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公开(公告)号：US10427158B2
公开(公告)日：2019-10-01
申请号：US15260565
申请日：2016-09-09
Applicant: UNIVERSITÉ LAVAL , GENEPOC INC.
Inventor： Régis Peytavi , Sébastien Chapdelaine
IPC: G01N21/64 , G01N21/07 , G01N21/03 , B01F3/08 , B01F15/02 , B01F13/00 , B01L7/00 , B01L3/00 , G01N35/00 , C12Q1/686 , B01L9/00 , G01N35/04
Abstract: A fluidic centripetal apparatus for testing components of a biological material in a fluid is presented. The fluidic centripetal device is adapted to be received within a rotatable holder. The apparatus comprises a fluidic component layer having fluidic features on at least a front face and a bottom component layer bonded to a rear of the fluidic component layer thereby creating a fluidic network through which the fluid flows under centripetal force. In one embodiment, the fluidic feature may be a bottom-fillable chamber coupled to an entry channel for receiving the fluid, the chamber inlet being provided at an outer side of the bottom-fillable chamber. In another embodiment, the fluidic feature may be a retention chamber coupled to an entry channel for receiving the fluid, a container wholly provided in the retention chamber and containing a liquid diluent, the container maintaining the liquid diluent in the container until it releases it in the retention chamber upon application of an external force to the container, thereby restoring the fluidic connection between the liquid diluent and the fluid in the retention chamber. Additionally, the retention chamber can have a flow decoupling receptacle for receiving the fluid, located at the outer side of the retention chamber and interrupting a fluidic connection between the entry and exit of the retention chamber. A test apparatus and a testing method using a fluidic centripetal device for testing components of a biological material in a fluid are also provided.
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Patent Agency Ranking
公开(公告)号：US20150308958A1
公开(公告)日：2015-10-29
申请号：US14649660
申请日：2013-12-05
Applicant: GENEPOC INC. , UNIVERSITÉ LAVAL
Inventor： Hugo LEMIEUX , Sébastien CHAPDELAINE , David BÉLIVEAU-VIEL , Jean-François GRAVEL
IPC: G01N21/64
CPC classification number: G01N21/6486 , G01J3/021 , G01J3/0213 , G01J3/0216 , G01J3/0218 , G01J3/443 , G01J2003/102 , G01N21/6408 , G01N21/6445 , G01N21/645 , G01N21/763 , G01N2021/6419 , G01N2021/6471 , G01N2021/6484 , G01N2201/061
Abstract: An interrogation device for detecting luminescent light produced by analytes in a sample excited by multiple excitation light beams each having individual spectral contents, comprising a plurality of light sources each generating an excitation light beam; at least one detector for detecting the luminescent light produced by the sample; and an optical assembly defining distinct and fixed excitation light paths for each of the excitation light beams from the light sources to a common excitation site on the sample and defining a shared luminescence light path for the luminescent light from the excitation site on sample to the at least one detector, the excitation light paths and the luminescence light path being on a same side of the sample, the optical assembly including sample-side optics projecting the excitation light towards the sample and collecting luminescent light from the sample.
Abstract translation: 一种用于检测由各自具有各个光谱含量的多个激发光束激发的样品中的被分析物产生的发光光的询问装置，包括多个光源，每个光源产生激发光束; 用于检测由样品产生的发光的至少一个检测器; 以及光学组件，其为从光源到样品上的共同激发位置的每个激发光束定义不同且固定的激发光路径，并且限定用于从样品上的激发位点到该位置的发光的共享发光光路 至少一个检测器，激发光路径和发光光路位于样品的同一侧，光学组件包括样品侧光学器件，将激发光投射到样品并收集来自样品的发光。
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公开(公告)号：US10101274B2
公开(公告)日：2018-10-16
申请号：US14649660
申请日：2013-12-05
Applicant: GenePOC inc. , UNIVERSITÉ LAVAL
Inventor： Hugo Lemieux , Sébastien Chapdelaine , David Béliveau-Viel , Jean-François Gravel
Abstract: An interrogation device for detecting luminescent light produced by analytes in a sample excited by multiple excitation light beams each having individual spectral contents, comprising a plurality of light sources each generating an excitation light beam; at least one detector for detecting the luminescent light produced by the sample; and an optical assembly defining distinct and fixed excitation light paths for each of the excitation light beams from the light sources to a common excitation site on the sample and defining a shared luminescence light path for the luminescent light from the excitation site on sample to the at least one detector, the excitation light paths and the luminescence light path being on a same side of the sample, the optical assembly including sample-side optics projecting the excitation light towards the sample and collecting luminescent light from the sample.
