公开(公告)号：US09001854B2

公开(公告)日：2015-04-07

申请号：US13566790

申请日：2012-08-03

Applicant: Matthew S. Taubman ,  Mark C. Phillips

Inventor： Matthew S. Taubman ,  Mark C. Phillips

IPC: H01S3/13 ,  H01S5/068 ,  G01N21/39 ,  H01S5/00 ,  B82Y20/00 ,  G01N21/03 ,  H01S5/06 ,  H01S5/0687 ,  H01S5/14 ,  H01S5/34 ,  G01N21/77

CPC classification number: H01S5/06808 ,  B82Y20/00 ,  G01N21/031 ,  G01N21/39 ,  G01N2021/399 ,  G01N2021/7776 ,  G01N2201/0612 ,  H01S5/0028 ,  H01S5/0617 ,  H01S5/06832 ,  H01S5/0687 ,  H01S5/14 ,  H01S5/141 ,  H01S5/143 ,  H01S5/3401 ,  H01S5/3402

Abstract: A method is disclosed for power normalization of spectroscopic signatures obtained from laser based chemical sensors that employs the compliance voltage across a quantum cascade laser device within an external cavity laser. The method obviates the need for a dedicated optical detector used specifically for power normalization purposes. A method is also disclosed that employs the compliance voltage developed across the laser device within an external cavity semiconductor laser to power-stabilize the laser mode of the semiconductor laser by adjusting drive current to the laser such that the output optical power from the external cavity semiconductor laser remains constant.

Abstract translation: 公开了一种用于从激光基化学传感器获得的光谱特征的功率归一化的方法，其在外腔激光器内采用量子级联激光器件上的顺应性电压。 该方法避免了专门用于功率归一化目的的专用光学检测器的需要。 还公开了一种采用在外腔半导体激光器内横跨激光器件产生的顺从电压的方法，通过调节对激光器的驱动电流来对半导体激光器的激光模式进行功率稳定化，使得来自外腔半导体的输出光功率 激光保持恒定。

公开(公告)号：US20150085287A1

公开(公告)日：2015-03-26

申请号：US14557489

申请日：2014-12-02

Applicant: SICK AG

Inventor： Martin WUSTEFELD

IPC: G01N21/59 ,  G01N21/47

CPC classification number: G01N21/59 ,  G01N21/47 ,  G01N21/4738 ,  G01N2201/0612 ,  G01S7/497 ,  G01S2007/4975

Abstract: The invention relates to an attachment for placement onto an optical sensor having a housing with an inlet opening for the entry of detection light into the attachment, a test light receiver for receiving light incident at the test light receiver and for a power measurement of the light incident at the test light receiver as test light and having a signal outputting device for outputting an output signal correlated to the test light power. The invention moreover relates to a combination of an optical sensor and such an attachment and to a method for operating an optical sensor which method can be carried out with such an attachment.

Abstract translation: 本发明涉及一种用于放置在光学传感器上的附件，该光学传感器具有壳体，该壳体具有用于将检测光进入附件的入口，用于接收入射在测试光接收器处的光并用于光的功率测量的测试光接收器 在测试光接收器处作为测试光，并具有用于输出与测试光功率相关的输出信号的信号输出装置。 此外，本发明涉及光学传感器和这种附件的组合以及用于操作光学传感器的方法，该方法可以用这种附件来执行。

公开(公告)号：US08988678B2

公开(公告)日：2015-03-24

申请号：US13221899

申请日：2011-08-31

Applicant: Mark Watson ,  Shane Buller ,  Keith Carron

Inventor： Mark Watson ,  Shane Buller ,  Keith Carron

IPC: G01J3/00 ,  G01J3/06 ,  G01J3/44 ,  G01N21/65

CPC classification number: G01J3/4406 ,  G01J3/06 ,  G01J3/44 ,  G01J2003/062 ,  G01J2003/064 ,  G01N21/65 ,  G01N21/658 ,  G01N33/54313 ,  G01N33/54373 ,  G01N2201/0612

Abstract: A spectrometer is provided. In one implementation, for example, a spectrometer comprises an excitation source, a focusing lens, a movable mirror, and an actuator assembly. The focusing lens is adapted to focus an incident beam from the excitation source. The actuator assembly is adapted to control the movable mirror to move a focused incident beam across a surface of the sample.

