公开(公告)号：US3869274A

公开(公告)日：1975-03-04

申请号：US28288972

申请日：1972-08-21

Applicant: ABBOTT LAB

Inventor： CROVETTI ALDO JOSEPH ,  KENNEY DONALD SYKES ,  LYNCH DON MURL ,  STEIN ROBERT GEORGE

IPC: A01N47/38 ,  A01N43/56 ,  A01N47/16 ,  C07D231/16 ,  A01N5/00

CPC classification number: C07D231/16

Abstract: WHERE R, R2, R3 and R5 are selected from the group consisting of C2-C20 alkyl, hydrogen, halo, cycloalkyl, aryl, substituted aryl, and haloalkyl; and R1 and R4 are selected from the group consisting of hydrogen lower-alkyl, aryl, haloalkyl, halothioalkyl, arylthio, alkylthio, substituted arylthio, hydroxyalkyl, hydroxyhaloalkyl, alkylcarbamoyl, dialkylcarbamoyl, aryl substituted carbamoyl, substituted diarylcarbamoyl, alkylarylcarbamoyl, alkylsulfonyl, haloalkylsulfonyl, arylsulfonyl, substituted arylsulfonyl, formyl, carboalkoxy, carboalkoxy, pyranyl, thiocarbamoyl, halocarboalkoxy, aroyl, substituted aroyl, aryloxyaceto, substituted aryloxyaceto, arylthioaceto, substituted arylthioaceto, benzyl substituted benzyl, phenacetyl, substituted phenacetyl, phosphonoalkyl, thiophosphonoalkyl, and acetylanilide with the proviso that when R5 is chloro and R3 is hydrogen, the nitrogen in the one position is substituted.

WHERE R, R2, R3 and R5 are selected from the group consisting of alkyl, hydrogen, halo, cycloalkyl, aryl, substituted aryl and haloalkyl; and R1 and R4 are selected from the group consisting of hydrogen, loweralkyl, aryl, substituted aryl, haloalkyl, halothioalkyl, arylthio, alkylthio, substituted arylthio, hydroxyalkyl, hydroxyhaloalkyl, alkylcarbamoyl, dialkylcarbamoyl, aryl substituted carbamoyl, substituted diarylcarbamoyl, alkylarylcarbamoyl, alkylsulfonyl, haloalkylsulfonyl, arylsulfonyl, substituted arylsulfonyl, formyl, carboalkoxy, carboaryloxy, pyranyl, thiocarbamoyl, halocarboalkoxy, aroyl, substituted aroyl, aryloxyaceto, substituted aryloxyaceto, arylthioaceto, substituted arylthioaceto, benzyl, substituted benzyl, phenacetyl, substituted phenacetyl, phosphonoalkyl, thiophosphonoalkyl, acetylanilide and metallic salts of any of the foregoing R1 and R4 groups, in an agronomically acceptable carrier. Also covers certain 4-nitropyrazoles having a formula selected from the group consisting of:

Covers a method of inducing abscission of fruit by applying a chemical composition containing an effective amount of a 4nitropyrazole as the active ingredient in an agronomically acceptable carrier. Said composition comprises in addition to said carrier an effective amount of a compound having a formula selected from the group consisting of:

公开(公告)号：US3681436A

公开(公告)日：1972-08-01

申请号：US3681436D

申请日：1970-08-20

Applicant: ABBOTT LAB

Inventor： LYNCH DON MURL ,  COLE JOHN WAYNE

IPC: C07C39/17 ,  C07C39/23 ,  C07C69/16 ,  C07C39/12 ,  C07C43/22

CPC classification number: C07C39/17 ,  C07C39/23 ,  C07C2602/08 ,  Y10S514/843

Abstract: The present invention is directed to 1-(4-substituted benzyl)indans and simple analogs thereof; they have been found to inhibit the metabolic function of reproductive organs when administered to female, warm-blooded animals in very small doses.

Abstract translation: 本发明涉及1-（4-取代苄基）茚满及其简单类似物; 当以非常小的剂量施用于雌性，温血动物时，已经发现它们抑制生殖器官的代谢功能。

公开(公告)号：US3442893A

公开(公告)日：1969-05-06

申请号：US3442893D

申请日：1966-05-23

Applicant: ABBOTT LAB

Inventor： LYNCH DON MURL

IPC: C07D213/30 ,  C07D31/34 ,  C07D29/16 ,  C07D31/28

CPC classification number: C07D213/30