circular array equidistant from a single incandescent light source. The circular symmetry controls the thermal gradients in the incubator such that all of the samples are disposed on the same isotherm and all of the photodetectors are disposed on the same isotherm. The instrument is designed for use with disposable test tubes, and sources of error arising from optical variation in such test tubes are minimized by providing a separate detector for each tube and by holding the tube fixed with respect to the detector. The light output from the single light source is continuously monitored and is kept constant.

    Spectrograph for evaluating contamination of optical components in space
    88.
    发明授权
    Spectrograph for evaluating contamination of optical components in space 失效
    用于评估空间光学元件污染的光谱仪

    公开(公告)号：US4815842A

    公开(公告)日：1989-03-28

    申请号：US868798

    申请日：1986-05-29

    Applicant: Bruce K. Flint ,  Robert D. Fancy ,  Robert V. Jarratt, Jr.

    Inventor： Bruce K. Flint ,  Robert D. Fancy ,  Robert V. Jarratt, Jr.

    IPC: G01J3/42 ,  G01N21/33 ,  G01N21/13 ,  G01J3/32

    CPC classification number: G01J3/42 ,  G01J2003/421 ,  G01J2003/425 ,  G01N2021/1742 ,  G01N2021/335 ,  G01N2201/0415

    Abstract: A monochromatic spectrometer for evaluating contamination changes in the surface condition of lenses, reflectors and similar optical samples in the vacuum of a space mission includes a vacuum ultraviolet beam source redirected from a dispersion grating through a test station and reflected from a mirror to a photodetector. A rotatable carrier supports two or more optical samples, both transmissive and reflective and selectively positions one sample at a time at the test station so that the selected sample modifies the VUV beam according to its surface condition. The mirror is movable from a first position in which it reflects the beam transmitted through a sample to second position in which it reflects the beam reflected from a sample. The sample condition measured by the photodetector, the position of the rotatable carrier and mission elapsed time are recorded in a memory for re-transmission or later read out.

    Abstract translation: 用于评估空间任务的真空中的透镜，反射器和类似光学样品的表面状况的污染变化的单色光谱仪包括从分散光栅重新定向穿过测试台并从反射镜反射到光电检测器的真空紫外光束源。 可旋转载体支持透射和反射的两个或更多个光学样品，并且在测试台一次选择性地定位一个样品，使得所选择的样品根据其表面条件修改VUV光束。 反射镜可以从第一位置移动，在第一位置，反射通过样品的光束反射从样品反射的光束到第二位置。 由光电检测器测量的样品状态，可旋转载体的位置和任务经过时间被记录在用于再传输或稍后读出的存储器中。

    Procedure for photometric measurement of liquids in reaction vessels, and reaction vessel
    89.
    发明授权
    Procedure for photometric measurement of liquids in reaction vessels, and reaction vessel 失效
    反应容器和反应容器中液体的光度测量程序

    公开(公告)号：US4690900A

    公开(公告)日：1987-09-01

    申请号：US462046

    申请日：1983-01-28

    Applicant: Kayhko Kimmo ,  Kari H. Helenius

    Inventor： Kayhko Kimmo ,  Kari H. Helenius

    IPC: G01N21/76 ,  B01J19/00 ,  G01N21/03 ,  G01N21/17 ,  G01N21/25 ,  G01N21/59

    CPC classification number: G01N21/251 ,  G01N21/03 ,  G01N21/59 ,  G01N2021/0357 ,  G01N2021/0378 ,  G01N2021/0392 ,  G01N21/0303 ,  G01N21/76 ,  G01N2201/0415 ,  G01N2201/0438 ,  G01N2201/122 ,  G01N2201/1242 ,  Y10T436/113332

    Abstract: A procedure for photometric measurement of liquids in a reaction vessel in an automatic analyser, with a radiation flow having its course perpendicular to a row of the reaction vessel, so as to provide a reliable and positively operating measuring method for the photometric measurement of the liquids. The procedure is characterized in that the radiation flow and the reaction vessel are in movement relative to each other during the measurement. The invention affords the advantage of improved accuracy of measurement and improved reliability since it becomes possible, by measuring a moving object and at the same time calculating the mean of the radiant flux over accepted portions of the signal, to eliminate the error of measurement introduced by a dirt particle or by a scratch. The invention also concerns a row of reaction vessels employed in the procedure, wherein each reaction vessel is contiguous to the next and separated by a wall. The row of reaction vessels is characterized in that the bottom of each reaction vessel consists of a lens focussing luminescence radiation. This affords the advantage that the lens enables a luminiscence measurement to be performed simultaneously with the photometric measurement.

    Abstract translation: 一种自动分析仪中的反应容器中的液体的光度测量程序，其辐射流程垂直于反应容器的一排，以便提供可靠和积极的测量方法，用于液体的光度测量 。 该过程的特征在于在测量期间辐射流和反应容器相对于彼此运动。 本发明提供了提高测量精度和提高可靠性的优点，因为通过测量移动物体并同时计算辐射通量超过信号接收部分的平均值，可消除由 污垢颗粒或划痕。 本发明还涉及在该方法中使用的一排反应容器，其中每个反应容器与下一个连续并由壁隔开。 反应容器的一排的特征在于每个反应容器的底部由聚焦发光辐射的透镜组成。 这提供了这样的优点，即透镜使得能够与光度测量同时进行亮度测量。

    Cuvette positioning device for optical analytical apparatus
    90.
    发明授权
    Cuvette positioning device for optical analytical apparatus 失效
    用于光学分析仪器的比色杯定位装置

    公开(公告)号：US4090789A

    公开(公告)日：1978-05-23

    申请号：US702473

    申请日：1976-07-06

    Applicant: James H. Macemon ,  Charles Soodak

    Inventor： James H. Macemon ,  Charles Soodak

    IPC: G01N21/13 ,  G01N21/25 ,  G01J3/30

    CPC classification number: G01N21/253 ,  G01N2201/0415

    Abstract: Cuvette positioning apparatus for use in a spectrophotometer adapted for comparing first and second material samples includes a carrier in which cuvettes to be alternately analyzed are arranged end-to-end. The carrier is reciprocated along a vertical axis to expose the cuvettes in alternation to the monochromatic beam of the apparatus. The rate of reciprocation is selected to avoid cavitation of the samples, and a sinusoidal drive arrangement increases the exposure time of the samples to the light beam and minimizes transit time for optimum measurement efficiency. Circuitry responsive to synchronizing signals derived from the drive arrangement is utilized to form an output signal indicative of the difference in measured characteristics between the samples.

    Abstract translation: 用于比较第一和第二材料样品的分光光度计中的比色杯定位装置包括载体，其中交替分析的比色杯端对端地排列。 载体沿着垂直轴线往复运动，以使试管与设备的单色光束交替地暴露。 选择往复运动的速率以避免样品的气蚀，并且正弦驱动装置增加了样品对光束的曝光时间，并将传播时间最小化以获得最佳的测量效率。 利用响应于从驱动装置导出的同步信号的电路来形成指示样本之间的测量特性差异的输出信号。

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