Abstract translation: 提供光谱仪。 在一个实施方案中，例如，光谱仪包括激发源，聚焦透镜，可移动反射镜和致动器组件。 聚焦透镜适于聚焦来自激发源的入射光束。 致动器组件适于控制可移动镜以将聚焦的入射光束移动穿过样品的表面。

公开(公告)号：US08981298B2

公开(公告)日：2015-03-17

申请号：US13447494

申请日：2012-04-16

Applicant: Matthias Wagner ,  John Heanue

Inventor： Matthias Wagner ,  John Heanue

IPC: G01N21/35 ,  G01N21/3563 ,  C12N5/071 ,  G01N15/14 ,  B07C5/34

CPC classification number: G01N15/1436 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0627 ,  B01L2300/0864 ,  B07C5/34 ,  C12N5/0612 ,  G01N15/14 ,  G01N15/1427 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N15/1463 ,  G01N15/147 ,  G01N15/1484 ,  G01N21/1702 ,  G01N21/3563 ,  G01N29/2418 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/149 ,  G01N2015/1497 ,  G01N2201/0612

Abstract: This disclosure concerns a pathogen inspection system that includes a handling system that presents single cells from a sample to at least one QCL laser source. The QCL laser source is configured to deliver light to a cell within the cells in order to induce vibrational bond absorption in one or more analytes within the cell. The system includes a detection facility that detects the mid-infrared wavelength light transmitted by the cell and identifies the cell as either a pathogen or not a pathogen.

Abstract translation: 本公开涉及病原体检查系统，其包括将单个细胞从样品呈现至至少一个QCL激光源的处理系统。 QCL激光源被配置为将光传送到细胞内的细胞，以便在细胞内的一种或多种分析物中诱导振动键吸收。 该系统包括检测装置，其检测由细胞透射的中红外波长的光，并将细胞识别为病原体或不是病原体。

公开(公告)号：US20150069240A1

公开(公告)日：2015-03-12

申请号：US14539465

申请日：2014-11-12

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Kohei TAKAHASHI ,  Tsutomu KANNO ,  Akihiro SAKAI ,  Yuka YAMADA

IPC: H01S1/00 ,  G01N21/59 ,  G21K5/02 ,  G01N21/3581

CPC classification number: H01S1/00 ,  G01N21/3581 ,  G01N21/3586 ,  G01N21/59 ,  G01N2201/0612 ,  G01N2201/0697 ,  G02F1/355 ,  G02F2203/13 ,  G21K5/02 ,  H01L35/16

Abstract: A terahertz electromagnetic wave generator according to the present disclosure includes: a thermoelectric material layer; and a light source system which is configured to irradiate the thermoelectric material layer with pulsed light and generate a terahertz wave from the thermoelectric material layer. The thermoelectric material layer includes a gradient portion in which transmittance of the pulsed light varies in a certain direction. And the light source system is configured to irradiate the gradient portion of the thermoelectric material layer with the pulsed light.

Abstract translation: 根据本公开的太赫兹电磁波发生器包括：热电材料层; 以及光源系统，其被配置为用脉冲光照射所述热电材料层并从所述热电材料层产生太赫兹波。 热电材料层包括梯度部分，其中脉冲光的透射率在某个方向上变化。 并且光源系统被配置为用脉冲光照射热电材料层的梯度部分。

公开(公告)号：US20150062588A1

公开(公告)日：2015-03-05

申请号：US14482644

申请日：2014-09-10

Applicant: Fibersonics Inc.

Inventor： Edward Tapanes

IPC: G01B9/02 ,  G01N21/88

CPC classification number: G01B9/02041 ,  G01B9/02 ,  G01B9/02012 ,  G01B9/02027 ,  G01B9/02049 ,  G01B9/02079 ,  G01B2290/70 ,  G01D5/35306 ,  G01D5/35325 ,  G01D5/35329 ,  G01N21/8806 ,  G01N2201/0612 ,  G01N2201/088 ,  G02B6/255 ,  G02B6/36 ,  Y10T29/49826

Abstract: A fiber-optic sensor can have a Michelson sensor portion and a Mach-Zehnder sensor portion. A first splitter-coupler can be configured to split incoming light between a first fiber portion and a second fiber portion. A first polarization-phase conjugation device can be configured to conjugate a polarization phase of incident light corresponding to the first fiber portion, and a second polarization-phase conjugation device can be configured to conjugate a polarization phase of incident light corresponding to the second fiber portion. Each of the first and second polarization-phase conjugation devices can be configured to reflect light toward a detector and through the respective first and second fiber portions. A coupler can be configured to join light in the first fiber portion with light in the second fiber portion, and a third fiber portion can be configured to receive light from the coupler and to illuminate a second detector.

