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公开(公告)号：US20250069878A1
公开(公告)日：2025-02-27
申请号：US18628049
申请日：2024-04-05
Applicant: MSTM, LLC
Inventor： Charles N. McEwen , Milan Pophristic
Abstract: The disclosed invention relates to mass spectrometry (MS) and related instruments (‘analyzer device’). More specifically, the disclosed description relates to an improved apparatus, herein termed a vacuum chamber assembly device configured to enable a multitude of functions to enhance ionization and analyte ion transfer through the application of a plurality of Ports. The Ports being designed to provide on a single analyzer device capabilities of atmospheric pressure ionization, inlet ionization, and vacuum ionization rapidly available in order to maximize information obtained from a sample in a timely manner. Ports may also have auxiliary functions which expand and improve the available ionization methods as well as provide functions not commonly available.
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公开(公告)号：US20250157805A1
公开(公告)日：2025-05-15
申请号：US19018656
申请日：2025-01-13
Applicant: MSTM, LLC
Inventor： Milan Pophristic
Abstract: An ionizing system includes a flange device for connection to a mass spectrometer or ion mobility spectrometer having the property of providing a barrier between the lower pressure region of the spectrometer and a higher pressure region substantially at atmospheric pressure, and a channel therethrough providing fluid communication between the higher and lower pressure regions. A plate device independent of the flange device which can accommodate multiple samples, such as a sample plate device, when placed over the channel in the flange device substantially seals the channel. Sliding the sample plate device while in intimate contact with the flange device provides a means to sequentially and rapidly expose said samples to the opening of the channel and thus the lower pressure region. Samples are ionized when exposed to the lower pressure region in as little as one sample per second using multiple ionization methods.
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