Preparation method of zaleplon
    1.
    发明授权

    公开(公告)号:US12195474B2

    公开(公告)日:2025-01-14

    申请号:US17568851

    申请日:2022-01-05

    Abstract: A preparation method of zaleplon is provided and belongs to the technical field of pharmaceutical chemistry. The preparation method adopts simple and cheap m-nitrobenzaldehyde and triethylamine as raw materials, and constructs a core structure of zaleplon with high efficiency and high selectivity through a one-pot series reaction without transition metal catalysis, thereby avoiding the formation of isomers, reducing the generation of by-products, increasing the yield of target products and reducing the synthesis cost; and after simple nitro reduction modification, zaleplon is prepared. The method has the advantages of short preparation route, mild reaction conditions and simple operation, so the method is suitable for industrial production.

    DEEP REINFORCEMENT LEARNING INTELLIGENT DECISION-MAKING PLATFORM BASED ON UNIFIED ARTIFICIAL INTELLIGENCE FRAMEWORK

    公开(公告)号:US20240338570A1

    公开(公告)日:2024-10-10

    申请号:US18747561

    申请日:2024-06-19

    CPC classification number: G06N3/092

    Abstract: A deep reinforcement learning (DRL) intelligent decision-making platform based on a unified AI framework includes a parameter configuration module, a general-purpose module, an original environment module, an environment vectorization module, an environments maker, a mathematical utilities module, a model library and a runner. Parameters of a DRL model are selected through the parameter configuration module, and read by the general-purpose module. Based on the read parameters, a representer, a policy module, a learner, and an intelligent agent are called from the model library and created, where necessary function definitions and optimizers are called from the mathematical utilities module. Based on the read parameters, the environment vectorization module is created based on the original environment. The intelligent agent and environments are input into the runner to compute an action output, which executes the action output to realize the intelligent decision making.

    High-sensitivity flexible three-dimensional force tactile sensor and preparation method thereof

    公开(公告)号:US12044584B2

    公开(公告)日:2024-07-23

    申请号:US17771818

    申请日:2021-12-31

    CPC classification number: G01L1/144

    Abstract: A high sensitivity flexible three-dimensional force tactile sensor includes a hemispherical contact, wherein the hemispherical contact includes a tray with a groove on the surface and a hemispherical protrusion arranged in the groove. A flexible inverted cone component connected to the lower surface of the hemispherical contact, wherein a plurality of flexible triangular excitation electrode is arranged on the side surface of the flexible inverted cone component. A flexible common electrode surrounding part of the flexible triangular excitation electrode, wherein a first cavity with an opening is opened inside the flexible common electrode, parts of the flexible triangular excitation electrode and the flexible inverted cone component are arranged in the first cavity of the flexible common electrode. The flexible triangular excitation electrode and the flexible inverted cone component have no contact with the inner wall of the first cavity of the flexible common electrode to form an air cavity.

    CARBON FIBER AND GRAPHENE COMPOUNDED HIGH-STRENGTH POROUS MATERIAL, AND GAS DIFFUSION LAYER AND PREPARATION METHOD THEREFOR

    公开(公告)号:US20240170683A1

    公开(公告)日:2024-05-23

    申请号:US18282791

    申请日:2022-07-20

    Inventor: Junzhong WANG

    CPC classification number: H01M4/8807 H01M4/8605 H01M4/8846 H01M4/886 H01M4/96

    Abstract: A carbon fiber and graphene compounded high-strength porous material, and a gas diffusion layer and a preparation method therefor are provided. The carbon material integrates respective structures and characteristic advantages of a carbon fiber and graphene, complements each other, and has characteristics such as high mechanical strength (the carbon fiber is not cut off), hierarchical pore gradient distribution, good air permeability, good electric conductivity, good thermal conductivity, light weight, and high stability. The preparation method includes process steps such as graphene preparation, filament split of a carbon fiber bundle by spreading a liquid film, adsorption and anchoring of a filament by means of graphene, graphene coating, and high-temperature treatment. In the preparation process of the carbon-based gas diffusion layer, the carbon fiber is not cut off, the strength of the carbon fiber is kept, and the carbon-based gas diffusion layer is suitable for roll-to-roll batch preparation.

    ULTRA-WIDEBAND ELECTROMAGNETIC BAND GAP (EBG) STRUCTURE AND CIRCUIT BOARD

    公开(公告)号:US20240120633A1

    公开(公告)日:2024-04-11

    申请号:US18539132

    申请日:2023-12-13

    CPC classification number: H01P7/00 H05K1/0236

    Abstract: An ultra-wideband electromagnetic band gap (EBG) structure includes multiple EBG units in an array. Each EBG unit includes a power plane, a dielectric substrate and a ground plane from top to bottom. The power plane includes a patch, a coupled complementary split ring resonator (C-CSRR) and a plurality of semi-improved Z-bridge structures. Each edge of the patch is provided with a semi-improved Z-bridge structure. The C-CSRR is provided within a ring formed by the semi-improved Z-bridge structures. The Z-bridge structure includes a first horizontal branch, a first vertical branch, a second horizontal branch and a second vertical branch connected in sequence. The second vertical branch is connected to the patch. First horizontal branches of adjacent EBG units are connected to each other. A circuit board including the aforementioned EBG structure is also provided.

    System and method for detecting concentration of free SiO2 in coal dust

    公开(公告)号:US11940376B2

    公开(公告)日:2024-03-26

    申请号:US18147236

    申请日:2022-12-28

    Abstract: A system for detecting a concentration of free SiO2 in coal dust includes a first sampling tube and a second sampling tube for sampling the coal dust, a three-way control valve communicated with the first sampling tube and the second sampling tube respectively, a photoacoustic spectrometry detection device communicated with the three-way control valve through a connecting pipeline, and a SiO2 reaction tube for reacting SiO2 in the coal dust; and the SiO2 reaction tube is disposed on the second sampling tube. In the present disclosure, a coal dust sampling line is convenient to change by disposing the three-way control valve, and the first sampling tube and the second sampling tube are respectively communicated with the photoacoustic spectrometry detection device, so as to perform a differential accurate detection of the reacted CO content, and to obtain the SiO2 content.

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