Abstract translation: 光纤传感器可以具有迈克尔逊传感器部分和马赫 - 曾德传感器部分。 第一分离器耦合器可以被配置为在第一光纤部分和第二光纤部分之间分离入射光。 第一偏振相位共轭装置可以被配置为将对应于第一光纤部分的入射光的偏振相位共轭，并且第二偏振相位共轭装置可以被配置为将对应于第二光纤部分的入射光的偏振相位共轭 。 第一和第二偏振相位共轭装置中的每一个可以被配置为将光朝向检测器反射并通过相应的第一和第二光纤部分。 耦合器可以被配置为将第一光纤部分中的光与第二光纤部分中的光结合，并且第三光纤部分可以被配置为从耦合器接收光并照亮第二检测器。

公开(公告)号：US20150037876A1

公开(公告)日：2015-02-05

申请号：US14175554

申请日：2014-02-07

Applicant: Samsung Electronics Co., Ltd.

Inventor： Kyung-ho Kim ,  Won-seok Chung ,  Sung-min Chi ,  Joon-ho Kim ,  Kak Namkoong ,  Chin-sung Park

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N2021/6421 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/103 ,  G01N2201/1053

Abstract: Provided are a multi-channel fluorescence detecting module and a nucleic acid analysis system including the multi-channel fluorescence detecting module. The nucleic acid analysis system includes: a plurality of loaders configured to accommodate a plurality of cartridges respectively, the cartridges comprising microfluidic devices; a transfer module including a linear actuator, the linear actuator including a movable unit configured to move linearly; and a fluorescence detecting module fixed to the movable unit, the fluorescence detecting module being configured to emit excitation light to the cartridges and detect fluorescence emitted from samples on the cartridges. The loaders are arranged in a row in a linearly moving direction of the movable unit.

Abstract translation: 提供了多通道荧光检测模块和包括多通道荧光检测模块的核酸分析系统。 所述核酸分析系统包括：多个装载器，其分别容纳多个盒，所述盒包括微流体装置; 包括线性致动器的转移模块，所述线性致动器包括构造成线性运动的可移动单元; 以及荧光检测模块，其固定到所述可移动单元，所述荧光检测模块被配置为向所述盒发射激发光并检测从所述盒上的样品发出的荧光。 装载机沿可移动单元的线性移动方向排成一列。

公开(公告)号：US08947656B2

公开(公告)日：2015-02-03

申请号：US13801978

申请日：2013-03-13

Applicant: The Board of Trustees of the University of Illinois

Inventor： Brian T. Cunningham

IPC: G01J3/28 ,  G01J3/44 ,  G01N21/63

CPC classification number: H04M1/72527 ,  G01J3/0202 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/28 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/25 ,  G01N21/31 ,  G01N21/553 ,  G01N21/63 ,  G01N21/6428 ,  G01N21/6445 ,  G01N21/6486 ,  G01N21/658 ,  G01N21/7746 ,  G01N2021/6417 ,  G01N2201/0612 ,  G01N2201/062

Abstract: A mobile computing device that includes an image sensor may be used to detect the result of a biomolecular assay. The biomolecular assay may be performed in an optical assay medium that provides an optical output in response to light from a light source, with the optical output indicating result. A wavelength-dispersive element may be used to disperse the optical output into spatially-separated wavelength components. The mobile computing device may be positioned relative to the wavelength-dispersive element such that different wavelength components are received at different locations on the image sensor. With the mobile computing device positioned in this way, the image sensor may be used to obtain one or more images that include the separated wavelength components of the optical output. A wavelength spectrum of the optical output may be determined from the one or more images, and the result may be determined from the wavelength spectrum.

Abstract translation: 可以使用包括图像传感器的移动计算设备来检测生物分子测定的结果。 生物分子测定可以在光学测定介质中进行，光学测定介质响应于来自光源的光而提供光学输出，光学输出指示结果。 波长分散元件可以用于将光输出分散到空间分离的波长分量中。 移动计算设备可以相对于波长分散元件定位，使得在图像传感器上的不同位置处接收不同的波长分量。 利用以这种方式定位的移动计算设备，可以使用图像传感器来获得包括光输出的分离的波长分量的一个或多个图像。 可以从一个或多个图像确定光学输出的波长谱，并且可以根据波长谱确定结果。

