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公开(公告)号：US20240252441A1
公开(公告)日：2024-08-01
申请号：US18425556
申请日：2024-01-29
Applicant: CRITITECH, INC.
Inventor： Gere S. DIZEREGA , Michael BALTEZOR , Sam CAMPBELL , Charles J. DECEDUE , Matthew MCCLOREY , Holly MAULHARDT
IPC: A61K9/16 , A61K9/00 , A61K31/337 , A61K39/00 , C07K16/28
CPC classification number: A61K9/1652 , A61K31/337 , C07K16/2818 , A61K9/0014 , A61K9/0019 , A61K9/0053 , A61K2039/54
Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, and intracystic injection.
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公开(公告)号：US20230364021A1
公开(公告)日：2023-11-16
申请号：US18354293
申请日：2023-07-18
Applicant: CRITITECH, INC.
Inventor： Jacob SITTENAUER , Joseph FARTHING , Mark WILLIAMS , Michael BALTEZOR , Gere DIZEREGA , Aranza Barreda ABARCA , Shelby CLARK
Abstract: Particles of at least 95% by weight of sorafenib, or a pharmaceutically acceptable salt thereof are provided, wherein the particles have a specific surface area (SSA) of at least 2 m2/g and have a mean particle size by volume distribution of between about 0.7 μm and about 8 μm, as are methods for their use, and methods for making such particles.
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公开(公告)号：US11583499B2
公开(公告)日：2023-02-21
申请号：US17333629
申请日：2021-05-28
Applicant: CRITITECH, INC.
Inventor： Gere S. Dizerega , Michael Baltezor , Sam Campbell , Charles J. Decedue , Matthew McClorey
IPC: A61K9/16 , A61K31/337 , C07K16/28 , A61K9/00 , A61K39/00
Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, and intracystic injection.
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公开(公告)号：US11523983B2
公开(公告)日：2022-12-13
申请号：US17315804
申请日：2021-05-10
Applicant: CRITITECH, INC.
Inventor： Gere S. diZerega , Michael Baltezor , Charles J. Decedue , Sam Campbell , Matthew McClorey , Marc Iacobucci , Holly Maulhardt
IPC: A61K9/10 , A61K9/00 , A61P35/00 , A61B8/08 , A61B8/12 , A61K9/107 , A61K9/14 , A61K31/337 , A61K47/26 , A61P1/18 , A61K9/16
Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
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公开(公告)号：US11458133B2
公开(公告)日：2022-10-04
申请号：US16839737
申请日：2020-04-03
Applicant: CRITITECH, INC.
Inventor： Mike Baltezor , Gere diZerega , Charles Decedue , Sam Campbell , Matt McClorey
IPC: A61P35/00 , A61K31/475 , A61K33/243 , A61K9/19 , A61K9/08 , A61K9/10 , A61K9/14 , A61K31/337 , A61K31/4439 , A61K31/4745 , A61K31/513 , A61K31/555 , A61K31/704 , A61K31/7048 , A61K31/7068 , A61K47/26 , A61K9/00 , A61K47/10
Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
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Patent Agency Ranking
公开(公告)号：US11104663B2
公开(公告)日：2021-08-31
申请号：US16650670
申请日：2018-09-28
Applicant: CRITITECH, INC.
Inventor： Mark Williams , Jacob Sittenauer , Shelby Clark , Joseph Farthing , Michael Baltezor , Matthew McClorey
IPC: C07D401/10 , A61K9/14 , A61K9/00 , A61P31/04
Abstract: The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.
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公开(公告)号：US20210259959A1
公开(公告)日：2021-08-26
申请号：US17315804
申请日：2021-05-10
Applicant: CRITITECH, INC.
Inventor： Gere S. diZerega , Michael Baltezor , Charles J. Decedue , Sam Campbell , Matthew McClorey , Marc Iacobucci , Holly Maulhardt
IPC: A61K9/00 , A61P35/00 , A61B8/08 , A61B8/12 , A61K9/107 , A61K9/14 , A61K31/337 , A61K47/26 , A61P1/18 , A61K9/10
Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
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公开(公告)号：US11033542B2
公开(公告)日：2021-06-15
申请号：US16512044
申请日：2019-07-15
Applicant: CRITITECH, INC.
Inventor： Mike Baltezor , Gere diZerega , Charles Decedue , Sam Campbell , Matt McClorey
IPC: A61K31/506 , A61K31/475 , A61K9/08 , A61K9/10 , A61K9/14 , A61K31/337 , A61K31/4439 , A61K31/4745 , A61K31/513 , A61K31/555 , A61K31/704 , A61K31/7048 , A61K31/7068 , A61K33/243 , A61K47/26 , A61P35/00 , A61K9/00 , A61K47/10
Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
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公开(公告)号：US10507195B2
公开(公告)日：2019-12-17
申请号：US15895197
申请日：2018-02-13
Applicant: CRITITECH, INC.
Inventor： Michael Baltezor , Joseph Farthing , Jake Sittenauer , Jahna Espinosa , Samuel Campbell , Matthew McClorey , Julia K. Fischer , Mark D. Williams , Gary Clapp
IPC: A61K31/337 , A61K9/00 , A61K9/10 , A61K9/14 , A61K9/16 , A61K9/51 , A61J3/02 , B01J19/10 , B01J19/26 , B01J2/04 , B01J3/00 , B01J4/00 , B01D46/24 , B01J3/02 , B05B1/34 , B05B13/02
Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
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公开(公告)号：US09814685B2
公开(公告)日：2017-11-14
申请号：US15174505
申请日：2016-06-06
Applicant: CRITITECH, INC.
Inventor： Michael Baltezor , Joseph Farthing , Jake Sittenauer , Jahna Espinosa , Samuel Campbell , Matthew McClorey , Julia K. Fischer , Mark D. Williams , Gary E. Clapp
IPC: A61K9/51 , A61K9/16 , A61K31/337 , B01J2/04 , B01J19/26 , B01J19/10 , B01J4/00 , A61K9/14 , A61K9/10 , A61K9/00 , B01J3/00
CPC classification number: A61K31/337 , A61J3/02 , A61K9/0019 , A61K9/10 , A61K9/14 , A61K9/1605 , A61K9/1682 , A61K9/1688 , A61K9/5192 , B01D46/24 , B01D2271/02 , B01J2/04 , B01J3/008 , B01J3/02 , B01J4/002 , B01J19/10 , B01J19/26 , B05B1/3489 , B05B13/0278 , B05D2401/90
Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
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