公开(公告)号：US3842069A

公开(公告)日：1974-10-15

申请号：US37238773

申请日：1973-06-21

Applicant: ABBOTT LAB

Inventor： JONES P ,  MARTIN J ,  TADANIER J ,  MCALPINE J ,  PAUVLIK J

IPC: C07H17/08 ,  C07C129/18

CPC classification number: C07H17/08

Abstract: 1. A 4"-DEOXY-4"-OXOERYTHROMYCIN COMPOUND SELECTED FROM THE GROUP CONSISTING OF

2,10-DI(O=),4,5,7,9,11,13,-HEXA(H3C-),4-((4,6-DI(H3C-),

4-(H3C-O-),5-(O=),6-(H3C-)-TETRAHYDROPYR-2-YL)-O-),6-

((3-(R1-O-),4-((H3C)2-N-),6-(H3C-)-TETRAHYDROPYR-2-YL)-

O-),7-(HO-),12-(R-O-),14-(H5C2-)-OXACYCLOTETRADECANE

WHERE R IS -CHR2SR3 WHERE R'' IS HYDROGEN OR LOWERALKYL, R3 IS LOWERALKYL AND R1 IS HYDROGEN OR LOWERALKANOYL AND;

2-(O=),3,5,7,9,11,13-HEXA(H3C-),4-((4,6-DI(H3C-),

4-(H3C-O-),5-(O=),6-(H3C-)-TETRAHYDROPYR-2-YL)-O-),6-

((3-(R1-O-),4-((H3C)2-N-),6-(H3C-)-TETRAHYDROPYR-2-YL)-

O-),7,10-(-O-),10,12-(-O-CH(-R2)-O-),12-(H5C2-)-

OXACYCLOTETRADECANE

WHERE R1 AND R2 ARE AS BEFORE DEFINED.