公开(公告)号：US08941062B2

公开(公告)日：2015-01-27

申请号：US13298148

申请日：2011-11-16

Applicant: Matthias Wagner ,  John Heanue

Inventor： Matthias Wagner ,  John Heanue

IPC: G01N21/35 ,  C12N5/071 ,  G01N15/14 ,  B07C5/34

CPC classification number: G01N15/1436 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0627 ,  B01L2300/0864 ,  B07C5/34 ,  C12N5/0612 ,  G01N15/14 ,  G01N15/1427 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N15/1463 ,  G01N15/147 ,  G01N15/1484 ,  G01N21/1702 ,  G01N21/3563 ,  G01N29/2418 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/149 ,  G01N2015/1497 ,  G01N2201/0612

Abstract: In embodiments of the present invention, a system and method of cytometry may include presenting a single sperm cell to at least one laser source configured to deliver light to the sperm cell in order to induce bond vibrations in the sperm cell DNA, and detecting the signature of the bond vibrations. The bond vibration signature is used to calculate a DNA content carried by the sperm cell which is used to identify the sperm cell as carrying an X-chromosome or Y-chromosome. Another system and method may include flowing cells past at least one QCL source one-by-one using a fluid handling system, delivering QCL light to a single cell to induce resonant mid-IR absorption by one or more analytes of the cell, and detecting, using a mid-infrared detection facility, the transmitted mid-infrared wavelength light, wherein the transmitted mid-infrared wavelength light is used to identify a cell characteristic.

Abstract translation: 在本发明的实施方案中，细胞计数的系统和方法可以包括将至少一个激光源呈现单精子细胞，所述至少一个激光源被配置为向精子细胞传送光，以诱导精子细胞DNA中的键振动，并检测签名 的键振动。 键振动特征用于计算精子细胞携带的DNA含量，用于鉴定精子细胞携带X染色体或Y染色体。 另一种系统和方法可以包括使用流体处理系统逐个流过细胞至少一个QCL源，将QCL光递送到单个细胞以诱导由该细胞的一种或多种分析物的共振中红外吸收，以及检测 使用中红外检测设备，所传输的中红外波长光，其中所发射的中红外波长光用于识别单元特性。

公开(公告)号：US20140243617A1

公开(公告)日：2014-08-28

申请号：US14271041

申请日：2014-05-06

Applicant: Valencell, Inc.

Inventor： Steven Francis LeBoeuf ,  Jesse Berkley Tucker ,  Michael Edward Aumer

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/103 ,  A61B5/11 ,  A61B5/1455 ,  A61B5/0476

CPC classification number: A61B5/02055 ,  A61B5/0002 ,  A61B5/0013 ,  A61B5/0015 ,  A61B5/0022 ,  A61B5/0059 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/024 ,  A61B5/02427 ,  A61B5/02438 ,  A61B5/026 ,  A61B5/029 ,  A61B5/031 ,  A61B5/04 ,  A61B5/04001 ,  A61B5/0476 ,  A61B5/0496 ,  A61B5/0533 ,  A61B5/0816 ,  A61B5/087 ,  A61B5/1032 ,  A61B5/11 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/112 ,  A61B5/1126 ,  A61B5/12 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/14556 ,  A61B5/1477 ,  A61B5/222 ,  A61B5/224 ,  A61B5/4064 ,  A61B5/411 ,  A61B5/415 ,  A61B5/418 ,  A61B5/4205 ,  A61B5/4227 ,  A61B5/4266 ,  A61B5/4542 ,  A61B5/4806 ,  A61B5/4812 ,  A61B5/4839 ,  A61B5/4845 ,  A61B5/4848 ,  A61B5/486 ,  A61B5/4866 ,  A61B5/4872 ,  A61B5/4875 ,  A61B5/6803 ,  A61B5/6815 ,  A61B5/6816 ,  A61B5/6817 ,  A61B5/6887 ,  A61B5/7203 ,  A61B5/721 ,  A61B5/7405 ,  A61B5/742 ,  A61B7/00 ,  A61B7/04 ,  A61B2560/0242 ,  A61M37/00 ,  A61M2037/0007 ,  A61N1/325 ,  G01D11/00 ,  G01N21/47 ,  G01N21/59 ,  G01N2201/021 ,  G01N2201/0612 ,  G01N2201/062

Abstract: Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.

Abstract translation: 提供了用于监测各种生理和环境因素的穿戴式装置。 实时，无创的健康和环境监测器包括集成在小型，薄型设备（如耳机模块）内的多个紧凑型传感器。 收集生理和环境数据并将其无线传输到数据被存储和/或处理的无线网络中。