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公开(公告)号：US20170056878A1
公开(公告)日：2017-03-02
申请号：US15260565
申请日：2016-09-09
Applicant: UNIVERSITÉ LAVAL , GENEPOC INC.
Inventor： Régis Peytavi , Sébastien Chapdelaine
CPC classification number: B01L3/50273 , B01F3/0861 , B01F13/0059 , B01F15/0212 , B01F15/0233 , B01F2215/0037 , B01L3/502715 , B01L3/502746 , B01L7/525 , B01L9/527 , B01L2200/027 , B01L2200/028 , B01L2200/0605 , B01L2200/0631 , B01L2200/0668 , B01L2200/0684 , B01L2200/147 , B01L2200/16 , B01L2300/023 , B01L2300/043 , B01L2300/0609 , B01L2300/0681 , B01L2300/069 , B01L2300/0803 , B01L2300/0867 , B01L2300/087 , B01L2300/18 , B01L2400/0409 , B01L2400/043 , B01L2400/0677 , B01L2400/0683 , B01L2400/082 , C12Q1/686 , G01N21/0332 , G01N21/07 , G01N21/645 , G01N35/00029 , G01N35/00871 , G01N2021/0325 , G01N2035/00158 , G01N2035/00495 , G01N2035/0091 , G01N2035/0451
Abstract: A fluidic centripetal apparatus for testing components of a biological material in a fluid is presented. The fluidic centripetal device is adapted to be received within a rotatable holder. The apparatus comprises a fluidic component layer having fluidic features on at least a front face and a bottom component layer bonded to a rear of the fluidic component layer thereby creating a fluidic network through which the fluid flows under centripetal force. In one embodiment, the fluidic feature may be a bottom-fillable chamber coupled to an entry channel for receiving the fluid, the chamber inlet being provided at an outer side of the bottom-fillable chamber. In another embodiment, the fluidic feature may be a retention chamber coupled to an entry channel for receiving the fluid, a container wholly provided in the retention chamber and containing a liquid diluent, the container maintaining the liquid diluent in the container until it releases it in the retention chamber upon application of an external force to the container, thereby restoring the fluidic connection between the liquid diluent and the fluid in the retention chamber. Additionally, the retention chamber can have a flow decoupling receptacle for receiving the fluid, located at the outer side of the retention chamber and interrupting a fluidic connection between the entry and exit of the retention chamber. A test apparatus and a testing method using a fluidic centripetal device for testing components of a biological material in a fluid are also provided.
Abstract translation: 提出了一种用于测试流体中生物材料的组分的流体向心装置。 流体向心装置适于容纳在可旋转的保持器内。 该装置包括在至少前表面上具有流体特征的流体组分层和结合到流体组分层的后部的底部组分层，从而形成流体网络，流体网络通过该流体网络在向心力的作用下流动。 在一个实施例中，流体特征可以是联接到入口通道的底部可填充室，用于接收流体，所述室入口设置在底部可填充室的外侧。 在另一个实施例中，流体特征可以是连接到用于接收流体的进入通道的保持室，完全设置在保持室中并容纳液体稀释剂的容器，容器将液体稀释剂保持在容器中，直到其释放 在对容器施加外力时，保留室，从而恢复液体稀释剂与保持室中的流体之间的流体连接。 此外，保持室可以具有流动分离插座，用于接收位于保持腔的外侧处的流体并且阻断保持室的入口和出口之间的流体连接。 还提供了一种使用流体向心装置测试流体中生物材料的组分的测试装置和测试方法。
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公开(公告)号：USD799715S1
公开(公告)日：2017-10-10
申请号：US29543358
申请日：2015-10-23
Applicant: GenePOC inc. , UNIVERSITE LAVAL
Designer： Sébastien Chapdelaine , Régis Peytavi , Thomas-Éric Beliveau , François Gaucher , Patrick Mainville
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