公开(公告)号：US20220008017A1

公开(公告)日：2022-01-13

申请号：US17370860

申请日：2021-07-08

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Junli Ou ,  Hyun Cho ,  Ting Chen ,  Erwin S. Budiman ,  Stephen Oja ,  Kuan-Chou Chen

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/1468

Abstract: A method of operating an analyte device includes: receiving an analyte signal measured from an analyte sensor device having a sensor tail; generating adjusted analyte data based on the analyte signal, the generating the adjusted analyte data including reducing a background signal in the analyte signal in accordance with an offset signal; computing an analyte value based on the adjusted analyte data; and displaying the analyte value on a display device.

公开(公告)号：US12290359B2

公开(公告)日：2025-05-06

申请号：US17138477

申请日：2020-12-30

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Yi Wang ,  Hyun Cho ,  Benjamin J. Feldman ,  Kuan-Chou Chen ,  Lam N. Tran ,  Stephen Oja ,  Tianmei Ouyang

IPC: A61B5/1486 ,  A61B5/145

Abstract: Multiple analytes may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using analyte sensors capable of detecting multiple analytes. Certain analyte sensors capable of the detection of multiple analytes may include first and second working electrodes, analyte-responsive active areas disposed on each of the working electrodes, and reference and counter electrodes. Analyte sensors that include multiple working electrodes but do not include reference and counter electrodes can also be used in conjunction with another sensor that contains reference and counter electrodes, such that these electrodes are shared.

公开(公告)号：US12076145B2

公开(公告)日：2024-09-03

申请号：US16259157

申请日：2019-01-28

Applicant: Abbott Diabetes Care Inc.

Inventor： Kuan-Chou Chen ,  Tianmei Ouyang ,  Stephen Oja ,  Benjamin Feldman ,  Hyun Cho ,  Lam Tran ,  Mark Eshoo

IPC: A61B5/1486 ,  A61B5/145 ,  G01N27/327

CPC classification number: A61B5/1486 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/14503 ,  G01N27/3271

Abstract: A lactate-responsive enzyme may form the basis for lactate detection and quantification using an electrochemical analyte sensor. Various features may be incorporated within an analyte sensor containing a lactate-responsive enzyme, particularly lactate oxidase, to improve sensitivity and response stability of the analyte sensor. Such analyte sensors may comprise: a working electrode having an active area disposed thereon, and a mass transport limiting membrane overcoating at least the active area upon the working electrode. The active area comprises at least a polymer, an albumin, and a lactate-responsive enzyme that is covalently bonded to the polymer. The mass transport limiting membrane may comprise at least a crosslinked polyvinylpyridine homopolymer or copolymer. The analyte sensors may determine a lactate concentration in a biological fluid, particularly in vivo, which may be correlated to various physiological conditions.

公开(公告)号：US20210219885A1

公开(公告)日：2021-07-22

申请号：US17138477

申请日：2020-12-30

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Yi Wang ,  Hyun Cho ,  Benjamin J. Feldman ,  Kuan-Chou Chen ,  Lam N. Tran ,  Stephen Oja ,  Jonathan D. McCanless

IPC: A61B5/1486 ,  A61B5/145

Abstract: Multiple analytes may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using analyte sensors capable of detecting multiple analytes. Certain analyte sensors capable of the detection of multiple analytes may include first and second working electrodes, analyte-responsive active areas disposed on each of the working electrodes, and reference and counter electrodes. Analyte sensors that include multiple working electrodes but do not include reference and counter electrodes can also be used in conjunction with another sensor that contains reference and counter electrodes, such that these electrodes are shared.

公开(公告)号：US20190320947A1

公开(公告)日：2019-10-24

申请号：US16259157

申请日：2019-01-28

Applicant: Abbott Diabetes Care Inc.

Inventor： Kuan-Chou Chen ,  Tianmei Ouyang ,  Stephen Oja ,  Benjamin Feldman ,  Hyun Cho ,  Lam Tran ,  Mark Eshoo

IPC: A61B5/1486 ,  A61B5/145

Abstract: A lactate-responsive enzyme may form the basis for lactate detection and quantification using an electrochemical analyte sensor. Various features may be incorporated within an analyte sensor containing a lactate-responsive enzyme, particularly lactate oxidase, to improve sensitivity and response stability of the analyte sensor. Such analyte sensors may comprise: a working electrode having an active area disposed thereon, and a mass transport limiting membrane overcoating at least the active area upon the working electrode. The active area comprises at least a polymer, an albumin, and a lactate-responsive enzyme that is covalently bonded to the polymer. The mass transport limiting membrane may comprise at least a crosslinked polyvinylpyridine homopolymer or copolymer. The analyte sensors may determine a lactate concentration in a biological fluid, particularly in vivo, which may be correlated to various physiological conditions.

公开(公告)号：US20230225615A1

公开(公告)日：2023-07-20

申请号：US17928794

申请日：2021-06-07

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Erwin S. Budiman ,  Yi Wang ,  Benjamin Jay Feldman ,  Hyun Cho ,  Kuan-Chou Chen ,  Lam N. Tran ,  Stephen Oja ,  Tianmei Ouyang

IPC: A61B5/00 ,  A61B5/145

CPC classification number: A61B5/0022 ,  A61B5/145 ,  A61B5/6833

Abstract: Various embodiments of systems, devices and methods for improving the accuracy of an analyte sensor and for detecting sensor fault conditions are disclosed. According to some embodiments, these systems, devices, and methods can utilize a first data collected by a glucose sensor and a second data collected by a secondary sensing element. In some embodiments, the secondary sensing element can be one of a lactate sensing element, a ketone sensing element, or a heart rate monitor, among others.