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    Protrudent analyte sensor
    4.
    发明授权
    Protrudent analyte sensor 有权
    突出分析物传感器

    公开(公告)号：US08032198B2

    公开(公告)日：2011-10-04

    申请号：US11348894

    申请日：2006-02-07

    Applicant: Nannette M. Van Antwerp ,  Udo Hoss

    Inventor： Nannette M. Van Antwerp ,  Udo Hoss

    IPC: A61B5/05 ,  A61B5/00

    CPC classification number: A61B5/153 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992

    Abstract: The methods and apparatus for detecting an analyte in blood are useful for detecting an analyte in tissue of a subject. The apparatus comprises a sensor, which comprises an elongated conductive material having a protrudent end, the protrudent end comprising an electrode that detects the presence of an analyte; a substrate affixed to the conductive material; and a support having an external surface, a proximal end, and a distal end. The conductive material is positioned on the support and the protrudent end of the conductive material protrudes beyond the distal end of the support. Optionally, the sensor is suspended within the lumen of a venous flow device. Typically, only a portion of the sensor is suspended within the lumen of the venous flow device, said portion comprising the protrudent end of the conductive material. Alternatively, the conductive material is positioned on the external surface of the intravenous infusion catheter.

    Abstract translation: 用于检测血液中分析物的方法和装置可用于检测受试者组织中的分析物。 该装置包括传感器，其包括具有突出端的细长导电材料，该突出端包括检测分析物的存在的电极; 固定在导电材料上的基板; 以及具有外表面，近端和远端的支撑件。 导电材料定位在支撑件上，并且导电材料的突出端突出超出支撑件的远端。 可选地，传感器悬挂在静脉流动装置的内腔内。 通常，只有一部分传感器悬挂在静脉流装置的内腔内，所述部分包括导电材料的突出端。 或者，导电材料定位在静脉输液导管的外表面上。

    INJECTION PORT DEVICE ADAPTED FOR USE WITH INSULIN PUMP
    5.
    发明申请
    INJECTION PORT DEVICE ADAPTED FOR USE WITH INSULIN PUMP 审中-公开
    注射口装置适用于胰岛素泵

    公开(公告)号：US20110160696A1

    公开(公告)日：2011-06-30

    申请号：US12982781

    申请日：2010-12-30

    Applicant: Udo Hoss

    Inventor： Udo Hoss

    IPC: A61M5/00

    CPC classification number: A61M39/02 ,  A61M5/14248 ,  A61M5/158 ,  A61M2039/0205

    Abstract: An injection port comprises a body having an outlet delivery cannula configured to pierce subcutaneous tissue of a patient to deliver medication. The port includes multiple injection sites, each of which can be used multiple times, and each of which is sealed. Each injection port is configured to temporarily receive a delivery device and reseal itself when the delivery device is removed. In one embodiment, a seal includes a pierceable stationary septum that reseals itself when a sharp cannula is removed. One injection site also includes locking features to receive a locking device of a delivery device and temporarily lock the delivery device in place at the injection site. The locking device may later be unlocked when delivery is complete and removed. In one application, a diabetic may use one injection site for syringes during the day and the locking injection site for a insulin pump during sleeping hours.

    Abstract translation: 注射口包括具有出口输送套管的主体，其配置成刺穿患者的皮下组织以递送药物。 该港口包括多个注射部位，每个注射部位可以多次使用，每个注射部位都密封。 每个注射口被配置为临时接收输送装置，并且在递送装置被移除时重新密封自身。 在一个实施例中，密封件包括可刺穿的静止隔膜，当清除尖锐的插管时，其可自行吸收。 一个注射部位还包括用于接收输送装置的锁定装置的锁定特征，并将输送装置临时锁定在注射部位的适当位置。 此后，锁定装置可以在传送完成并被移除时被解锁。 在一个应用中，糖尿病患者可以在白天使用一个注射部位用于注射器，并且在睡眠时间期间可以使用胰岛素泵的锁定注射部位。

    Analyte Sensors Comprising Self-Polymerizing Hydrogels
    6.
    发明申请
    Analyte Sensors Comprising Self-Polymerizing Hydrogels 审中-公开
    包含自聚合水凝胶的分析物传感器

    公开(公告)号：US20110124993A1

    公开(公告)日：2011-05-26

    申请号：US12624767

    申请日：2009-11-24

    Applicant: Balasubrahmanya S. Bommakanti ,  Gary Sandhu ,  Udo Hoss

    Inventor： Balasubrahmanya S. Bommakanti ,  Gary Sandhu ,  Udo Hoss

    IPC: A61B5/1468 ,  G01N27/26

    CPC classification number: A61B5/1473 ,  C12Q1/006

    Abstract: Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a self-polymerizing hydrogel, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

    Abstract translation: 通常，本公开的实施方案涉及通过包含自聚合水凝胶而具有改进的感测层分布均匀性的分析物确定方法和装置（例如，电化学分析物监测系统），其中感测层设置在接近于 体内和/或体外分析物传感器的工作电极，例如使用分析物传感器和/或测试条的连续和/或自动体内监测。 还提供了在分析物监测中使用例如电化学分析物传感器的系统和方法。

    Dynamic Analyte Sensor Calibration Based On Sensor Stability Profile
    9.
    发明申请
    Dynamic Analyte Sensor Calibration Based On Sensor Stability Profile 审中-公开
    基于传感器稳定性分析的动态分析仪传感器校准

    公开(公告)号：US20100274515A1

    公开(公告)日：2010-10-28

    申请号：US12769639

    申请日：2010-04-28

    Applicant: Udo Hoss ,  John Charles Mazza

    Inventor： Udo Hoss ,  John Charles Mazza

    IPC: G06F19/00

    CPC classification number: A61B5/1495 ,  A61B5/14532 ,  G16H40/40

    Abstract: Dynamic sensor calibration schedule management including determining a stability profile of an in vivo analyte sensor in fluid contact with a biological fluid, processing the determined stability profile in conjunction with calibration criteria for the analyte sensor, and modifying a predetermined sensor calibration schedule based on the processed stability profile is provided.

    Abstract translation: 动态传感器校准计划管理，包括确定与生物流体流体接触的体内分析物传感器的稳定性分布，结合分析物传感器的校准标准处理所确定的稳定性曲线，以及基于所处理的 提供稳定性曲线。

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